5 Radreview Biological (102)
The effects of radiation on biologic material depend on several factors. If a quantity of radiation is delivered to a body over a long period of time, the effect
A will be greater than if it is delivered all at one time
B will be less than if it is delivered all at one time
C has no relation to how it is delivered in time
D solely depends on the radiation quality
B will be less than if it is delivered all at one time
Sources of natural background radiation contributing to whole-body radiation dose include
dental x-rays
terrestrial radionuclides
internal radionuclides
A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3
C 2 and 3 only
In the production of Bremsstrahlung radiation
A
the
incident photon ejects an inner-shell tungsten electron
B
the incident photon is deflected, with resulting energy
loss
C
the incident electron ejects an inner-shell tungsten
electron
D
the incident electron is deflected, with
resulting energy loss
D the incident electron is deflected, with resulting energy loss
What is used to account for the differences in tissue sensitivity to ionizing radiation when determining effective dose E?
Tissue weighting factors (W t )
Radiation weighting
factors (W r )
Absorbed dose
A
1 only
B
1 and 2 only
C
2 and 3
only
D
1, 2, and 3
A 1 only
Diagnostic x-radiation may be correctly described as
A
low
energy, low LET
B
low energy, high LET
C
high
energy, low LET
D
high energy, high LET
A low energy, low LET
Somatic effects resulting from radiation exposure can
have possible consequences on the exposed individual
have
possible consequences on future generations
cause temporary infertility
A
1 only
B
1 and 3 only
C
2 and 3
only
D
1, 2, and 3
B 1 and 3 only
Which interaction between x-ray photons and matter involves partial
transfer of the incident photon energy to the involved
atom?
A
Photoelectric effect
B
Compton scattering
C
Coherent scattering
D
Pair production
B Compton scattering
Factors that contribute to the amount of scattered radiation produced include
radiation quality
field size
grid ratio
A
1 only
B
1 and 2 only
C
2 and 3
only
D
1, 2, and 3
B 1 and 2 only
The interaction between x-ray photons and matter pictured in Figure A is associated with
Figure A.
1.
high-energy x-ray
photons.
2.
ionization.
3.
characteristic
radiation.
A
1 only
B
1 and 2 only
C
1 and 3 only
D
2 and 3 only
D 2 and 3 only
Stochastic effects of radiation include
A
blood changes
B
genetic alterations
C
cataractogenesis
D
reduced fertility
B
genetic alterations
All the following radiation-exposure responses exhibit a nonlinear
threshold dose–response relationship except
A
skin erythema
B
hematologic depression
C
radiation lethality
D
leukemia
D leukemia
What is used to account for the differences in ionizing
characteristics of various radiations, when determining their effect
on biologic material?
1. Radiation weighting factors ( W r
)
2. Tissue weighting factors ( W t )
3. Absorbed
dose
A
1 only
B
1 and 2 only
C
2 and 3
only
D
1, 2, and 3
A 1 only
The law of Bergonié and Tribondeau states that cells are more radiosensitive if they are
highly proliferative
highly differentiated
immature
A
1 only
B
1 and 2 only
C
1 and 3 only
D
1, 2, and 3
C 1 and 3 only
Which of the following types of radiation is (are) considered electromagnetic?
X-ray
Gamma
Beta
A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3
B
1 and 2 only
Which of the following is (are) possible long-term somatic effects of radiation exposure?
Blood changes
Cataractogenesis
Embryologic effects
A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3
C 2 and 3 only
The dose of radiation that will cause a noticeable skin reaction is
referred to as the
A
LET
B
SSD
C
SED
D
SID
C SED
Which of the following radiation exposure responses exhibit a
nonlinear threshold dose-response relationship?
1. Skin
erythema
2. Hematologic depression
3.
Lethality
A
1 only
B
1 and 2 only
C
2
and 3 only
D
1, 2, and 3
D 1, 2, and 3
Which of the following has(have) been identified as source(s) of radon exposure?
Indoors, in houses
Smoking cigarettes
Radiology departments
A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3
B 1 and 2 only
The photoelectric effect is more likely to occur with
absorbers having a high Z number
high-energy incident
photons
positive contrast media
A
1 and 2 only
B
1 and 3 only
C
2 and
3 only
D
1, 2, and 3
B
1 and 3 only
Stochastic effects of radiation are those that
have a threshold
may be described as “all-or-nothing”
effects
are late effects
A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3
C
2 and 3 only
Which of the dose–response curves seen in Figure 3–4 represents possible genetic effects of ionizing radiation?
A
Dose–response curve A
B
Dose–response curve
B
C
Dose–response curve C
D
None of these
A Dose–response curve A
The principal late effects of ionizing radiation on humans include
local tissue damage
genetic effects
malignant disease
A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3
C 2 and 3 only
In radiation protection, the product of absorbed dose and the correct
modifying factor (rad × QF) is used to determine
A
roentgen
(C/kg)
B
rem (Sv)
C
curie (Cu)
D
radiation quality
B rem (Sv)
Early symptoms of acute radiation syndrome include
leukopenia
nausea and vomiting
cataracts
A
1 and 2 only
B
2 only
C
1 and 3 only
D
2 and 3 only
A 1 and 2 only
LET is best defined as
a method of expressing radiation quality
a measure of the
rate at which radiation energy is transferred to soft tissue
absorption of polyenergetic radiation
A
1 only
B
1 and 2 only
C
1 and 3 only
D
1, 2, and 3
B 1 and 2 only
Which of the following cells is the least
radiosensitive?
A
Myelocytes
B
Myocytes
C
Megakaryocytes
D
Erythroblast
B Myocytes
Which of the following types of adult tissues is (are) relatively
insensitive to radiation exposure?
1. Muscle tissue
2. Nerve
tissue
3. Epithelial tissue
A
1 only
B
1 and
2 only
C
2 and 3 only
D
1, 2, and 3
B 1 and 2 only
If 600 rad or more is received as a whole-body dose in a short period
of time, certain symptoms will occur; these are referred to
as
A
short-term effects.
B
long-term effects.
C
lethal dose.
D
acute radiation syndrome.
D
acute radiation syndrome.
Which of the following dose-response curve characteristics represent
genetic and some somatic responses to radiation?
1.
Linear
2. Nonthreshold
3. Sigmoidal
A
1 only
B
1 and 2 only
C
1 and 3 only
D
1, 2,
and 3
B 1 and 2 only
Which of the dose-response curves pictured in Figure A illustrate(s) a linear threshold dose effect?
Figure A.
1.
Curve number 1
2.
Curve number
2
3.
Curve number 3
A
1 only
B
3 only
C
2 and 3 only
D
1, 2, and 3
B 3 only
Which of the following is (are) considered especially radiosensitive tissues?
Bone marrow
Intestinal crypt cells
Erythroblasts
A
1 and 2 only
B
1 and 3 only
C
2 and
3 only
D
1, 2, and 3
D 1, 2, and 3
Which of the following anomalies is (are) possible if an exposure dose of 40 rad (400 mGy) were delivered to a pregnant uterus in the third week of pregnancy?
Skeletal anomaly
Organ anomaly
Neurologic anomaly
A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3
B 1 and 2 only
Which of the following statements is (are) true with respect to the
dose–response curve shown in Figure 3–6?The quantity of radiation is
directly related to the dose received.
No threshold is required
for effects to occur.
A minimum amount of radiation is required
for manifestation of effects.
A
1 only
B
1 and 2 only
C
1 and 3 only
D
2 and 3 only
C 1 and 3 only
The skin response to radiation exposure that appears as hair loss is
known as
A
dry desquamation
B
moist desquamation
C
erythema
D
epilation
D epilation
If a quantity of radiation is delivered to a body over a short period
of time, its effect
A
will be greater than if it were
delivered over a long period of time.
B
depends solely on
the distance factor.
C
has no relation to how it is
delivered in time.
D
depends solely on the radiation quantity.
A
will be greater than if it were delivered over a long period
of time.
The interaction between ionizing radiation and the target molecule
that is most likely to occur is the
A
direct effect
B
indirect effect
C
target effect
D
random effect
B
indirect effect
The target theory applies to
A
spermatagonia
B
oocytes
C
lymphocytes
D
DNA molecules
D DNA molecules
The classifications of acute radiation syndrome include all the
following except
A
central nervous system
B
gastrointestinal
C
neonatal
D
hematologic
C neonatal
Which of the following interactions between x-ray photons and matter
is most responsible for patient dose?
A
The photoelectric
effect
B
Compton scatter
C
Classic scatter
D
Thompson scatter
A The photoelectric effect
Which of the following are considered most
radiosensitive?
A
Lymphocytes
B
Ova
C
Neurons
D
Myocytes
A
Lymphocytes
For exposure to 1 rad of each of the following ionizing radiations,
which would result in the greatest dose to the
individual?
A
External source of 1-MeV x-rays
B
External source of diagnostic x-rays
C
Internal source of alpha particles
D
External
source of beta particles
C
Internal source of alpha particles
Which interaction between x-ray photons and matter results in total
absorption of the incident photon?
A
Photoelectric effect
B
Compton scattering
C
Coherent scattering
D
Pair production
A
Photoelectric effect
Which of the following expresses the gonadal dose that, if received
by every member of the population, would be expected to produce the
same total genetic effect on that population as the actual doses
received by each of the individuals?
A
Genetically
significant dose
B
Somatically significant dose
C
Maximum permissible dose
D
Lethal dose
A
Genetically significant dose
What is the relationship between LET and RBE?
A
As LET
increases, RBE increases.
B
As LET increases, RBE
decreases.
C
As LET decreases, RBE increases.
D
There is no direct relationship between LET and RBE.
A As LET increases, RBE increases.
Which of the following cell types has the greatest radiosensitivity
in the adult human?
A
Nerve cells
B
Muscle cells
C
Spermatids
D
Lymphocytes
D
Lymphocytes
The term used to describe the gradual decrease in exposure rate as an
x-ray beam passes through matter is
A
attenuation
B
absorption
C
scattered radiation
D
secondary radiation
A
attenuation
What is the effect on RBE as LET increases?
A
As LET
increases, RBE increases.
B
As LET increases, RBE
decreases.
C
As LET increases, RBE stabilizes.
D
LET has no effect on RBE.
A
As LET increases, RBE increases.
The dose–response curve that appears to be valid for genetic and some somatic effects is the
linear
nonlinear
nonthreshold
A
1 only
B
1 and 3 only
C
2 and 3 only
D
1, 2, and 3
B 1 and 3 only
Late radiation-induced somatic effects include
thyroid cancers
cataractogenesis
skin cancers
A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3
D 1, 2, and 3
Which of the following defines the gonadal dose that, if received by
every member of the population, would be expected to produce the same
total genetic effect on that population as the actual doses received
by each of the individuals?
A
Genetically significant dose
B
Somatically significant dose
C
Maximum
permissible dose
D
Lethal dose
A Genetically significant dose
How are LET and biologic response related?
A
They are
inversely related.
B
They are directly related.
C
They are related in a reciprocal fashion.
D
They are unrelated.
B
They are directly related.
Which of the following statements regarding the human gonadal cells is (are) true?
The female oogonia reproduce only during fetal life.
The
male spermatogonia reproduce continuously.
Both male and female
stem cells reproduce only during fetal life.
A
1 only
B
2 only
C
1 and 2 only
D
3 only
C
1 and 2 only
In 1906, Bergonié and Tribondeau theorized that undifferentiated cells are highly radiosensitive. Which of the following is (are) characteristic(s) of undifferentiated cells?
Young cells
Highly mitotic cells
Precursor cells
A
1 only
B
1 and 2 only
C
1 and 3 only
D
1, 2, and 3
D
1, 2, and 3
Which of the following terms refers to the period between conception
and birth?
A
Gestation
B
Congenital
C
Neonatal
D
In vitro
A
Gestation
The interaction between x-ray photons and matter shown in Figure 3–1
is associated withtotal energy transfer from photon to
electron
an outer-shell electron
Compton scatter
A
1 only
B
1 and 2 only
C
1 and 3
only
D
2 and 3 only
A 1 only
Biologic material is most sensitive to radiation exposure under which
of the following conditions?
A
Anoxic
B
Hypoxic
C
Oxygenated
D
Deoxygenated
C
Oxygenated
Examples of stochastic effects of radiation exposure include
radiation-induced malignancy
genetic effects
leukemia
A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3
D 1, 2, and 3
The symbols 130/56 Ba and 138/56 Ba are examples of which of the
following?
A
Isotopes
B
Isobars
C
Isotones
D
Isomers
A Isotopes
Which of the following is (are) considered long-term somatic effect(s) of exposure to ionizing radiation?
Life-span shortening
Carcinogenesis
Cataractogenesis
A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3
D
1, 2, and 3
Which of the following radiation-induced conditions is most likely to
have the longest latent period?
A
Leukemia
B
Temporary infertility
C
Erythema
D
Acute radiation lethality
A
Leukemia
Biologic material is least sensitive to irradiation under which of
the following conditions?
A
Anoxic
B
Hypoxic
C
Oxygenated
D
Hyperbaric
A Anoxic
The effects of radiation on biologic material depend on several
factors. If a large quantity of radiation is delivered to a body over
a short period of time, the effect
A
will be greater than if
it were delivered in increments
B
will be less than if it
were delivered in increments
C
has no relation to how it is
delivered in time
D
solely depends on the radiation quality
A will be greater than if it were delivered in increments
Which type of dose–response relationship represents radiation-induced
leukemia and genetic effects?
A
Linear, threshold
B
Nonlinear, threshold
C
Linear, nonthreshold
D
Nonlinear, nonthreshold
C Linear, nonthreshold
Which of the following tissues or organs is the most
radiosensitive?
A
Rectum
B
Esophagus
C
Small bowel
D
Central nervous system (CNS)
C Small bowel
What is (are) the major effect(s) of deoxyribonucleic acid (DNA) irradiation?
Malignant disease
Chromosome aberration
Cell death
A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3
D 1, 2, and 3
Which of the following is (are) used to account for the differences in tissue characteristics when determining effective dose to biologic material?
Tissue weighting factors (W t )
Radiation weighting factors
(W r )
Absorbed dose
A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3
A 1 only
Types of secondary radiation include1. scattered.
2. leakage.
3. primary.
A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3
B 1 and 2 only
Examples of late effects of ionizing radiation on humans include
leukemia
local tissue damage
malignant disease
A
1 only
B
1 and 2 only
C
1 and 3 only
D
1, 2, and 3
D 1, 2, and 3
Major effect(s) of irradiation of macromolecules include(s)
point lesions
cross-linking
main-chain scission
A
1 only
B
1 and 2 only
C
1 and 3 only
D
1, 2, and 3
D
1, 2, and 3
Occupational exposure received by the radiographer is mostly
from
A
Compton scatter
B
the photoelectric effect
C
coherent scatter
D
pair production
A Compton scatter
The most radiosensitive portion of the GI tract is
the
A
upper esophagus
B
stomach
C
small bowel
D
cecum and ascending colon
C small bowel
Somatic effects of radiation refer to effects that are
manifested
A
in the descendants of the exposed individual
B
during the life of the exposed individual
C
in
the exposed individual and his or her descendants
D
in the
reproductive cells of the exposed individual
B during the life of the exposed individual
Which of the following cell types has the lowest
radiosensitivity?
A
Nerve cells
B
Muscle cells
C
Spermatids
D
Lymphocytes
A Nerve cells
Irradiation of macromolecules in vitro can result in
main-chain scission
cross-linking
point lesions
A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3
D 1, 2, and 3
Possible responses to irradiation in utero include
spontaneous abortion
congenital anomalies
childhood malignancies
A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3 only
D 1, 2, and 3 only
The skin response to radiation exposure, which appears as reddening
of the irradiated skin area, is known as
A
dry desquamation
B
moist desquamation
C
erythema
D
epilation
C erythema
The photoelectric effect is an interaction between an x-ray photon
and
A
an inner-shell electron
B
an outer-shell
electron
C
a nucleus
D
another photon
A an inner-shell electron
Which interaction between ionizing radiation and the target molecule
involves formation of a free radical?
A
Direct effect
B
Indirect effect
C
Target effect
D
Random effect
B Indirect effect
Which of the dose–response curve(s) shown in Figure 3–2 illustrate(s)
a linear threshold response to radiation exposure?Dose–response curve
A
Dose–response curve B
Dose–response curve C
A
1 only
B
2 only
C
1 and
2 only
D
2 and 3 only
B 2 only
The radiation dose to an individual depends on which of the following?
Type of tissue interaction(s)
Quantity of radiation
Biologic differences
A
1 only
B
1 and 2 only
C
1 and 3 only
D
1, 2, and 3
D 1, 2, and 3
Which of the following types of adult tissue is (are) comparatively insensitive to effects of ionizing radiation?
Epithelial tissue
Nerve tissue
Muscle tissue
A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3
C
2 and 3 only
What is the term used to describe x-ray photon interaction with
matter and the transference of part of the photon's energy to
matter?
A
Absorption
B
Scattering
C
Attenuation
D
Divergence
B Scattering
How do fractionation and protraction affect radiation dose effects?
They reduce the effect of radiation exposure.
They permit
cellular repair.
They allow tissue recovery.
A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3
D
1, 2, and 3
Which acute radiation syndrome requires the largest exposure before
any effects become apparent?
A
Hematopoietic
B
Gastrointestinal
C
Central nervous system
(CNS)
D
Skeletal
C
Central nervous system (CNS)
Linear energy transfer (LET) may be best described as
A
the
amount of energy delivered per distance traveled in tissue.
B
the unit of absorbed dose.
C
radiation
equivalent man.
D
radiation absorbed dose.
A
the amount of energy delivered per distance traveled in tissue.
If a quantity of radiation is delivered to a body in a short period
of time, its effect
A
will be greater than if it were
delivered over a long period of time.
B
will be less than
if it were delivered over a long period of time.
C
has no
relation to how it is delivered in time.
D
is solely
dependent on the radiation quality.
A
will be greater than if it were delivered over a long period
of time.
Which of the following contributes most to patient
dose?
A
The photoelectric effect
B
Compton
scatter
C
Classical scatter
D
Thompson scatter
A
The photoelectric effect
Irradiation of water molecules within the body and their resulting
breakdown is termed
A
epilation
B
radiolysis
C
proliferation
D
repopulation
B
radiolysis
The symbols 130/56 Ba and 138/56 Ba are examples of which of the
following?
A
Isotopes
B
Isobars
C
Isotones
D
Isomers
A Isotopes
Which of the dose–response curves shown in Figure 6–2 illustrate(s)
illustrates a linear relationship between dose and response?Curve
number 1
Curve number 2
Curve number 3
A
1 only
B
2 only
C
1 and 3 only
D
1, 2, and 3
C 1 and 3 only
The effect of ionizing radiation on tissue depends on which of the following?
Type of tissue interaction(s)
Amount of interactions
Biologic differences
A
1 and 2 only
B
1 and 3 only
C
2 and
3 only
D
1, 2, and 3
D
1, 2, and 3
Isotopes are atoms that have the same
A
mass number but a
different atomic number
B
atomic number but a different
mass number
C
mass number but a different neutron number
D
atomic number and mass number
B
atomic number but a different mass number
The effects of radiation on biologic material depend on several
factors. If a quantity of radiation is delivered to a body over a long
period of time, the effect
A
will be greater than if it were
delivered all at one time
B
will be less than if it were
delivered all at one time
C
has no relation to how it is
delivered in time
D
depends solely on the radiation quality
B
will be less than if it were delivered all at one time
Late or long-term effects of radiation exposure are generally
represented by which of the following dose-response
curves?
A
Linear threshold
B
Linear nonthreshold
C
Nonlinear threshold
D
Nonlinear nonthreshold
B
Linear nonthreshold
Which of the following factors can affect the amount or the nature of radiation damage to biologic tissue?
Radiation quality
Absorbed dose
Size of irradiated area
A
1 only
B
2 only
C
1 and 2 only
D
1, 2, and 3
D 1, 2, and 3
What is likely to occur if 25 rad is accidentally delivered to a
recently fertilized ovum?
A
Skeletal anomalies
B
CNS anomalies
C
Spontaneous abortion
D
Childhood malignancy
C
Spontaneous abortion
Which of the following cell types has the greatest
radiosensitivity?
A
Nerve cells
B
Muscle cells
C
Spermatids
D
Lymphocytes
D
Lymphocytes
Late effects of radiation, whose incidence is dose related and for
which there is no threshold dose, are referred to
as
A
nonstochastic
B
stochastic
C
chromosomal aberration
D
hematologic depression
B
stochastic
The x-ray interaction with matter that is responsible for the
majority of scattered radiation reaching the image receptor (IR)
is
A
the photoelectric effect
B
Compton scatter
C
classical scatter
D
Thompson scatter
B
Compton scatter
Which of the following ionizing radiations is described as having an
RBE of 1.0?
A
10 MeV protons
B
5 MeV alpha
particles
C
Diagnostic x-rays
D
Fast neutrons
C Diagnostic x-rays
Sources of natural background radiation exposure include
1. the
food we eat.
2. air travel.
3. medical and dental
x-rays.
A
1 only
B
1 and 2 only
C
2
and 3 only
D
1, 2, and 3
B 1 and 2 only
The late effects of radiation are considered to
have no threshold dose.
be directly related to dose.
occur within hours of exposure.
A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3
B
1 and 2 only