front 1 Tears and mucus membranes would be a part of which defense system? innate external defenses innate internal defenses adaptive defenses | back 1 innate external defenses |
front 2 Phagocytotic cells such as macrophages identify a variety of enemies by recognizing markers unique to pathogens. They would be classified as which type of defense system? innate internal defenses adaptive defenses innate external defenses | back 2 innate internal defenses |
front 3 What cells make antibodies? plasma B cells cytotoxic T cells memory B cells memory T cells | back 3 plasma B cells |
front 4 What is the name of the unique area (specific region) that a lymphocyte recognizes and binds to? antigen pathogen antibody an antigenic determinant | back 4 an antigenic determinant |
front 5 What type of immunity can be transferred by bodily fluids from one
person to another, thus conferring immunity to the recipient?
cell-mediated immunity cellular immunity | back 5 humoral immunity |
front 6 If a virus attacks a cell, which type of immunity would be activated? antibody-mediated immunity humoral immunity cell-mediated immunity (cellular immunity) | back 6 cell-mediated immunity (cellular immunity) |
front 7 Cancer cells would be attacked by which of the following cells? B cells macrophages Cytotoxic T cells | back 7 Cytotoxic T cells |
front 8 What is the role of helper T cells in the adaptive immune response? Helper T cells activate B cells and cytotoxic T lymphocytes to kill infected host cells. Helper T cells directly kill infected host cells. Helper T cells phagocytize bacteria and viruses. Helper T cells produce and secrete antibodies. | back 8 Helper T cells activate B cells and cytotoxic T lymphocytes to kill infected host cells. |
front 9 What is meant by the clonal expansion of a B cell? An activated B cell will engulf and digest anything foreign. An activated B cell divides into cells that give rise to memory B cells and plasma cells. An activated B cell will immediately begin to produce antibodies. An activated B cell will kill infected host cells. | back 9 An activated B cell divides into cells that give rise to memory B cells and plasma cells. |
front 10 The student who caught the cold caused by this specific Rhinovirus was exposed to the exact same Rhinovirus 18 months later. What component of the immune system will protect her from getting the same cold again? Memory B cells Dendritic cells Plasma cells Antibodies that are “left over” from the last infection | back 10 Memory B cells |
front 11 Correctly order the steps involved cellular immunity:
2,1,3,4 2,4,1,3 1,2,4,3 4,2,1,3 | back 11 2,4,1,3 |
front 12 Which of the following is NOT a step used by cytotoxic T cells to kill infected host cells? Secretion of perforin Recognition of infected host cell using its CD4 glycoprotein Recognition of infected host cell using its TCR Secretion of granzyme | back 12 Recognition of infected host cell using its CD4 glycoprotein |
front 13 Place the following steps of phagocytosis in the order that they occur:
2,1,3,4,5 1,2,4,3,5 2,1,4,3,5 2,4,1,3,5 | back 13 2,1,4,3,5 |
front 14 Which pair of molecules do NOT directly interact with one another? BCR and epitope BCR and TCR CD8 and MHC-I CD4 and MHC-II | back 14 BCR and TCR |
front 15 Which of the following is NOT a step that ultimately leads to antibody production? Activation of cytotoxic T cells by helper T cells Immature B cells conducting surveillance for foreign epitopes Differentiation of plasma cells Activation of helper T cells by dendritic cells | back 15 Activation of cytotoxic T cells by helper T cells |
front 16 A person who has AIDS contracts rare and often life-threatening infections because their helper T cell count is so low. Which of the following components of the immune response still respond to antigen despite the low helper T cell count? Clonal selection of B cells Apoptosis of infected host cells Clonal expansion and antibody production Activation of cytotoxic T cells | back 16 Clonal selection of B cells |
front 17 Which of the following statements is true? Adaptive defenses include humoral immunity only. Adaptive defenses include both humoral and cellular immunity. Memory B cells are typically established when the B cell binds to an antigen. Innate defenses are enough to keep a person healthly. | back 17 Adaptive defenses include both humoral and cellular immunity. |
front 18 Which of the following are antigen-presenting cells (APC)? T cells natural killer cells memory cells B cells | back 18 B cells |
front 19 Which of the following cells engulf antigens and present fragments of them on their own surfaces for recognition? T lymphocytes NK cells dendritic cells plasma cells | back 19 dendritic cells |
front 20 Which cells secrete histamines that trigger inflammatory pathways? mast cells macrophages neutrophils NK cells | back 20 mast cells |
front 21 Which of the following is an effect of complement activation? opsonization tissue repair fever T cell activation | back 21 opsonization |
front 22 Class II MHC proteins are found on which of the following cell types? all nucleated cells antigen-presenting cells | back 22 antigen-presenting cells |
front 23 Which class of MHC proteins presents exogenous antigens? class I MHC proteins class II MHC proteins | back 23 class II MHC proteins |
front 24 Class I MHC proteins are recognized by which of the following cell types (that are destined to become T cells)? CD8 CD4 | back 24 CD8 |
front 25 Which of the following types of cells display protein fragments produced by the cancer within them? all nucleated cells macrophages B cells dendritic cells | back 25 all nucleated cells |
front 26 Which major class of lymphocytes become cytotoxic T cells? CD4 cells CD6 cells CD8 cells | back 26 CD8 cells |
front 27 Which of the following activate CD8 cells? peptides containing 14-17 amino acids antigen fragments on class I MHC proteins exogenous antigens antigens on class II MHC proteins | back 27 antigen fragments on class I MHC proteins |
front 28 What type of T cell can directly attack and kill other cells, such as virus-infected cells? cytotoxic T (TC) cells APC regulatory T (TReg) cells helper T (TH) cells | back 28 cytotoxic T (TC) cells |
front 29 Which of these mechanisms do cytotoxic T (TC) cells use to destroy a target--that is, deliver a lethal hit? the seeking of cells lacking class I MHC proteins agglutination of target cells perforation of the membrane opsonization | back 29 perforation of the membrane |
front 30 Which type of T cell will recognize antigens associated with an organ transplant? helper T (TH) cells cytotoxic T (TC) cells CD8 cells regulatory T (TReg) cell | back 30 cytotoxic T (TC) cells |
front 31 T cells achieve self-tolerance in the __________. bone marrow thymus tonsils lymph nodes | back 31 thymus |
front 32 Which of the following are NOT appropriately matched? helper T cells: destroy infected cells B cells: produce free antibodies cytotoxic T cells: destroy virally infected cells macrophages: antigen-presenting cells | back 32 helper T cells: destroy infected cells |
front 33 Activated CD8 cells become __________. B cells cytotoxic T cells NK cells helper T cells | back 33 cytotoxic T cells |