Chapter 17 Adaptive Immunity: Specific Defenses and the Host Flashcards

A Treg cell deficiency could result in

• transplant rejection.
• increased severity of bacterial infections.
• increased number of viral infections.
• increased number of bacterial infections.
• autoimmunity.

ADCC is a process that is most effective in destroying

• bacterial pathogens.
• bacterial toxins.
• prions.
• extracellular viruses.
• eukaryotic pathogens.

An antibody's Fc region can be bound by

• macrophages.
• B cells.
• T helper cells.
• antibodies.
• CTLs.

CD4⁺ T cells are activated by

• cytokines released by dendritic cells.
• interaction between CD4⁺ and MHC II.
• interaction between TCRs and MHC II.
• cytokines released by B cells.
• complement

IL-2, produced by T_H cells,

• causes phagocytosis.
• activates antigen-presenting cells.
• stimulates T_H cell maturation.
• activates macrophages.
• activates T_C cells to CTLs.

The antibodies found in mucus, saliva, and tears are

• IgG.
• IgM.
• IgA.
• IgD.
• IgE.

The antibodies that can bind to large parasites are

• IgG.
• IgM.
• IgA.
• IgD.
• IgE.

The specificity of an antibody is due to

• the constant portions of the H and L chains.
• the variable portions of the H and L chains.
• its valence.
• the H chains.
• the L chains.

Thymic selection

• destroys B cells that make antibodies against self.
• destroys T cells that do not recognize self-molecules of MHC.
• destroys MHC molecules.
• activates B cells.
• destroys CD4⁺ cells that attack self.

What type of immunity results from recovery from mumps?

• innate immunity
• naturally acquired active immunity
• naturally acquired passive immunity
• artificially acquired active immunity
• artificially acquired passive immunity

What type of immunity results from vaccination?

• innate immunity
• naturally acquired active immunity
• naturally acquired passive immunity
• artificially acquired active immunity
• artificially acquired passive immunity

When an antibody binds to a toxin, the resulting action is referred to as

• apoptosis.
• opsonization.
• agglutination.
• neutralization.
• ADCC.

Which of the following WBCs are NOT lymphocytes?

• NK cells
• B cells
• helper T cells
• M cells
• cytotoxic T cells

Which of the following bacterial components would most likely result in B cell stimulation by T-independent antigens?

• pili
• flagellum
• capsule
• plasmid
• ribosome

Which of the following cells is NOT an APC?

• macrophages
• dentritic cells
• natural killer cells
• mature B cells

Which of the following destroys virus-infected cells?

• T_reg
• B cells
• CTL
• dendritic cells
• T_H
• None of the answers is correct; all of these are APCs.

Which of the following is the best definition of epitope?

• specific regions on antigens that interact with antibodies
• specific regions on antigens that interact with T-cell receptors
• specific regions on antigens that interact with haptens
• specific regions on antigens that interact with perforins
• specific regions on antigens that interact with MHC class molecules

Which of the following recognizes antigens displayed on host cells with MHC II?

• basophil
• B cell
• T_C cell
• T_H cell
• natural killer cell

Which of the following statements is FALSE?

• The Fc region attaches to a host cell.
• The constant region of a heavy chain is the same for all antibodies.
• The variable region of a light chain is partially responsible for binding with antigen.
• The variable region of a heavy chain is partially responsible for binding with antigen.
• All of the answers are correct.

Which one of the following causes transmembrane channels in target cells?

• granzymes
• perforin
• hapten
• IL-2
• IL-1