_____ excretion represents the major route of water loss
urine
A buffer is any mechanism that resists changes in pH by
converting a strong acid or base to a weak one
List the roles of calcium
participate in muscle contraction
participates in bone and tooth development
acts as a second messenger and activates exocytosis during neurotransmission
acts as a factor for blood clotting
Water output is significantly controlled through variations in
urine volume
A person is in a state of fluid ____ when daily gains and losses are equal.
balance
Rank the following routes of normal water loss from largest volume to smallest volume
urine
cutaneous transpiration
breath
feces
sweat
The combination of water from food and drink is known as _____ water
preformed
Prolonged, heavy work ____ the respiratory loss to 650 mL/day and perspiration to 5 L/day; at the same time it ____ urine output by nearly two-thirds
raises; reduces
Indicate which of the following statements is correct regarding the abundance of electrolytes in the ECF and ICF
sodium is more abundant in the ECF and potassium is more abundant in the ICF
The two main categories of acid-base imbalances are respiratory and
metabolic
Cellular function requires a fluid medium with a carefully controlled composition. Select the three mechanisms by which the body maintains homeostatic balance
electrolyte, water, and acid-base balance
Indicate which of the following are examples of fluid sequestration
pleural effusion
hemorrhage
edema
Name the most abundant cation of the intracellular fluid, which is the greatest determinant of intracellular osmolarity and cell volume
potassium
____ is the principal cation of the ECF; it accounts for 90% to 95% of the osmolarity of the ECF and therefore it is the most significant solute in determining total body water
sodium
The ____ of a solution is determined by its hydrogen ions
pH
The most important buffer system in the blood is the bicarbonate buffer, which is a solution of ____ acid and bicaronate ions
carbonic
Indicate which of the following regulate sodium homeostasis
aldosterone
antidiuretic hormone
natriuertic peptides
Indicate which of the following are the functions of chloride ions
important in osmotic balance
participate in chloride shift that accompanies CO2 loading and unloading
contribute to formation of stomach acid
play major role in the regulation of body pH
Indicate which of the following statements are true regarding fluid sequestration
causes of fluid sequestration include edema and hemorrhage
it is a condition in which excess fluid accumulates in a particular location
The plasma concentration of chloride less than 95 mEq/L is called ______ and it is usually a side effect of hyponatremia
hypochloremia
Name the condition in which plasma sodium concentration is less than 130 mEq/L
hyponatremia
A ____ buffer is a system - namely, the respiratory or urinary system - that stabilizes pH by controlling the body's output of acids, bases, or CO2
physiological
____ play a crucial role in governing the body's water distribution and total water content
electrolytes
A deficiency of CO2 is called
hypocapnia
Indicate which of the following are examples of preformed water
water in a baked potato and steak dinner
water in an apple
water in a glass of milk
List the components of transcellular fluid
vitreous and aqueous humors of the eye
bile; and fluid in the digestive, urinary, and respiratory tracts
cerebrospinal, synovial, peritoneal, pleural, and pericardial fluids
Indicate four factors that can lead to volume depletion (hypovolemia), in which proportionate amounts of water and sodium are lost
chronic vomiting
hemorrhage
profuse sweating
diarrhea
A blood pH below 7.35 is defined as a state of _____
acidosis
The _____ can neutralize more acid or base than either the respiratory system or the chemical buffers
kidneys
Prolonged exposure to _____ can dehydrate a person
heat or cold
Indicate which of the following is not an anion electrolyte
calcium ion
Imbalances of water can also cause
electrolyte and acid-base imbalances
Most magnesium is found in intracellular fluid complexed with
ATP
Indicate which of the following are the two types of increase of fluid in the body
volume excess
hypotonic hydration
ADH release is inhibited when
blood osmolarity is too low
blood volume and pressure is too high
Plasma concentrations of calcium less than 4.5 mEq/L are known as
hypocalcemia
True imbalances in ____ concentration are relatively rare because its excess or depletion is almost always accompanied by proportionate changes in water volume
sodium
Indicate which of the following are fast-acting stimuli that cause a short-term inhibition of thirst
cooling or moistening the mouth
Identify the "salt-retaining hormone"
Aldosterone
List the tree major chemical buffer systems of the body
bicarbonate
phosphate
protein
The condition called _____ is a dangerously high plasma potassium concentration greater than 5.5 mEq/L
hyperkalemia
Every process that depends on ATP depends on ____ ions
phosphate
Calcium concentration is regulated chiefly by ______ hormone and calcitriol, and in children by calcitonin
parathyroid
In _____ transpiration, water diffuses through the epidermis and evaporates
cutaneous
The primary effects of aldosterone are that the urine contains ____ NaCl and ____ potassium and has a ____ pH
less; more; lower