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Viruses, viroids, and prions

1.

Viruses possess genetic material comprised of

DNA or RNA

2.

A double-stranded, enveloped DNA virus that contains reverse transcriptase belongs to which family

hepadnaviridae

3.

which of these processes of viral multiplication is most likely to damage the host cell?

release of viruses

4.

members of adenoviridae cause

the common cold

5.

which of the following are possible strategies for treating viral infection

blocking viral attachment to host cell receptors

blocking uncoating of the viruse after entry

blocking insertion of viral DNA into the host cell chromosomes

blocking biosynthesis of viral nucleic acids

ALL THE ABOVE

6.

which method cannot be used to culture viruses in a lab

nutrient agar culture media

7.

cell lines derived from transformed (cancerous) cells are called

continuous cell lines

8.

an example of a latent virus infection is

shingles

9.

during the bacteriophage lysogenic cycle

phage DNA is inserted into the host chromosome

10.

a virus may contain any of any of the following except

ribosomes

11.

after the attachment and entry of a virus into a host cell, what is the next step in the multiplication of animal viruses

uncoating

12.

viruses that use RNA as a template for transcribing DNA include

retroviridae

13.

in polio virus replication, the function of the antisense (-strand) RNA is to

serve as a template for the production of sense (+strand) RNA

14.

which of the following statements about spikes is false

they are used for penetration

15.

all of the following are RNA viruses except

hepatitis B virus

16.

which of the following is NOT used as a criterion to classify viruses

biochemical tests

17.

which of the following statements provides the most significant support for the idea that viruses are nonliving chemicals

they cannot reproduce themselves outside host

18.

which of the following is NOT a method of culturing viruses

in culture media

19.

bacteriophages and animal viruses do NOT differ significantly in which one of the following steps

biosynthesis

20.

a clear area against a confluent "lawn" of bacteria is called a

plaque

21.

the definition of lysogeny is

phage DNA is incorporated into host cell DNA

22.

continuous cell lines differ from primary cell lines in taht

continuous cell lines can be maintained through an indefinite number of generations

23.

a viroid is

a nonenveloped, infectious piece of RNA

24.

a persistent infection is an infection in which

the disease process occurs gradually over a long period

25.

which of the following would be the first step in biosynthesis of a virus with a -strand of RNA

synthesis of double-stranded RNA from an RNA template

26.

the most common route of accidental AIDS transmission of health care workers is

needlestick

27.

an infectious protein is a

prion

28.

some viruses, such as human herpesvirus 1 infect a cell without causing symptoms; these are called

latent viruses

29.

an enveloped is acquired during which of the following steps

release

30.

the following steps occur during multiplication of retroviruses. what is the fourth step

synthesis of double-stranded DNA

31.

viruses are considered obligatory intracellular parasites because

they require a host cell in order to multiply

32.

characteristics of viruses

contain either DNA or RNA

contain protein coat

multiply inside living cells

causes specialized structures to transfer nucleic acids to other cells

lack enzymes for protein synthesis and ATP generation

33.

define host range

the spectrum of host cells the virus can infect

34.

what is a bacteriophage

viruses that infect bacteria

35.

an infectious viral particle composed of nucleic acid and surrounded by a protein coat is

a virion

36.

caspid

protein coat which protects the nucleic acid of a virus

37.

capsomeres

protein subunits caspids are composed of

38.

helical viruses

long rods, may be rigid of flexible

ebola and rabies

39.

polyhedral

many-sized viruses

40.

enveloped viruses

roughly spherical. caspid is covered by an envelop

influenza virus

41.

complex virus

complicated structure

bacteriophage

42.

nonenveloped virus

caspid aren't covered by an envelope

43.

taxonomy of viruses

virus - genus names

viridae - family names

44.

viral species

viruses sharing the same genetic info and ecological niche

45.

plaques

number of clearings

46.

Plaque-forming units

concentrations of viral suspensions measured by the number of plaques

47.

where do they grow animal viruses in the lab

in living animals

in embryonated eggs

in cell cultures

48.

cell deterioration is known as

cytopathic effect

49.

adenoviridae

mastadenovirus

causes various respiratory infections

50.

papovaviridae

papillomavirus

warts and cervical and anal cancer

51.

poxviridae

molluscipoxvirus

smallpox and cowpox

52.

herpesviridae

simplexvirus (HHV-1), varicellovirus (HHV-3)

fever blisters, chicken pox, shingles, etc

53.

hepadnavirus

hepatitis B virus

54.

picornaviridae

hepatitis A virus

55.

togaviridae

rubivirus

56.

rhabdoviridae

causes rabies and various animal diseases

57.

filoviridae

enveloped, helical viruses

ebola

58.

paramyxoviridae

morbillivirus

measles virus

59.

orthomyxoviridae

influenza A, B, and C viruses

60.

retroviridae

oncoviruses

leukemia and tumors

61.

what are the two alternative mechanisms of bacteriophage multiplication

lytic cylce and lysogenic cycle

62.

lytic cycle

end with lysis and death of host cell

63.

lysogenic cycle

host cell remains alives

64.

persistent viral infection

occurs gradually over a long period

65.

latent infection

infection of the skin which produces cold sores.

66.

latent and persistent viral infections

67.

positive stranded RNA virus

can synthesize proteins

68.

negative stranded RNA virus

cannot be synthesized