The Pulmonary Circuit
Carries blood to and from gas exchange surfaces of lungs
The Systemic Circuit
- Carries blood to and from the body
- Blood alternates between pulmonary circuit and systemic circuit
Three Types of Blood Vessels
- Arteries
- Veins
- Capillaries
Arteries
Carry blood away from heart
Veins
Carry blood to heart
Capillaries
- Networks between arteries and veins
- Exchange materials between blood and tissues
- Materials include dissolved gasses, nutrients, waste products
Four chambers of the heart
- Right atrium
- Right Ventricle
- Left Atrium
- Left Ventricle
Right Atrium
Collects blood from the systemic circuit
Right Ventricle
Pumps blood to pulmonary circuit
Left Atrium
Collects blood from pulmonary circuit
Left Ventricle
Pumps blood to systemic circuit
Coronary Sulcus
- Divides atria and ventricles
- Part of the external anatomy of the heart
Anterior Interventricular Sulcus and Posterior Interentricular Sulcus
- Seperates left and right ventricles
- Part of external anatomy of the heart
- Contain blood vessels of cardiac muscle
External Characteristics of the Atria
- Thin walled
- Expandable outer auricle (atrial appendage)
- Each has pectinate muscles (ridges) anteriorly
- left and right separated by interatrial septum
External Characteristics of Ventricles
- inferior, thick walls, lined with trabeculae carneae (muscle ridges)
- left and right separated by interventricular septum
- Left ventricle 3x thicker than right
- Left has same volume as right
- Left is round, right is crescent
Trabeculae Carneae
Line the ventricles and make the contraction of the heart as a whole.
Interatrial septum
Separates atria
Interventricular Septum
Seperates ventricles
Atrioventricular Valves
Between the atria and ventricles
Tricuspid Valve
- Atrioventricular valve on between the right atria and the right ventricle
- Has 3 cusps (flaps)
Bicuspid Valve
- Atrioventricular valve between the left atria and left ventricle
- Has 2 cusps (flaps)
Cusp Attachment
Attached to chordae tendineae from papillary muscles on ventricle wall
What prevents cusps from opening backward during ventricle contraction?
The contraction of papillary muscles
When ventricles are not contracting what happens to the cusps?
Cusps hang loose, allowing the ventricles to fill with blood
Semilunar Valves
- Between ventricles and arteries
- 3 cusps, no chordae tendineae or muscles
- forced open by blood from ventricular contraction
- snap closed to prevent backflow
What makes up the Heart Wall?
- Epicardium
- Myocardium
- Endocardium
Epicardium
- Outer Layer
- Covers the heart
- Visceral pericardium
Myocardium
- Middle Layer
- Muscular wall of the heart
- Concentric layers of cardiac muscle tissue
- Atrial myocardium wraps around great vessels
- Two divisions of ventricular myocardium
Endocardium
- Inner Layer
- Simple squamous epithelium
Valvular Heart Disease (VHD)
Valve function deteriorates to extent that heart cannot maintain adequate circulation
Heart Murmur
leaky valve
Mitral Valve Prolapse
- Murmur of the left AV valve
- Cusps don't close properly
- Blood regurgitates back into left atrium
Congestive Heart Failure
- Decreased pumping efficiency due to diseased valves or damaged muscle
- Blood backs up
- fluid leaks from vessels and collects in lungs and tissues
Cardiomyocytes
Heart muscle cells
Cardiac Muscle Tissue
- Uses actin and myosin sliding filaments to contract
- rich in mitochondria, resists fatigue but dependent on aerobic respiration
- cells connected by intercalated discs
Intercalated discs
- connect cells in Cardiac Muscle Tisse
- consists of desmosomes and gap juntions
- convey force of contraction
- propagate action potentials
Foramen Ovale
- Found in the fetal heart
- 25% of blood bypasses the lungs directly to the left atrium
- Closes at birth
Fossa Ovalis
Scar left after the foramen ovale closes at birth
Ductus arteriosus
- Found in fetal heart
- connects pulmonary trunk to aorta
- 90% of blood bypasses lungs
- Closes at birth
Ligamentum Arteriosum
Scar left after the Ductus arteriosus closes after virth
Blue Baby Syndrome
Failure of either the foramen ovale or the ductus arteriosus to close after birth. Causing poor oxygenation of blood.
Coronary Circulation
- Blood supply to the heart
- Supplies blood to muscle tissue of heart via coronary arteries or coronary veins
Coronary Arteries
- Originate at base of ascending aorta
- Branch to capillary beds for diffusion
Coronary Veins
Blood returns via cardiac veins that join to form coronary sinus whic empty into right atrium
Heart Beat
Single contraction of the heart
Automaticity
Cardiac muscle tissue contracts automatically
Two types of cardiac muscle cells
- Conducting system
- Contractile Cells
Conducting System
- Controls and coordinates heartbeat
- SA node
- AV node
- Conducting cells
Conducting Cells
- AV bundle
- Bundle Branches
- Purkinje fibers
Purkinje Fibers
Connect nodes and myocardium, run down interventricular septum and around apex
Contractile Cells
Produce contractions that propel blood
SA node location
Right atrium wall near superior vena cava
AV node location
Inferior portion of interatrial septum above tricuspid valvle
Conduction through the heart
- SA node activity and atrial activation begin
- Stimulus spreads across the atrial surfaces and reaches the AV node
- There is a 100 msec delay at AV node then atrial contraction begins 150 msec
- The impulse travels along the interventricular septum within the AV bundle and the bundle branches to the Purkinje fibers, and via the moderator band, to the papilary muscles of the right ventricle. 176 msec
- The impulse is distributed by the Purkinje fibers and relayed throughout the ventricular myocardium. Atrial contraction is completed. Ventricular contraction begins 225 msec
P Wave
Atrial depolarization (contract)
QRS Wave
Ventricular depolarization (contract)
T Wave
Ventricular repolarization (relax)
The Cardiac Cycle
- The period between the start of one heartbeat and the beginning of the next
- Includes both contraction and relaxation
Two Phases of the Cardiac Cycle
- Systole
- Diastole
Phase of Cardiac Cycle
- Atrial systole
- Atrial diastole
- Ventricular systole
- Ventricular diastole
Ventricular Ejection
Ventricular pressure exceeds vessel pressure opening the semilunar valves and allows blood to leave the ventricle.
Stroke Volume
The amount of blood ejected is during ventricular ejection
SV= SYSTOLIC - DIASTOLIC
Cardiac Output
The volume pumped by left or right ventricle in one minute
CO= HR X SV