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genetics exam 3 (quizzes)

front 1

Which of the following are classified as pyrimidines?

back 1

thymine and cytosine

front 2

What type of bond is formed between the hydroxyl group of one nucleotide and the phosphate group of an adjacent nucleotide, forming the sugar-phosphate backbone of DNA?

back 2

phosphodiester bond

front 3

What types of bonds are formed between complementary DNA bases?

back 3

hydrogen bonds

front 4

Based on the following replication bubble, which of these statements is true?

back 4

W and Y are leading strands, X and Z are lagging strands

front 5

In E. coli, replication begins at which chromosome site?

back 5

oriC

front 6

What is the DNA replication fork?

back 6

It is the site where the DNA helix opens to two single DNA strands.

front 7

Okazaki fragments form on the lagging strand during DNA replication.

back 7

True

front 8

DNA replication in eukaryotes

back 8

initiates at multiple origins

front 9

DNA replication proceeds

back 9

semiconservatively

front 10

DNA replication occurs by adding

back 10

dNTPs to the 3′ end of the daughter strand

front 11

What are two distinguishing features of RNA?

back 11

RNA has a ribose sugar and uracil nitrogenous base.

front 12

What is the role of a promoter region of a gene?

back 12

Recruit transcription factors that form the initiation complex.

front 13

Which region(s) of a gene are not found within the mRNA transcript?

back 13

promoter and termination region

front 14

ou want to design a drug that prevents transcription of eukaryotic mRNAs but does not affect transcription of other RNAs. What enzyme would you target?

back 14

RNA polymerase II

front 15

Which of the following is part of a DNA molecule?

back 15

Promoter

front 16

Which enzyme is required to initiate 5′ capping of eukaryotic mRNA transcripts by removing the terminal phosphate group?

back 16

guanylyl transferase

front 17

Which of the following bacterial RNA polymerase subunits is found in the holoenzyme, but not the core enzyme?

back 17

σ (sigma)

front 18

What is the general name for the components of the spliceosome, which removes introns from mRNAs?

back 18

small nuclear ribonucleoproteins

front 19

What are catalytically active RNAs that can activate processes such as self-splicing?

back 19

ribozymes

front 20

What is the purpose of alternative splicing in eukaryotic cells?

back 20

Produce multiple polypeptide sequences from a single primary transcript.