front 1 Which of the following is the correct drug class for emtricitabine? | back 1 Nucleoside Reverse Transcriptase Inhibitor (NRTI) |
front 2 ML comes to the emergency department with a severe skin rash and epidermal detachment. He is diagnosed with toxic epidermal necrolysis (TEN). He states he was recently started on some HIV medications. Which of the following medications is most likely the cause of his TEN reaction? | back 2 Nevirapine All NNRTIs can cause severe, life-threatening skin reactions including SJS/TEN. |
front 3 History of Present Illness: SM is a 36-year-old male who presents to the HIV clinic for a routine appointment. He is doing well and has no major complaints at this time. He states that he uses his albuterol inhaler 4 days per week (about 6 puffs on each of those days) and has been trying over-the-counter medications to manage occasional heartburn. Allergies: sulfa (hives) Medications: Truvada 1 tablet PO dailyTivicay 50 mg PO dailyAlbuterol MDI 1-2 inhalations 3-4 times daily, as neededAfrin 2-3 sprays in each nostril twice daily, as neededSimvastatin 20 mg PO QHS When treating his heartburn, which OTC medication has the greatest risk for a drug interaction with SM's current medications? | back 3 Maalox |
front 4 **case above** Medications: Truvada 1 tablet PO dailyTivicay 50 mg PO dailyAlbuterol MDI 1-2 inhalations 3-4 times daily, as neededAfrin 2-3 sprays in each nostril twice daily, as neededSimvastatin 20 mg PO QHS Which mechanisms of action are represented by SM's HIV therapy? | back 4 INSTI and two NRTI |
front 5 Which medication has a boxed warning for the risk of serious hypersensitivity reactions? | back 5 Abacavir |
front 6
History of Present Illness: QL is a 25-year-old white
female who presents to the family medicine clinic. She complains that
she is extremely depressed and is having trouble sleeping. It is
impacting her ability to take care of her 3-year-old daughter. Which of the following could be contributing to QL's complaint? | back 6 A side effect from the rilpivirine component of Complera |
front 7 **case above** Which of the following is an appropriate recommendation for the treatment of QL's acid reflux? | back 7 Tums QL is taking Complera, which is a combination tablet containing rilpivirine. Rilpivirine requires an acidic gut for absorption and should be avoided with proton pump inhibitors. Carafate and Reglan are not recommended for the treatment of GERD |
front 8 What is the integrase strand transfer inhibitor (INSTI) component of Triumeq? | back 8 Dolutegravir |
front 9 Which combination of medications is a recommended initial regimen for HIV that can be administered as a single pill? | back 9 Dolutegravir + abacavir + lamivudine |
front 10 Which antiretroviral drug is available as an intravenous formulation that is used to prevent perinatal transmission of HIV? | back 10 Zidovudine |
front 11 WF is a 54-year-old male who comes to the clinic due to new-onset muscle pain that has been persistent for the past week. Past Medical History: hypertension, type 2 diabetes mellitus, HIV, opioid use disorder Social History: prior IV drug use (heroin), has not used in 2 years Allergies: NKDA
Medications:
Creatinine phosphokinase 784 IU/L Which medication is most likely responsible for the patient's symptoms and laboratory findings? | back 11 Isentress |
front 12 A healthcare worker has started post-exposure prophylaxis therapy for a needlestick injury. How long should the treatment be continued? | back 12 4 weeks |
front 13 Which of the following is an appropriate generic substitution for Prezista? | back 13 Darunavir |
front 14 A patient gave the pharmacist a prescription for Isentress. Which of the following should be dispensed? | back 14 Raltegravir |
front 15 Which antiretroviral class should be administered separately from antacids? | back 15 INSTI The absorption of INSTIs is decreased when given with polyvalent cations. INSTIs should be taken 2 hours before or 6 hours after cation-containing products, including antacids. |
front 16 An HIV-positive patient currently taking Complera comes to the pharmacy counter with a box of Prilosec OTC. How should the pharmacist counsel the patient? | back 16 Do not take Prilosec OTC with Complera |
front 17 TK is a 46-year-old male who comes to the HIV clinic for a regularly scheduled follow-up visit on July 9th. Laboratory work was completed prior to the visit. He has no specific complaints and states that he feels well. Past Medical History: HIV (diagnosed 8 years ago), hypertension, prediabetes, dyslipidemia Allergies: NKDA 5/8: Dovato 1 tablet daily (3 refills) Which of the following drug classes are represented by the antiretroviral medication prescribed on May 8th? (Select ALL that apply) | back 17 INSTI and NRTI |
front 18 LA is a 31-year-old female who started antiretroviral therapy 2
months ago when she was found to be HIV-positive (viral HIV RNA load =
140,000 copies/mL, CD4+ count = 47 cells/mm3). She now
presents with signs and symptoms of immune reconstitution inflammatory
syndrome (IRIS). What is an appropriate course of
action? | back 18 Continue her current antiretroviral therapy |
front 19 Which combination antiretroviral drug contains tenofovir alafenamide? | back 19 Biktarvy |
front 20 OP has HIV and has been stable on S tribild for 16 months. Stribild contains a pharmacokinetic booster to increase the levels of which component? | back 20 Elvitegravir |
front 21 KD is a 35-year-old female with no known past medical history. She is married to an HIV-positive man. She has received a prescription for pre-exposure prophylaxis. Which labs must be performed before beginning therapy? (Select ALL that apply.) | back 21 HIV test Hepatitis B test |
front 22 Referring to the figure, which choice best represents the site where lamivudine exerts its mechanism of action? **image** | back 22 Choice C |
front 23 A pharmacist receives a prescription for emtricitabine + tenofovir disoproxil fumarate. What drug can be dispensed to provide this combination in a single tablet? | back 23 Truvada |
front 24 HM is a 35-year-old pregnant female with newly diagnosed HIV. She is being started on a regimen that contains lamivudine + abacavir. What drug can be dispensed to provide this combination in a single tablet? | back 24 Epizicom |
front 25 Stribild is contraindicated in which of the following conditions? | back 25 CrCl < 50 mL/min. |
front 26 MK is a 31-year-old male who presents to the HIV clinic today for a
routine appointment. He is doing well and has no complaints at this time. Which medications are contained in MK's antiretroviral regimen? (Select ALL that apply.) | back 26 Emtricitabine, elvitegravir, cobicistat, tenofovir disoproxil fumarate |
front 27 Which of the following is a risk associated with didanosine? | back 27 Pancreatitis |
front 28 A 32-year-old female is picking up a new prescription for Truvada for HIV preexposure prophylaxis. During counseling, she asks the pharmacist how HIV is most likely to be transmitted. Which of the following exposures are high risk for transmission of the virus? (Select ALL that apply) | back 28 Condomless sexual contact involving the exchange of semenInjecting drugs with a needle used by someone else |
front 29 Referring to the figure, which choice best represents the site where Tivicay exerts its mechanism of action? | back 29 Choice D |
front 30 Which of the following is considered a first-line treatment regimen for a patient with newly diagnosed HIV? | back 30 Dovato |
front 31 Atripla contains the following medications: | back 31 Tenofovir disoproxil fumarate, emtricitabine, efavirenz |
front 32 A 28-year-old male was informed that a new partner tested positive for HIV. He last had sexual contact with the partner 1 month ago. What is the earliest point that the OraQuick In-Home HIV Test can be performed to reliably identify that this patient is not infected with HIV? | back 32 In 2 months |
front 33 PS is a 65-year-old male who has been HIV positive for 20 years. He reports that for the past six months he has not had an appetite and has lost significant muscle mass. Which of the following drugs could be recommended to address PS's concerns? (Select ALL that apply.) | back 33 Megace ES Dronabinol Nabilone |
front 34 JR is a 45-year-old male who was recently diagnosed with HIV. He
brings his current medication list to the clinic during a routine
check-up. The pharmacist should contact the medical provider about which of the following interaction/s? (Select ALL that apply.) | back 34 Simvastatin and ritonavir Prezista and simvastatin |
front 35 Which of the following HIV medications should be taken with food? (Select ALL that apply.) | back 35 Rilpivirine, complera, genvoya |
front 36 A phlebotomist had an accidental needlestick injury while drawing a blood sample from an HIV-positive patient. Which drug combination is the preferred regimen for post-exposure prophylaxis? | back 36 Raltegravir + tenoforvir disproxil fumarate + emtricitabine |
front 37 KD is a 35-year-old female who is HIV-negative and is married to an HIV-positive man. She is interested in treatment to decrease her chances of contracting HIV. Which of the following would be an appropriate recommendation? | back 37 Emtricitabine + tenofovir disoproxil fumarate |
front 38 Which of the following is a warning for all drugs classified as Nucleoside Reverse Transcriptase Inhibitors (NRTIs)? | back 38 Lactic acidosis |
front 39 Cobicistat is used in some antiretroviral treatment regimens as a/an | back 39 CYP450 3A4 inhibitor |
front 40 While drawing blood for routine laboratory tests, a phlebotomist accidentally sticks herself with a needle that she has withdrawn from the arm of an HIV-positive patient. What is the appropriate treatment for the phlebotomist? | back 40 A 4-week course of Truvada and Isentress |