Pharmacology(General Pharmacology) Flashcards


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created 6 weeks ago by Sophmore
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1

Whats nystatin

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A suspension, local -> topical-> oral cavity drug

2
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Whats this used for

Antifungi

3
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Whats clotrimazole used for

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As a troche for Oral thrush

4
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Whats this used for

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Herpes

5
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Whats this used for

The ointment/ jelly both contain 5% of it while the spray contains 10% but they all used for topical anaesthesia

6
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Whats this used for

Local-> topical-> GI tract, used for sterlizing the gut before surgery

7
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Whats this used for

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Local-> topical-> Rectum-> retention enema, used in ulcerative colitis

8
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Whats this used for

Local-> topical-> rectum-> suppository, used bowel evacuation(cleaning the rectal channel)

9
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Local-> topical-> eye, ear and nose: as eye/ear drops

10
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Local-> topical-> bronchi: bronchial asthma and chronic obstructive pulmonary disease

11
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Local-> topical-> skin: cutaneous candidiasis(fungi infection of the skin)

12
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Local-> deep tissue: rheumatoid arthritis

13

What are the advantages of systematic oral routes

  • Safe
  • Cheap
  • Painless
  • Good for repeated and prolonged use
  • Self-administrered(taken by yourself)

14

What are the disadvantages of oral routes

Not suitable for:

  • emergency, the onset(time for the drug to begin its effect) is slow
  • Irritating drugs
  • Unabsorbable drugs(aminoglycosides)
  • Drugs that pass first pass metabolism(Insulin, lignocaine)
  • unconscious patients
  • Uncooperative patients
  • Patients with severe vomiting or diarrhea

15

Whats the advantages of sublingual routes

  • Quick onset
  • You can stop the effect by taking out the tablet
  • Passes first pass metabolism
  • Self-administrered(taken by yourself)

16

Whats the disadvantages of sublingual routes

Not suitable:

  • Irritating drugs
  • Drugs that don't dissolve in lipids(because cells have lipid membrane and if drugs aren't soluble in lipids, they can't pass through it)
  • Drugs that have a bad smell of taste

17

What are the advantages of pareternal routes

Good patients who:

  • Are Unconscious
  • Are Uncooperative
  • with vomiting and diarrhea

God for drugs that:

  • Are irritating
  • Pass first pass metabolism
  • Aren't absorbed orally

18

What are the disadvantages of pareternal routes

  • They need aseptic conditions(The procedure/ injection must be done in free from fungi, microorganism conditions(clean))
  • The clean condition it needs is expensive
  • its invasive(invades, enters the body by cutting or penetrating the skin)
  • Can't be Self-administrered
  • Could cause local tissue, nerves or vessels injury