Pathogen
any organism capable of causing disease in its host
Jenner
first inoculation
Semmelweiss
linked handwashing to disease
Hook
named cells
Koch
anthrax
Ehrlich
father of chemotherapy
Pasteur
pasterization
Pasteur
rabies incoluation
Lister
used carbon acid in surgery
What are the four organic compounds
Alcohol, aldehyde, ketone, organic acid
enzymes
protein catalyst that controls the rate of chemical reactions in cells
denaturization
disruption of hydrogen bonds an other weak forces that maintain the structure of a globular protein
wet mount
technique in which a drop of fluid containing microorganisms is place on a slide
smear
thin layer of liquid specimen spread out on a microscopic slide
stain
molecule that can bind a structure and give it color
Why is a gram stain important?
Determines type of antibiotic may be effective due to cell wall construction
coccus
spherical
bacillus
rod-shaped
spirillum
wavy or spiral
staphylo
clusters
strepto
chains
diplo
pairs
tetra
four cells in a cube
sarchina
eight cells in a cube
Gram positive
lot of peptidoglycan and is sensitive to antibiotics
Gram negative
thin layer of peptidoglycan and less sensitive to antibiotics
endospore
resistant, dormant structure that can survive adverse conditions
endotoxin
toxin incorporated in gram-negative bacteria cell walls and released when bacteria dies
L forms
irregularly shaped naturally occurring bacteria with defective cell walls
denaturization of enzymes
loses normal shape; cannot form enzyme-substrate complex
Lag phase
adapt to new environments and getting ready to divide
log phase
period of greatest cell division: exhibits most typical size and shape
stationary phase
population remains the same: some cells form while the same amount dies
decline phase
more and more cells die
Physical growth
pH, temperature, oxygen concentration, moisture, hydrostatic pressure, osmotic pressure, and radiation
Nutritional
carbon, nitrogen, sulfur, phospherus, trace elements, and vitamins
streak plate
bacteria are lightly spread over the same surface of agar plates, results in isolated colonies
defined synthetic medium
contains known specific kinds and amount of chemical substances
complex medium
reasonably familiar materials but varies slightly in chemical composition from batch to batch
natural media
bacteria and other things growing together in oceans, lakes, and soil & living and dead organisms
selective media
encourages growth of some organisms but suppresses growth of other organisms
differential medium
observable changes (color, pH)
mutagen
agent that increases rate of mutations
transformation
change in an organisms characteristics because of transfer of genetic information
transduction
transferring genetic material by DNA being carried by bacteria-phages
conjugation
genetic material change but the donor and recipient must have contact & transfers much larger quantities of DNA
nucleic acid
DNA
capsid
protein subunit that surround nucleic acid
enveloped viruses
bilayer membrane outside their capsid
naked virus
no bilayer membrane outside of capsid
spikes
projections extending from viral envelope
viral specificity
specific kinds of cell a virus can infect whether a virus can or cannot attach to a cell
prion
exceedingly small infectious particle consisting of protein without any nucleic acid
parasite
an organism that lives at the expense of another organism
host
thing that a parasite attaches to
definitive host
harbor parasite while it reproduces sexually
reservoir hosts
infected organism that make parasites available for transmission to other hosts
helmiths
worms
scolex
head end of tapeworm
progliottid
body components mainly of reproductive organs of both sexes
hyphae
a long, threadlike structure of cells in fungi
Platyhelminthes
flatworms that live in or on hosts
nematodes
roundworms that live in the intestine or circulatory system of hosts
What percent of alcohol is most effective
70%
what all affect the effectiveness of antimicrobial agents
time, temperature, pH, & concentration
Agents kill by what means
chemical and physical
antibiotic
chemical substance produced by microorganisms which has the capacity to inhibit the growth of bacteria
superinfection
invasion by replacement microflora
zone of inhibition
clear area that appears on agar in the disk diffusion method
pathogen
parasite capable of causing disease in a host
contamination
presence of microorganisms on inanimate objects or surfaces of skin and mucous membranes
infection
multiplication of a parasitic organism, usually microscopic, within or upon the host's body
virulence
degree of intensity of the disease produced by a pathogen
sign
disease characteristic that can be observed by examining the patient
symptom
disease characteristic that can be observed or felt only by the patient, pain or nausea
sequelae
aftereffect of a disease
endemic
disease that is constantly present in a specific population
epidemic
disease that has a higher than normal incidence in a population over a relatively short period of time
pandemic
epidemic that has become world wide
virulence factors
characteristics that improve the chance of successful host invasion and infection
CDC
Center of Disease Control
nosocomial infections
infection acquired in a hospital or other medical facility
top nosocomial infections
Staphlococcus aureus, E. coli, streptococcus
sites of nosocomial infections
urinary tract, surgical wounds
adaptive (specific) immunity
mount defense against particular infectious agents by responses to that agent
innate (nonspecific) immunity
immunity exists in an organism because genetically determined characteristics
B cells
lymphocytes that are processed and mature
T cells
cells in thymus that undergo differentiation into thymus-derived cells