PATHO FINAL
Your patient's red blood cell count is slightly elevated today. This might be explained by what?
-Gender difference
-Situational variation
- Illness
All of data that you need to gather before making a diagnosis, what factors need to be considered?
The problem and its definition
The etiology of the problem
The defining characteristics or risk factors of the problem
Aldosterone may increase during stress, leading to..... Select all that apply
Decreased urinary output
Increased sodium retention
Increased blood pressure
Chronic activation of stress hormones can lead to..... (Select all that apply)
-Cardiovascular disease
-Depression
-Impaired cognitive function
-Autoimmune disease
Bacteria cause injury to cells by which mechanisms. (Select all that apply)
- Producing exotoxin
- Producing endotoxins
- Producing destructive enzymes
- Evoking an immune reaction
Viruses differ from most bacteria in that they act in which of the following ways? ( Select all that apply)
-Enter the host cell
-use the host's metabolic processes to survive and replicate
-and do not produce toxins
Breast cancer in women who have the breast cancer gene
occurs at an earlier age
Side effects of chemotherapy include.... (select all that apply)
-Anemia
-Nausea
-Bleeding
-Infections
-Bone marrow suppression
Which viruses are associated with human cancers? ( select all that apply)
-HPV
-EBV
-HBV
-HCV
-HIV
RhoGAM is given to an Rh-negative mother in order to prevent.... WHAT
RH incompatibility in a future pregnancy
The principle Ig mediator of type I hypersensitivity reactions is
IgE
Secondary immune deficiency problems may be caused by which of the following? (select all that apply)
Surgery
High blood sugar
Corticosteroids
Low protein level
What Diseases are due to type IV hypersensitivity? ( select all that apply)
Leprosy
Tuberculosis
Herpes simplex infection
Which form of leukemia demonstrate the presence of Philadelphia chromosome?
CML ( chronic myeloid leukemia)
Burkitt lymphoma is most closely associated with... WHAT ?
-Epstein
- Barr virus
CML symptom's
Fatigue
Weight loss
Bleeding
Abdominal discomfort
Sweats
Which clinical findings describe the typical presentation of ALL ? (select all that apply)
-Pain in long bone
-Infection
-Fever
-Bruising
A low mean corpuscular hemoglobin concentration (MCHC) and mean corpuscular volume (MCV) are characteristics of which type of anemia ?
Iron deficiency
The cause of the most common form of anemia is what ???
Iron deficiency anemia
Anemia related to vitamin B12 or folate deficiency is characterized by what laboratory features? All that apply
- RBC count of 500,000-750,000 cells/mm3
- WBC count of 4000-5000 cells/mm3
Regarding iron deficiency anemia, what laboratory features are typically decreased? (select all that apply)
-MCV
- MCH
- MCHC
The final step in clot formation is.... what?
Fibrinogen to fibrin
Activation of the extrinsic pathway of coagulation is initiated by... what?
Tissue thromboplastin
The megakaryocyte is a precursor to.... what?
Platelets
Disseminated intravascular coagulation may be treated with heparin therapy to do what ??
Inhibit clotting factor consumption
A deficiency of von Willebrand factor impairs.. what?
Platelet adhesion to injured tissue
What is involved in the release of plasminogen activators? ( select all that apply)
-Factor XII
-HMWK
- Kallikrein
- Thrombin
Diseases may be associated with a bleeding problem? (select all that apply)
-urinary retention
- renal failure
- cirrhosis
-systemic lupus erythematosus
- ovarian cancer
Which is not considered to be a risk factor for thrombus formation?
Thrombocytopenia
Which clinical finding is indicative of compartment syndrome?
Absent peripheral pulse
The pain characteristics of chronic venous insufficiency. ( select all that apply)
- Aching and cramping in the affected area
- relief with elevation to the area
- relief with ambulation
High blood pressure increases the workload of the left ventricle because it increases what??
Afterload
High blood pressure increases the risk of which conditions?
- Stroke
- renal disease
-ischemic disease
Atherosclerosis puts a patient at risk for which of the following problems? ( select all that apply)
-ischemic stroke
- retinal injury
- renal impairment
Orthostatic hypotension is a risk factor for which conditions? ( select all that apply)
- stroke
- cognitive impairment
- death
Primary treatment for myocardial infarction is directed at
decreasing myocardial oxygen demands
Patient's presenting with symptoms of unstable angina and no ST segment elevation are treated with:
Antiplatelet drugs
Aortic regurgitation is associated with
Diastolic murmur
Angina caused by coronary artery spasm is called ____ angina
Prinz metal variant
Atherosclerotic plaques with large lipid cores are prone to:
Rupture
Acute coronary syndrome in the presence of thrombosis may present with which manifestations? ( select all that apply)
-Unstable angina
-MI
-Sudden cardiac arrest
Diagnostic tests used to diagnose or confirm MI include which of the following? (select all that apply)
-Electrocardiogram
-Cardiac catheterization
-Echocardiography
-Radionuclide scintigraphy
First degree heart block is characterized by... what?
Prolonged PR interval
A patient is diagnosed with heart failure with preserved ejection fraction (HFpEF) This pt is most likely described as an .... what?
elderly woman without history of MI
The most common causes of heart failure include which of the following? ( select all that apply)
Coronary heart disease
Heart attack
A patient experiencing shock may exhibit which signs and symptoms? (select all that apply)
Pulse of more than 100 bpm
Fast and deep respirations
Anaphylactic shock signs and symptoms in a patient? (select all that apply )
Hypotension
Urticaria
Angioedema
Wheezing
Septic shock is commonly associated with Gram-negative infections and Gram positive organisms that enter the body through which body systems? (select all that apply)
Genitourinary tract
Gastrointestinal tract
Respiratory tract
Skin
Emphysema results from destruction of alveolar walls and capillaries because of ... what?
Release of proteolytic enzymes from immature cells
Chronic bronchitis often leads to cor pulmonale because of what???
Increased pulmonary vascular resistance
Cystic fibrosis is associated with what??
Bronchiectasis
Croup is characterized by... what ??
Barking cough
Hoarseness
Stridor
Difficulty breathing
COPD leads to a barrel chest, because it causes... ?
Air trapping
Characteristics of asthma? (select all that apply)
Edema
Airway inflammation
Collagen deposits
The hallmark manifestations of acute respiratory distress syndrome is .... what ?
Hypoxemia
Empyema is defined as an... what ?
Infection in the pleural space
A major cause of treatment failure in tuberculosis is... what?
Noncompliance to medication regimen
Bacteria pneumonia leads to hypoxemia caused by... what?
Cardiogenetic pulmonary edema
A common characteristic of viral pneumonia is... what?
Dry cough
Which alteration can lead to edema?
Decreased lymphatic flow
Hypernatremia may be caused by what?
Excessive sodium intake
Gain of sodium
Loss of water
Clinical manifestations of moderate to severe hypokalemia include.. what?
Muscle weakness and cardiac dysrhythmias
A patient has a positive Chvostek sign. The nurse interprets this as a sign of what??
Increase neuromuscular excitability
Acid that kidneys unable to excrete?
Carbonic
Vomiting of stomach contents or continuous nasogastric suctioning may predispose to development of ... what?
Metabolic acid deficit
Respiratory acidosis may be caused by... what ?
Hypoventilation
Diarrhea causes... what?
Metabolic acidosis
Uncompensated metabolic alkalosis would result in... what?
Increase PH
Increase HCO3
A patient is diagnosed with starvation ketoacidosis. What s/s should you anticipate in your assessment?
Rapid and deep breathing
Abdominal pain
Lethargy
The pathophysiologic basis of acute glomerulonephritis is... what?
Immune complex reaction
Nephrotic syndrome involves loss of large amounts of _____ in the urine
Protein
One cause of an extrinsic renal system obstruction is ... what
pelvic tumor
Hyperlipidemia occurs in nephrotic syndrome because ??
hepatocytes synthesize excessive lipid
Risk factors for renal carcinoma? (all that apply)
Genetic
cigarette smoking
obesity
chemical
Manifestations of acute pyelonephritis? ( all that apply)
Dehydration
Low urine output symptoms
fever
chills
costovertebral angle tenderness
urosepesis
The oliguric phase of acute tubular necrosis is characterized by... what?
Fluid excess and electrolyte imbalance
Osteoporosis commonly occurs in patients with end stage renal disease because of ???
Hyperparathyroidism
A pt with renal disease is at risk for developing uremia as the nephrons progressively deteriorate because?
GFR declines
The most helpful laboratory value in the monitoring the progression of declining renal function is... what ?
serum creatinine
The most common causes of acute tubular necrosis (ATN) is ??
Ischemic conditions
Postrenal acute kidney injury may be caused by what
Bilateral kidney stones
Anemia in people how have end stage chronic renal disease is caused by what ?
decreased secretion of erythropoietin
Signs of chronic renal failure? (select all that apply)
High serum potassium levels
high serum phosphorous
high blood urea nitrogen
high anemia
The diet for a pt with chronic kidney disease should include which of the following ( select all that apply)
high carbohydrates
low sodium
low potassium
low phosphorous
high calories
A patient missed two dialysis sessions. What conditions will the pt likely demonstrate?
Lethargy
increased BUN
skeletal muscle weakness
hyperkalemia
rapid breathing
Group with highest risk for UTI
sexually active females
A ureterocele is what ?
cystic dilation of the distal ureter near insertion into the bladder
The greatest risk factor for bladder cancer is what??
smoking
males
older than 55 years old
Caucasian
Vesicoureteral reflux is associated with... what?
Recurrent cystitis
Which situations increase the risk of urge incontinence
diabetes
hysterectomy
antidepressants
diuretics
bp meds
Characteristics of cystitis ?
women
catheterization of the bladder
fostered by stasis of urine
Cystitis symptoms? All that apply
dysuria
urinary frequency
cloudy, bloody smelling urine
low back pain
fever
Cryptorchidism is ... what?
undescended testicles
A progressive decrease in the force of the urinary stream, dribbling or urine and difficulty initiating the urinary stream are characteristics of what?
prostatic enlargement
Which medication classes does the nurse educate men on for the treatment of erectile dysfunction (ED)? All that apply
Tadalafil
Medications can be prescribed for the treatment of premature ejaculation? select all that apply
selective serotonin reuptake inhibitor (SSRI) antidepressants
Causes of male infertility ( select all that apply)
Low sperm count
obstruction in the shaft
Uterine prolapse is cause by relaxation of what ?
cardinal ligaments
Endometriosis is a condition in ... what ?
tissue similar to the lining of the uterus grows outside the uterus