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Chapter 17 Adaptive Immunity: Specific Defenses and the Host

front 1

A Treg cell deficiency could result in

  • transplant rejection.
  • increased severity of bacterial infections.
  • increased number of viral infections.
  • increased number of bacterial infections.
  • autoimmunity.

back 1

Autoimmunity

front 2

ADCC is a process that is most effective in destroying

  • bacterial pathogens.
  • bacterial toxins.
  • prions.
  • extracellular viruses.
  • eukaryotic pathogens.

back 2

Eukaryotic pathogens.

front 3

An antibody's Fc region can be bound by

  • macrophages.
  • B cells.
  • T helper cells.
  • antibodies.
  • CTLs.

back 3

Macrophages

front 4

CD4+ T cells are activated by

  • cytokines released by dendritic cells.
  • interaction between CD4+ and MHC II.
  • interaction between TCRs and MHC II.
  • cytokines released by B cells.
  • complement

back 4

Interaction between CD4+ and MHC II

front 5

IL-2, produced by TH cells,

  • causes phagocytosis.
  • activates antigen-presenting cells.
  • stimulates TH cell maturation.
  • activates macrophages.
  • activates TC cells to CTLs.

back 5

Stimulates Th cell maturation

front 6

The antibodies found in mucus, saliva, and tears are

  • IgG.
  • IgM.
  • IgA.
  • IgD.
  • IgE.

back 6

IgA

front 7

The antibodies that can bind to large parasites are

  • IgG.
  • IgM.
  • IgA.
  • IgD.
  • IgE.

back 7

IgE

front 8

The specificity of an antibody is due to

  • the constant portions of the H and L chains.
  • the variable portions of the H and L chains.
  • its valence.
  • the H chains.
  • the L chains.

back 8

the variable portions of the H and L chains

front 9

Thymic selection

  • destroys B cells that make antibodies against self.
  • destroys T cells that do not recognize self-molecules of MHC.
  • destroys MHC molecules.
  • activates B cells.
  • destroys CD4+ cells that attack self.

back 9

destroys T cells that do not recognize self-molecules of MHC

front 10

What type of immunity results from recovery from mumps?

  • innate immunity
  • naturally acquired active immunity
  • naturally acquired passive immunity
  • artificially acquired active immunity
  • artificially acquired passive immunity

back 10

naturally acquired active immunity

front 11

What type of immunity results from vaccination?

  • innate immunity
  • naturally acquired active immunity
  • naturally acquired passive immunity
  • artificially acquired active immunity
  • artificially acquired passive immunity

back 11

artificially acquired active immunity

front 12

When an antibody binds to a toxin, the resulting action is referred to as

  • apoptosis.
  • opsonization.
  • agglutination.
  • neutralization.
  • ADCC.

back 12

neutralization

front 13

Which of the following WBCs are NOT lymphocytes?

  • NK cells
  • B cells
  • helper T cells
  • M cells
  • cytotoxic T cells

back 13

M cells

front 14

Which of the following bacterial components would most likely result in B cell stimulation by T-independent antigens?

  • pili
  • flagellum
  • capsule
  • plasmid
  • ribosome

back 14

capsule

front 15

Which of the following cells is NOT an APC?

  • macrophages
  • dentritic cells
  • natural killer cells
  • mature B cells

back 15

natural killer cells

front 16

Which of the following destroys virus-infected cells?

  • Treg
  • B cells
  • CTL
  • dendritic cells
  • TH
  • None of the answers is correct; all of these are APCs.

back 16

CTL

front 17

Which of the following is the best definition of epitope?

  • specific regions on antigens that interact with antibodies
  • specific regions on antigens that interact with T-cell receptors
  • specific regions on antigens that interact with haptens
  • specific regions on antigens that interact with perforins
  • specific regions on antigens that interact with MHC class molecules

back 17

specific regions on antigens that interact with antibodies

front 18

Which of the following recognizes antigens displayed on host cells with MHC II?

  • basophil
  • B cell
  • TC cell
  • TH cell
  • natural killer cell

back 18

Th Cell

front 19

Which of the following statements is FALSE?

  • The Fc region attaches to a host cell.
  • The constant region of a heavy chain is the same for all antibodies.
  • The variable region of a light chain is partially responsible for binding with antigen.
  • The variable region of a heavy chain is partially responsible for binding with antigen.
  • All of the answers are correct.

back 19

the constant region of a heavy chain is the same for all antibodies

front 20

Which one of the following causes transmembrane channels in target cells?

  • granzymes
  • perforin
  • hapten
  • IL-2
  • IL-1

back 20

perforin