What is aminoglycoside's prototype drug?

gentamycin

How do aminoglycosides work?

they break down bacteria's ribosomes

You would normally take aminoglycosides by themselves. T/F

False. Take aminoglycosides with penicillins or vancomysin for a synergistic effect.

What is aminoglycosides spectrum of activity?

It is effective against gram negative bacteria.

Aminoglycosides have a BBW. What is it for?

ototoxicity and nephrotoxicity (make sure to check labs after peak for creatine levels (renal function). If creatine levels are elevated (renal function is getting worse), hold and notify the provider.)

What is fluroquionoles prototype drug?

ciprofloxacin

What do all fluroquinoles end in?

"-flaxin"

How do fluroquinoles work?

They interfere with the production of bacterial DNA

What would we use ciprofloxacin for?

It is considered the first line drug for Bacillus anthrasis (anthrax).

What are fluroquinoles spectrum of activity?

they are broad spectrum (F)

What route would we give ciprofloxacin in?

orally ONLY

Ciprofloxacin has a BBW. What are they?

tendonitis/tendon rupture, exacerbates weakness in myasthenia gravis.

What would we tell a patient who was just prescribed Ciprofloxacin?

DO NOT take with iron, multivitamins, calcium, dairy products, and AVOID exposure to sunlight. Take 2 hours before or 6 hours after any of these.

A patient currently taking ciprofloxacin is about to have an EKG done. What would be a possible expectation seen on their results?

QT prolongation (longer heartbeat)