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Chapter 21 Lympatic/Immune System

front 1

Organisms that cause disease, such as bacteria or fungi, are considered

back 1

pathogens

front 2

Redness, heat, swelling, and pain are signs/symptoms that accompany

back 2

inflammation

front 3

List the features of the skin that offer immunoprotection

back 3

presence of lactic acid

continuous barrier to the external environment

presence of defensins

front 4

The lymphatic system's functions are

back 4

immunity, absorption of lipids, and fluid recovery

front 5

A mast cell is very similar to the type of leukocyte called a _____. Both secrete histamine, heparin, and other chemicals involved in inflammation

back 5

basophil

front 6

List three examples of antimicrobial proteins

back 6

defensins, interferon, complement

front 7

List the correct order of lymphatic flow through a lymph node

back 7

afferent lymphatic vessel

subcapsular sinus of the cortex

sinuses of the cortex and medulla

efferent lymphatic vessel

front 8

Cells derived from blood monocytes that function as phagocytes and antigen-presenting cells are called

back 8

macrophages

front 9

The type of defense that guards against a broad range of pathogens is ____ resistance

back 9

nonspecific

front 10

Abnormal accumulation of non-inflammatory tissue fluid resulting in swelling of the tissue is known as

back 10

edema

front 11

Lymphatic cells called NK (natural killer) cells are classified as

back 11

lymphocytes

front 12

List three secondary lymphoid organs

back 12

spleen, lymph node, tonsils

front 13

List the functions of a lymph node

back 13

site of B and T cell activation

filtration of lymph

front 14

Eosinophils secrete

back 14

superoxide

front 15

Hematopoiesis occurs in the ____ bone marrow

back 15

red

front 16

Name the cells that release inflammatory mediators such as histamine, leukotrienes, and hepain

back 16

mast cells, basophils

front 17

Follow the flow of lymphatic fluid in the correct order beginning with the blood capillaries

back 17

blood capillaries

interstitial spaces

lymphatic capillaries

lymphatic vessels

lymphatic ducts

internal jugular and subclavian vein junction

front 18

Identify the body's largest lymphatic organ(s), located in the left hypochondriac region

back 18

spleen

front 19

A ____ is the type of granulocyte with multi-lobed nucleus that serves especially to destroy bacteria by means of phagocytosis, intracellular digestion, and secretion of bactericidal chemicals

back 19

neutrophil

front 20

Name the cell that is found in the epidermis, mucous membranes, and lymphoid tissues that initiates immune responses by activating lymphocytes and secreting cytokines

back 20

dendritic cell

front 21

Name the granulocyte that functions to destroy bacteria by means of phagocytosis, intracellular digestion, and secretion of bactericidal chemicals

back 21

neutrophil

front 22

Name the plasma proteins that make powerful contributions to both nonspecific resistance and specific immunity

back 22

complement

front 23

List the features of the tonsils

back 23

lymphatic nodules

an incomplete fibrous capsule

tonsillar crypts

front 24

List some cells that are classified as lymphocytes

back 24

B cells

T cells

NK cells

front 25

Name the cells that produces and secretes antibodies

back 25

plasma cells

front 26

Distinct connective tissue capsules are found surrounding the lymphatic

back 26

organs

front 27

The thymus is considered part of several body systems. Name these

back 27

endocrine, immune, and lymphatic systems

front 28

Humoral immunity is mediated by antibodies secreted by _____ cells

back 28

B

front 29

Name the leukocyte that functions as an antibody-producing cell

back 29

plasma cell

front 30

A cell that phagocytizes an antigen and displays fragments of it on its surface for recognition by other cells of the immune system is a ____ _____ cell

back 30

antigen presenting

front 31

_____ T cells perform a central coordinating role in both humoral and cellular immunity

back 31

helper

front 32

Name the term for an abnormal elevation in body temperature

back 32

fever

front 33

Name the body system that functions to maintain fluid balance in the tissue, absorbs lipids, and protects against pathogens

back 33

lymphatic system

front 34

List the events of B cell recognition and attack in the correct order

back 34

Immunocompetent B cells bind to antigen

B cell internalizes/displays antigen on MHC-II to TH cell

TH cells secrete interleukins which activate the B cell

B cell undergoes clonal selection

Differentiation of B cells into plasma cells and memory cells

Plasma cells produce and secrete antibodes

front 35

List the tissue which lack lymphatic vessels

back 35

bone marrow, cornea, central nervous system, and cartilage

front 36

Describe lymphatic capillaries

back 36

close-ended vessels consisting of loosely overlapping endothelial cells

front 37

The ____ line of defense consists of several nonspecific defense mechanisms against pathogens that break through the skin or mucous membranes

back 37

second

front 38

Name three inflammatory mediators released by basophils and mast cells

back 38

heparin, histamine, and leukotriene

front 39

____ T cells attack and destroy infected body cells, cancerous cells, and the cells of transplanted tissues by secreting perforins and granzymes

back 39

cytotoxic

front 40

Name the component of the lymphatic system that consists of unencapsulated aggregates of lymphocytes in the connective tissues and mucous membranes of various organs

back 40

lymphatic tissues

front 41

The accumulation of dead cells, fluid, and tissue debris is called

back 41

pus

front 42

Name the organ where T-cells mature

back 42

thymus

front 43

Name the cells that produce the stroma of lymphatic organs

back 43

reticular cells

front 44

The specialized lymphatic capillaries located in the villi of the small intestines are the

back 44

lacteals

front 45

Name some beneficial effects of fever

back 45

inhibition of bacterial and viral replication

elevated metabolic rate

elevated interferon activity

front 46

Name the leukocyte that transforms into a macrophage when it moves from the blood into the tissues

back 46

monocyte

front 47

The third line of defense against pathogens is

back 47

the immune system's specific defenses

front 48

List the mechanisms used by eosinophils to kill parasites

back 48

producing hydrogen peroxide

producing superoxide anion

front 49

The fluid contained in lymphatic vessels, which originates as tissue fluid, is called

back 49

lymph

front 50

The first line of defense against pathogens consist of

back 50

external barriers

front 51

List the features of lymphatic vessels

back 51

smooth muscle in vessel wall

valves present

tunica interna present

front 52

_____ T cells are descended from the cytotoxic T cells and are responsible for memory in cellular immunity

back 52

memory