BMED 1110 Midterm Review
The nervous system includes?
the brain, spinal cord, and a network of nerves
sends messages back and forth between the brain and body
Astrocytes-
maintain blood-brain barrier
control levels of neurotransmitters around synapes
regulate ions
provides metabolic support\
Ependymal cells-
line spinal cord and ventricles of the brain
involved in producing cerebrospinal fluid (CSF)
Oligodendrocytes-
myelinate CNS axons
provide structural framework
Microglia
brains immune cells (similar to macrophages)
remove dead cells and pathogens through phagocytosis
Satellite cells
surround neuron cell bodies in ganglia
regulate neurotransmitter levels
Schwann cells
myelinate neurons in PNS
maintain and regenerate neurons after injury
Neurophysiology
study of the functional properties of neurons, glia, and networks
What is an ion channel, and what kind of channels are there?
allows molecules to cross the membrane
voltage-gated channel
chemically activated channel
mechanically gated channel
What ions are involved in resting membrane and action potential?
Na+ and K+
What occurs in an action potential?
Depolarizing voltage activates the Na+ ion channels in neuronal membrane. The channels open in a positive feedback loop which results in a greater amount of Na+ in the cell than K+. The membrane depolarizes to equilibrium(55mV). Action potential is generated.
What occurs at when an action potential returns to resting membrane potential?
Na+ channels become less active as the action potential decreases, K+ current leads to a period of hyperpolarization before deactivating and returning to the resting phase.
Excitatory post-synaptic potentials- (EPSPs)
binding of neurotransmitter leads to opening of ion channels
cation influx in post-synaptic process
depolarization of membrane
EPSP depolarization are recorded in post synaptic cell to a certain excitatory stimulus
Depolarization associated with EPSPs can trigger action potentials if summation were to occur
Inhibitory postsynaptic potentials-
ion channels allow postsynaptic anion influx when open
hyperpolarization of the membrane occurs due to an influx of Cl- and efflux of K+
important for modulating the neurons response to excitatory input at synapse
found in proximal dendrite and soma
influence the dendritic tree
Acetylcholine is
a neurotransmitter that widely spread through the nervous system, including neuromuscular junction and autonomic NS.
The higher brain is responsible for
cognitive and behavioral processes
The PNS-
connects the brain and spinal cord to the rest of the body
transmits information to and from the CNS
The CNS is responsible for-
Receiving, processing, and responding to signals
Function of the frontal lobe:
voluntary motor function
problem-solving
attention
memory
language
Function of the parietal lobe:
processing sensory information
contains somatosensory cortex
Function of occipital lobe
receives visual information
Function of the temporal lobe
auditory
speech comprehension
Basal nuclei are responsible for?
Movements and coordination
The thalamus controls?
sensory receptors that are located thought the body and process the information for distribution to the appropriate cortical area. Regulates consciousness and sleep.
The hypothalamus controls?
heart rate, blood pressure, appetite, thirst, temperature, and the release of hormones.
The function of the pons?
connects the medulla oblongata and the thalamus, relays impulses from motor cortex to cerebellum, medulla, and thalamus
The medulla oblongata controls?
autonomic functions (respiratory system, cardiovascular system, vasomotor center, vomiting, swallowing, coughing, and sneezing)
The cerebellum is responsible for?
coordinated voluntary movements. coordination in arms and legs, maintains balance and posture. communication from pons to cerebellum. voluntary muscle contractions.
The limbic system controls?
emotion, memory, and motivation.
The hypothalamus receives most of the limbic output.
Reticular formation is?
Reticular activation system (RAS), responsible for consciousness. filters out repetitive, weak stimuli, prevents brain from responding to unimportant info and sensory overload.
The spinal cord is responsible for
involuntary and voluntary reflexes
Examples of cognitive higher brain functions include-
Intellectual function, memory, speech, language, complex perception, orientation, attention, judgement, planning, decision making
Examples of behavioral higher brain functions include-
psychological make-up, traits, response styles
Osseous tissue is responsible for
hard and mineralized connective tissues
reservoir minerals (calcium and phosphorus)
fat storage (yellow marrow)
hematopoiesis (red marrow)
The axial skeleton consists of how many bones?
80
The axial skeleton includes?
spine, skull, ribcage
(protects internal structures, origin of muscles)
The appendicular skeleton has how many bones?
126
The appendicular skeleton includes-
arms, legs, pelvic girdle, and pectoral girdle.
(key role in movement. insertion of most muscles)
Function of the skeleton is
protection, movement, and support
The function of joints are
to hold bones together, allow bones to move, bones to articulate with at least one other bone (EXCEPT HYOID)
fibrous joints are
immovable
synovial joints are
freely movable
Function classification of joints are:
focus on amount of movement
synarthrosis
amphiarthrosis
diarthosis
Structural classification of joints
seperates the bony regions at the joint
fibrous
cartilage
joint cavity
Contractility is
ability of muscle cells to forcefully shorten
Excitability is -
ability to respond to a stimulus, which can be delivered from a motor neuron or hormone
Extensibility is-
the ability of a muscle to be stretched.
Elasticity is-
the ability to recoil or bounce back to the muscle's original length after being stretched
Functions of muscles
movement
maintenance of posture
respiration
heat generation
communication
constriction of organs and blood vessels
pumping blood
Skeletal muscles are
long, cylindrical fibers, striated, many peripherally located nuclei
The function of skeletal muscles is
voluntary movement, produces heat, protects organs.
Skeletal muscles are located-
attached to bones and around entry and exit sites in body (ex. mouth, anus)
Cardiac muscles are-
short, branched, striated, single central nucleus
The function of cardiac muscles-
contracts to pump blood
Cardiac muscle is located in
heart (duh)
Smooth muscles are
short, spindle shaped, no striations, single nucleus in each fiber
Function of smooth muscle is:
involuntary movement, involuntary control of respiration, digestion, move secretions, regulates flow of blood in arteries by contraction.
Smooth muscle is located in
walls of major organs and passageways