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5 Radreview Biological (102)

front 1

The effects of radiation on biologic material depend on several factors. If a quantity of radiation is delivered to a body over a long period of time, the effect

A will be greater than if it is delivered all at one time

B will be less than if it is delivered all at one time

C has no relation to how it is delivered in time

D solely depends on the radiation quality

back 1

B will be less than if it is delivered all at one time

front 2

Sources of natural background radiation contributing to whole-body radiation dose include

dental x-rays
terrestrial radionuclides
internal radionuclides

A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3

back 2

C 2 and 3 only

front 3

In the production of Bremsstrahlung radiation
A
the incident photon ejects an inner-shell tungsten electron
B
the incident photon is deflected, with resulting energy loss
C
the incident electron ejects an inner-shell tungsten electron
D
the incident electron is deflected, with resulting energy loss

back 3

D the incident electron is deflected, with resulting energy loss

front 4

What is used to account for the differences in tissue sensitivity to ionizing radiation when determining effective dose E?

Tissue weighting factors (W t )
Radiation weighting factors (W r )
Absorbed dose

A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3

back 4

A 1 only

front 5

Diagnostic x-radiation may be correctly described as
A
low energy, low LET
B
low energy, high LET
C
high energy, low LET
D
high energy, high LET

back 5

A low energy, low LET

front 6

Somatic effects resulting from radiation exposure can

have possible consequences on the exposed individual
have possible consequences on future generations
cause temporary infertility

A
1 only
B
1 and 3 only
C
2 and 3 only
D
1, 2, and 3

back 6

B 1 and 3 only

front 7

Which interaction between x-ray photons and matter involves partial transfer of the incident photon energy to the involved atom?
A
Photoelectric effect
B
Compton scattering
C
Coherent scattering
D
Pair production

back 7

B Compton scattering

front 8

Factors that contribute to the amount of scattered radiation produced include

radiation quality
field size
grid ratio

A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3

back 8

B 1 and 2 only

front 9

The interaction between x-ray photons and matter pictured in Figure A is associated with

Figure A.

1.
high-energy x-ray photons.
2.
ionization.
3.
characteristic radiation.
A
1 only
B
1 and 2 only
C
1 and 3 only
D
2 and 3 only

back 9

D 2 and 3 only

front 10

Stochastic effects of radiation include
A
blood changes
B
genetic alterations
C
cataractogenesis
D
reduced fertility

back 10

B
genetic alterations

front 11

All the following radiation-exposure responses exhibit a nonlinear threshold dose–response relationship except
A
skin erythema
B
hematologic depression
C
radiation lethality
D
leukemia

back 11

D leukemia

front 12

What is used to account for the differences in ionizing characteristics of various radiations, when determining their effect on biologic material?
1. Radiation weighting factors ( W r )
2. Tissue weighting factors ( W t )
3. Absorbed dose
A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3

back 12

A 1 only

front 13

The law of Bergonié and Tribondeau states that cells are more radiosensitive if they are

highly proliferative
highly differentiated
immature

A
1 only
B
1 and 2 only
C
1 and 3 only
D
1, 2, and 3

back 13

C 1 and 3 only

front 14

Which of the following types of radiation is (are) considered electromagnetic?

X-ray
Gamma
Beta

A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3

back 14

B
1 and 2 only

front 15

Which of the following is (are) possible long-term somatic effects of radiation exposure?

Blood changes
Cataractogenesis
Embryologic effects

A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3

back 15

C 2 and 3 only

front 16

The dose of radiation that will cause a noticeable skin reaction is referred to as the
A
LET
B
SSD
C
SED
D
SID

back 16

C SED

front 17

Which of the following radiation exposure responses exhibit a nonlinear threshold dose-response relationship?
1. Skin erythema
2. Hematologic depression
3. Lethality
A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3

back 17

D 1, 2, and 3

front 18

Which of the following has(have) been identified as source(s) of radon exposure?

Indoors, in houses
Smoking cigarettes
Radiology departments

A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3

back 18

B 1 and 2 only

front 19

The photoelectric effect is more likely to occur with

absorbers having a high Z number
high-energy incident photons
positive contrast media

A
1 and 2 only
B
1 and 3 only
C
2 and 3 only
D
1, 2, and 3

back 19

B
1 and 3 only

front 20

Stochastic effects of radiation are those that

have a threshold
may be described as “all-or-nothing” effects
are late effects

A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3

back 20

C
2 and 3 only

front 21

Which of the dose–response curves seen in Figure 3–4 represents possible genetic effects of ionizing radiation?

A
Dose–response curve A
B
Dose–response curve B
C
Dose–response curve C
D
None of these

back 21

A Dose–response curve A

front 22

The principal late effects of ionizing radiation on humans include

local tissue damage
genetic effects
malignant disease

A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3

back 22

C 2 and 3 only

front 23

In radiation protection, the product of absorbed dose and the correct modifying factor (rad × QF) is used to determine
A
roentgen (C/kg)
B
rem (Sv)
C
curie (Cu)
D
radiation quality

back 23

B rem (Sv)

front 24

Early symptoms of acute radiation syndrome include

leukopenia
nausea and vomiting
cataracts

A
1 and 2 only
B
2 only
C
1 and 3 only
D
2 and 3 only

back 24

A 1 and 2 only

front 25

LET is best defined as

a method of expressing radiation quality
a measure of the rate at which radiation energy is transferred to soft tissue
absorption of polyenergetic radiation

A
1 only
B
1 and 2 only
C
1 and 3 only
D
1, 2, and 3

back 25

B 1 and 2 only

front 26

Which of the following cells is the least radiosensitive?
A
Myelocytes
B
Myocytes
C
Megakaryocytes
D
Erythroblast

back 26

B Myocytes

front 27

Which of the following types of adult tissues is (are) relatively insensitive to radiation exposure?
1. Muscle tissue
2. Nerve tissue
3. Epithelial tissue
A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3

back 27

B 1 and 2 only

front 28

If 600 rad or more is received as a whole-body dose in a short period of time, certain symptoms will occur; these are referred to as
A
short-term effects.
B
long-term effects.
C
lethal dose.
D
acute radiation syndrome.

back 28

D
acute radiation syndrome.

front 29

Which of the following dose-response curve characteristics represent genetic and some somatic responses to radiation?
1. Linear
2. Nonthreshold
3. Sigmoidal
A
1 only
B
1 and 2 only
C
1 and 3 only
D
1, 2, and 3

back 29

B 1 and 2 only

front 30

Which of the dose-response curves pictured in Figure A illustrate(s) a linear threshold dose effect?

Figure A.

1.
Curve number 1
2.
Curve number 2
3.
Curve number 3

A
1 only

B
3 only

C
2 and 3 only

D
1, 2, and 3

back 30

B 3 only

front 31

Which of the following is (are) considered especially radiosensitive tissues?

Bone marrow
Intestinal crypt cells
Erythroblasts

A
1 and 2 only
B
1 and 3 only
C
2 and 3 only
D
1, 2, and 3

back 31

D 1, 2, and 3

front 32

Which of the following anomalies is (are) possible if an exposure dose of 40 rad (400 mGy) were delivered to a pregnant uterus in the third week of pregnancy?

Skeletal anomaly
Organ anomaly
Neurologic anomaly

A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3

back 32

B 1 and 2 only

front 33

Which of the following statements is (are) true with respect to the dose–response curve shown in Figure 3–6?The quantity of radiation is directly related to the dose received.
No threshold is required for effects to occur.
A minimum amount of radiation is required for manifestation of effects.

A
1 only

B
1 and 2 only

C
1 and 3 only

D
2 and 3 only

back 33

C 1 and 3 only

front 34

The skin response to radiation exposure that appears as hair loss is known as
A
dry desquamation
B
moist desquamation
C
erythema
D
epilation

back 34

D epilation

front 35

If a quantity of radiation is delivered to a body over a short period of time, its effect
A
will be greater than if it were delivered over a long period of time.
B
depends solely on the distance factor.
C
has no relation to how it is delivered in time.
D
depends solely on the radiation quantity.

back 35

A
will be greater than if it were delivered over a long period of time.

front 36

The interaction between ionizing radiation and the target molecule that is most likely to occur is the
A
direct effect
B
indirect effect
C
target effect
D
random effect

back 36

B
indirect effect

front 37

The target theory applies to
A
spermatagonia
B
oocytes
C
lymphocytes
D
DNA molecules

back 37

D DNA molecules

front 38

The classifications of acute radiation syndrome include all the following except
A
central nervous system
B
gastrointestinal
C
neonatal
D
hematologic

back 38

C neonatal

front 39

Which of the following interactions between x-ray photons and matter is most responsible for patient dose?
A
The photoelectric effect
B
Compton scatter
C
Classic scatter
D
Thompson scatter

back 39

A The photoelectric effect

front 40

Which of the following are considered most radiosensitive?
A
Lymphocytes
B
Ova
C
Neurons
D
Myocytes

back 40

A
Lymphocytes

front 41

For exposure to 1 rad of each of the following ionizing radiations, which would result in the greatest dose to the individual?
A
External source of 1-MeV x-rays
B
External source of diagnostic x-rays
C
Internal source of alpha particles
D
External source of beta particles

back 41

C
Internal source of alpha particles

front 42

Which interaction between x-ray photons and matter results in total absorption of the incident photon?
A
Photoelectric effect
B
Compton scattering
C
Coherent scattering
D
Pair production

back 42

A
Photoelectric effect

front 43

Which of the following expresses the gonadal dose that, if received by every member of the population, would be expected to produce the same total genetic effect on that population as the actual doses received by each of the individuals?
A
Genetically significant dose
B
Somatically significant dose
C
Maximum permissible dose
D
Lethal dose

back 43

A
Genetically significant dose

front 44

What is the relationship between LET and RBE?
A
As LET increases, RBE increases.
B
As LET increases, RBE decreases.
C
As LET decreases, RBE increases.
D
There is no direct relationship between LET and RBE.

back 44

A As LET increases, RBE increases.

front 45

Which of the following cell types has the greatest radiosensitivity in the adult human?
A
Nerve cells
B
Muscle cells
C
Spermatids
D
Lymphocytes

back 45

D
Lymphocytes

front 46

The term used to describe the gradual decrease in exposure rate as an x-ray beam passes through matter is
A
attenuation
B
absorption
C
scattered radiation
D
secondary radiation

back 46

A
attenuation

front 47

What is the effect on RBE as LET increases?
A
As LET increases, RBE increases.
B
As LET increases, RBE decreases.
C
As LET increases, RBE stabilizes.
D
LET has no effect on RBE.

back 47

A
As LET increases, RBE increases.

front 48

The dose–response curve that appears to be valid for genetic and some somatic effects is the

linear
nonlinear
nonthreshold

A
1 only
B
1 and 3 only
C
2 and 3 only
D
1, 2, and 3

back 48

B 1 and 3 only

front 49

Late radiation-induced somatic effects include

thyroid cancers
cataractogenesis
skin cancers

A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3

back 49

D 1, 2, and 3

front 50

Which of the following defines the gonadal dose that, if received by every member of the population, would be expected to produce the same total genetic effect on that population as the actual doses received by each of the individuals?
A
Genetically significant dose
B
Somatically significant dose
C
Maximum permissible dose
D
Lethal dose

back 50

A Genetically significant dose

front 51

How are LET and biologic response related?
A
They are inversely related.
B
They are directly related.
C
They are related in a reciprocal fashion.
D
They are unrelated.

back 51

B
They are directly related.

front 52

Which of the following statements regarding the human gonadal cells is (are) true?

The female oogonia reproduce only during fetal life.
The male spermatogonia reproduce continuously.
Both male and female stem cells reproduce only during fetal life.

A
1 only
B
2 only
C
1 and 2 only
D
3 only

back 52

C
1 and 2 only

front 53

In 1906, Bergonié and Tribondeau theorized that undifferentiated cells are highly radiosensitive. Which of the following is (are) characteristic(s) of undifferentiated cells?

Young cells
Highly mitotic cells
Precursor cells

A
1 only
B
1 and 2 only
C
1 and 3 only
D
1, 2, and 3

back 53

D
1, 2, and 3

front 54

Which of the following terms refers to the period between conception and birth?
A
Gestation
B
Congenital
C
Neonatal
D
In vitro

back 54

A
Gestation

front 55

The interaction between x-ray photons and matter shown in Figure 3–1 is associated withtotal energy transfer from photon to electron
an outer-shell electron
Compton scatter

A
1 only
B
1 and 2 only
C
1 and 3 only
D
2 and 3 only

back 55

A 1 only

front 56

Biologic material is most sensitive to radiation exposure under which of the following conditions?
A
Anoxic
B
Hypoxic
C
Oxygenated
D
Deoxygenated

back 56

C
Oxygenated

front 57

Examples of stochastic effects of radiation exposure include

radiation-induced malignancy
genetic effects
leukemia

A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3

back 57

D 1, 2, and 3

front 58

The symbols 130/56 Ba and 138/56 Ba are examples of which of the following?
A
Isotopes
B
Isobars
C
Isotones
D
Isomers

back 58

A Isotopes

front 59

Which of the following is (are) considered long-term somatic effect(s) of exposure to ionizing radiation?

Life-span shortening
Carcinogenesis
Cataractogenesis

A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3

back 59

D
1, 2, and 3

front 60

Which of the following radiation-induced conditions is most likely to have the longest latent period?
A
Leukemia
B
Temporary infertility
C
Erythema
D
Acute radiation lethality

back 60

A
Leukemia

front 61

Biologic material is least sensitive to irradiation under which of the following conditions?
A
Anoxic
B
Hypoxic
C
Oxygenated
D
Hyperbaric

back 61

A Anoxic

front 62

The effects of radiation on biologic material depend on several factors. If a large quantity of radiation is delivered to a body over a short period of time, the effect
A
will be greater than if it were delivered in increments
B
will be less than if it were delivered in increments
C
has no relation to how it is delivered in time
D
solely depends on the radiation quality

back 62

A will be greater than if it were delivered in increments

front 63

Which type of dose–response relationship represents radiation-induced leukemia and genetic effects?
A
Linear, threshold
B
Nonlinear, threshold
C
Linear, nonthreshold
D
Nonlinear, nonthreshold

back 63

C Linear, nonthreshold

front 64

Which of the following tissues or organs is the most radiosensitive?
A
Rectum
B
Esophagus
C
Small bowel
D
Central nervous system (CNS)

back 64

C Small bowel

front 65

What is (are) the major effect(s) of deoxyribonucleic acid (DNA) irradiation?

Malignant disease
Chromosome aberration
Cell death

A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3

back 65

D 1, 2, and 3

front 66

Which of the following is (are) used to account for the differences in tissue characteristics when determining effective dose to biologic material?

Tissue weighting factors (W t )
Radiation weighting factors (W r )
Absorbed dose

A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3

back 66

A 1 only

front 67

Types of secondary radiation include1. scattered.

2. leakage.

3. primary.
A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3

back 67

B 1 and 2 only

front 68

Examples of late effects of ionizing radiation on humans include

leukemia
local tissue damage
malignant disease

A
1 only
B
1 and 2 only
C
1 and 3 only
D
1, 2, and 3

back 68

D 1, 2, and 3

front 69

Major effect(s) of irradiation of macromolecules include(s)

point lesions
cross-linking
main-chain scission

A
1 only
B
1 and 2 only
C
1 and 3 only
D
1, 2, and 3

back 69

D
1, 2, and 3

front 70

Occupational exposure received by the radiographer is mostly from
A
Compton scatter
B
the photoelectric effect
C
coherent scatter
D
pair production

back 70

A Compton scatter

front 71

The most radiosensitive portion of the GI tract is the
A
upper esophagus
B
stomach
C
small bowel
D
cecum and ascending colon

back 71

C small bowel

front 72

Somatic effects of radiation refer to effects that are manifested
A
in the descendants of the exposed individual
B
during the life of the exposed individual
C
in the exposed individual and his or her descendants
D
in the reproductive cells of the exposed individual

back 72

B during the life of the exposed individual

front 73

Which of the following cell types has the lowest radiosensitivity?
A
Nerve cells
B
Muscle cells
C
Spermatids
D
Lymphocytes

back 73

A Nerve cells

front 74

Irradiation of macromolecules in vitro can result in

main-chain scission
cross-linking
point lesions

A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3

back 74

D 1, 2, and 3

front 75

Possible responses to irradiation in utero include

spontaneous abortion
congenital anomalies
childhood malignancies

A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3 only

back 75

D 1, 2, and 3 only

front 76

The skin response to radiation exposure, which appears as reddening of the irradiated skin area, is known as
A
dry desquamation
B
moist desquamation
C
erythema
D
epilation

back 76

C erythema

front 77

The photoelectric effect is an interaction between an x-ray photon and
A
an inner-shell electron
B
an outer-shell electron
C
a nucleus
D
another photon

back 77

A an inner-shell electron

front 78

Which interaction between ionizing radiation and the target molecule involves formation of a free radical?
A
Direct effect
B
Indirect effect
C
Target effect
D
Random effect

back 78

B Indirect effect

front 79

Which of the dose–response curve(s) shown in Figure 3–2 illustrate(s) a linear threshold response to radiation exposure?Dose–response curve A
Dose–response curve B
Dose–response curve C

A
1 only

B
2 only

C
1 and 2 only

D
2 and 3 only

back 79

B 2 only

front 80

The radiation dose to an individual depends on which of the following?

Type of tissue interaction(s)
Quantity of radiation
Biologic differences

A
1 only
B
1 and 2 only
C
1 and 3 only
D
1, 2, and 3

back 80

D 1, 2, and 3

front 81

Which of the following types of adult tissue is (are) comparatively insensitive to effects of ionizing radiation?

Epithelial tissue
Nerve tissue
Muscle tissue

A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3

back 81

C
2 and 3 only

front 82

What is the term used to describe x-ray photon interaction with matter and the transference of part of the photon's energy to matter?
A
Absorption
B
Scattering
C
Attenuation
D
Divergence

back 82

B Scattering

front 83

How do fractionation and protraction affect radiation dose effects?

They reduce the effect of radiation exposure.
They permit cellular repair.
They allow tissue recovery.

A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3

back 83

D
1, 2, and 3

front 84

Which acute radiation syndrome requires the largest exposure before any effects become apparent?
A
Hematopoietic
B
Gastrointestinal
C
Central nervous system (CNS)
D
Skeletal

back 84

C
Central nervous system (CNS)

front 85

Linear energy transfer (LET) may be best described as
A
the amount of energy delivered per distance traveled in tissue.
B
the unit of absorbed dose.
C
radiation equivalent man.
D
radiation absorbed dose.

back 85

A
the amount of energy delivered per distance traveled in tissue.

front 86

If a quantity of radiation is delivered to a body in a short period of time, its effect
A
will be greater than if it were delivered over a long period of time.
B
will be less than if it were delivered over a long period of time.
C
has no relation to how it is delivered in time.
D
is solely dependent on the radiation quality.

back 86

A
will be greater than if it were delivered over a long period of time.

front 87

Which of the following contributes most to patient dose?
A
The photoelectric effect
B
Compton scatter
C
Classical scatter
D
Thompson scatter

back 87

A
The photoelectric effect

front 88

Irradiation of water molecules within the body and their resulting breakdown is termed
A
epilation
B
radiolysis
C
proliferation
D
repopulation

back 88

B
radiolysis

front 89

The symbols 130/56 Ba and 138/56 Ba are examples of which of the following?
A
Isotopes
B
Isobars
C
Isotones
D
Isomers

back 89

A Isotopes

front 90

Which of the dose–response curves shown in Figure 6–2 illustrate(s) illustrates a linear relationship between dose and response?Curve number 1
Curve number 2
Curve number 3

A
1 only

B
2 only

C
1 and 3 only

D
1, 2, and 3

back 90

C 1 and 3 only

front 91

The effect of ionizing radiation on tissue depends on which of the following?

Type of tissue interaction(s)
Amount of interactions
Biologic differences

A
1 and 2 only
B
1 and 3 only
C
2 and 3 only
D
1, 2, and 3

back 91

D
1, 2, and 3

front 92

Isotopes are atoms that have the same
A
mass number but a different atomic number
B
atomic number but a different mass number
C
mass number but a different neutron number
D
atomic number and mass number

back 92

B
atomic number but a different mass number

front 93

The effects of radiation on biologic material depend on several factors. If a quantity of radiation is delivered to a body over a long period of time, the effect
A
will be greater than if it were delivered all at one time
B
will be less than if it were delivered all at one time
C
has no relation to how it is delivered in time
D
depends solely on the radiation quality

back 93

B
will be less than if it were delivered all at one time

front 94

Late or long-term effects of radiation exposure are generally represented by which of the following dose-response curves?
A
Linear threshold
B
Linear nonthreshold
C
Nonlinear threshold
D
Nonlinear nonthreshold

back 94

B
Linear nonthreshold

front 95

Which of the following factors can affect the amount or the nature of radiation damage to biologic tissue?

Radiation quality
Absorbed dose
Size of irradiated area

A
1 only
B
2 only
C
1 and 2 only
D
1, 2, and 3

back 95

D 1, 2, and 3

front 96

What is likely to occur if 25 rad is accidentally delivered to a recently fertilized ovum?
A
Skeletal anomalies
B
CNS anomalies
C
Spontaneous abortion
D
Childhood malignancy

back 96

C
Spontaneous abortion

front 97

Which of the following cell types has the greatest radiosensitivity?
A
Nerve cells
B
Muscle cells
C
Spermatids
D
Lymphocytes

back 97

D
Lymphocytes

front 98

Late effects of radiation, whose incidence is dose related and for which there is no threshold dose, are referred to as
A
nonstochastic
B
stochastic
C
chromosomal aberration
D
hematologic depression

back 98

B
stochastic

front 99

The x-ray interaction with matter that is responsible for the majority of scattered radiation reaching the image receptor (IR) is
A
the photoelectric effect
B
Compton scatter
C
classical scatter
D
Thompson scatter

back 99

B
Compton scatter

front 100

Which of the following ionizing radiations is described as having an RBE of 1.0?
A
10 MeV protons
B
5 MeV alpha particles
C
Diagnostic x-rays
D
Fast neutrons

back 100

C Diagnostic x-rays

front 101

Sources of natural background radiation exposure include
1. the food we eat.
2. air travel.
3. medical and dental x-rays.
A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3

back 101

B 1 and 2 only

front 102

The late effects of radiation are considered to

have no threshold dose.
be directly related to dose.
occur within hours of exposure.

A
1 only
B
1 and 2 only
C
2 and 3 only
D
1, 2, and 3

back 102

B
1 and 2 only