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69 notecards = 18 pages (4 cards per page)

Viewing:

Microbial Diseases of the Cardio & Lymph System

front 1

Lymph nodes contain:

back 1

  • Macrophages
  • B cells
  • T cells

front 2

Sepsis

back 2

systemic inflammatory response

front 3

Septicema

back 3

pathogens/toxins in blood

front 4

Severe sepsis

back 4

sepsis + decreased blood pressure

front 5

Septic shock

back 5

sepsis + uncontrollable decreased blood pressure

front 6

Lymphangitis

back 6

  • Inflammed lymph vessels
  • accompany septicemia & septic shock

front 7

gram-NEGATIVE sepsis (ENDOtoxins)

back 7

  • septic shock
  • ENDOTOXINS - decrease blood pressure
  • antibiotics can worsen

front 8

Treatment for gram-NEGATIVE sepsis

back 8

protein C (anti-coagulant)

front 9

gram-POSITIVE sepsis (EXOtoxins)

back 9

Nosocomial infections

  • antibiotic-resistant

front 10

nosocomial infections

back 10

  • S. aureus
  • S. pyogenes
  • S. agalactiae (group B strep)
  • E. faecalis

front 11

Puerperal Sepsis (Childbirth Fever)

back 11

S. pyogenes

front 12

Bacterial infections of the heart

back 12

  • Endocarditis
  • Subacute bacterial endocarditis
  • Acute bacterial endocarditis
  • Pericarditis

front 13

Endocarditis

(inner layer of heart)

back 13

Inflammation of the endocardium

front 14

Acute Bacterial Endocarditis

back 14

S. aureus

  • from mouth

front 15

Sub-acute Bacterial Endocarditis

back 15

Strep

  • from mouth

front 16

Pericarditis

back 16

Strep

front 17

Rheumatic fever is an autoimmune complication of

back 17

S. pyogenes infections (strep throat)

  • inflammed heart valves

front 18

Tularemia

"rabbit fever"

back 18

Francisella tularensis

  • zoonosis (rabbits/deer)

front 19

Tularemia is transmitted by:

back 19

deer fly (vector)

front 20

Brucellosis

"undulant fever"

back 20

Brucella

  • grow in phagocytes
  • fever spikes each evening

front 21

Brucellosis is transmitted via

back 21

milk or direct contact with infected animal

front 22

Brucellosis:

  • B. abortus

back 22

elk, bison, cows

front 23

Brucellosis:

  • B. suis

back 23

swine

front 24

Brucellosis:

  • B. melitensis

back 24

goats, sheep, camels

front 25

Anthrax

back 25

Bacillus anthracis

  • found in soil (aerobe)
  • cattle routinely vaccinated

front 26

Gastrointestinal (GI) anthrax

back 26

  • ingest bad food
  • 50% mortality

front 27

Inhalation (pulmonary) anthrax

back 27

  • inhale endospores
  • 100% mortality

front 28

Gas gangrene

back 28

Clostridium perfingens

  • grows in necrotic tissue

front 29

ischemia

back 29

loss of blood supply to tissue

front 30

Necrosis

back 30

death of tissue

front 31

Gangrene

back 31

death of soft tissue

front 32

Systemic Diseases caused by bites & scratches

back 32

  • Bacteroides
  • Bartonella henselae
  • Clostridium
  • Fusobacterium
  • Pasturella multocida

front 33

Bartonella henselae

back 33

Cat Scratch Disease

front 34

Vector- transmitted Diseases:

  • Reservoir: Rodents
  • Vector: Arthropods (tick, flea)

back 34

  • Plague
  • Relapsing fever
  • Lyme disease
  • Typhus

front 35

Plague

back 35

Yersinia pestis

front 36

Bubonic plague

back 36

bacterial growth in blood & lymph

front 37

Septicemia plague

back 37

septic shock

front 38

Pneumonic plague

back 38

bacteria in the lungs

front 39

Relapsing Fever

back 39

Borrelia

  • ticks

front 40

T/F: successive relapses are less severe in Relapsing Fever?

back 40

True

front 41

Lyme Disease

back 41

Borrelia burgdorferi

  • tick (vector)

front 42

Lyme Disease:

3 phases of symptoms

back 42

  1. Bull's-eye rash
  2. encephalitis, irregular heartbeat
  3. arthritis

front 43

Typhus

back 43

Rickettsia

  • obligate parasites

front 44

Epidemic Typhus

back 44

R. prowazekii

  • louse feces rub in wound

front 45

Endemic Murine Typhus

back 45

R. typhi

front 46

Rocky Mountain Spotted Fever

back 46

R. rickettsii

  • rash on PALMS & SOLES of hands & feet

front 47

Viral Diseases of the Cardio & Lymph System:

back 47

  • Burkitt's Lymphoma
  • Infectious Mono
  • CMV
  • Chikungunya Fever
  • Yellow Fever
  • Dengue
  • Marbug Fever
  • Ebola
  • Lassa Fever
  • Hanta Pulmonary Syndrome

front 48

What 2 viruses are caused by the EB virus (HHV-4)

back 48

  • Burkitt's Lymphoma
  • Mono

front 49

Burkitt's Lymphoma

back 49

Epstein-Barr (EB) virus (HHV-4)

  • nasopharyngeal cancer
  • cancer in patients with Malaria or AIDS

front 50

Burkitt's Lymphoma cancer in immuno-suppressed patients with:

back 50

  • AIDS
  • Malaria

front 51

Mononucleosis (Mono)

back 51

Epstein-Barr (EB) virus (HHV-4)

  • transmitted via saliva

front 52

Cytomegalovirus - CMV

back 52

HHV-5

  • cells swell (WBC)

front 53

What are ways Cytomegalovirus is transmitted

back 53

  • across the placenta (causes mental retardation)
  • sex
  • blood
  • transplanted tissue

front 54

VIRAL Hemorrhagic Fevers:

back 54

  • Yellow
  • Dengue
  • Marburg
  • Ebola
  • Lassa
  • Argentine & Bolivian
  • Hantavirus

front 55

Viral Hemorrhagic Fevers:

Yellow Fever & Dengue

back 55

Abroviruses

  • transmitted via arthropods

front 56

Viral Hemorrhagic Fevers:

Marburg, Ebola, Lassa, Argentine, Bolivian, Whitewater Arroyo:

back 56

Filovirus & Arenavirus

  • contact w/ blood

front 57

Viral Hemorrhagic Fevers:

Hantavirus

back 57

Bunyavirus

  • inhalation of rodent excretions

front 58

Protozoan Diseases of the Cardio & Lymph System:

back 58

  • Chaga's Disease
  • Toxoplasmosis
  • Malaria

front 59

Chaga's Disease (American Trypanosomiasis)

back 59

T. cruzi

  • kissing bug

front 60

Toxoplasmosis

back 60

T. gondii

front 61

Toxoplasmosis is transmitted by

back 61

  • bad food
  • contact w/ cat feces

front 62

Congenital infection of Toxoplasmosis

back 62

  • stillbirth
  • neurological damage

front 63

Malaria

back 63

Plasmodium (protozoa parasite)

  • P. vivax
  • P.ovale
  • P. malariae
  • P. falciparum

front 64

Plasmodium - 4 forms

(malaria)

back 64

  • P. vivax
  • P.ovale
  • P. malariae
  • P. falciparum

front 65

The host & vector of Malaria

back 65

Anopheles MOSQUITO

*control with bed nets

front 66

Prevention (prophylaxis) of Malaria

back 66

  • Chloroquine
  • Malarone
  • Mefloquine

front 67

Treatment for Malaria

back 67

Artemisin

front 68

Bacterial Biological Weapons

back 68

  • Bacillus
  • Brucella
  • Chlaymdia
  • Clostridium
  • Francisella
  • Rickettsia
  • Shigella
  • Vibrio
  • Yersinia

front 69

Viral Biological Weapons

back 69

  • Polio
  • Measles
  • Encephalitis
  • Hemorrhagic fevers
  • Influenza A
  • Monkeypox
  • Niphrah
  • Smallpox
  • Yellow Fever