Nucleus
control center that contains DNA in the form of chromosomes and chromatin
Nucleolus
assembles ribosomes
Plasma membrane
encloses cell contents and participate in many cellular activities required for life
Ribosomes
site of protein synthesis
Rough ER
contains ribosomes and synthesizes proteins that are inserted into the plasma membrane or exported out of the cell to go to other areas of the body
Smooth ER
site of lipid synthesis
Golgi apparatus
sort and modify proteins and lipids
Lysosome
contains enzymes that break down carbohydrates, lipids, and proteins
Centriole
Rod shaped bodies near the nucleus that helps to organize and divide cells contents during mitosis
Mitochondria
powerhouse of the cell and site of aerobic cellular respiration
Peroxisome
contains peroxide to eliminate cancer-causing free radicals
Vesicle
small, membranous pound sacs which move items into and out of the cell
Cytoplasm
material that fills the cell from the nuclear membrane to the plasma membrane
Cytosol
the fluid portion of the cytoplasm that is a suspension of nutrients, enzymes, and electrolytes
Cytoskeleton
the cell skeleton filled with proteins that support the cell
Give 3 life functions of the body
maintain boundaries, movement, reproduction, metabolism, exertion, responsiveness/excitability, digestion, and growth
6 levels of organization in order
chemical, cells, tissue, organs, systems,and organism
what are the differences between Catabolism and Anabolism?
Catabolism- complex substances are broken down into smaller pieces.
Anabolism- smaller pieces are made into more complex substances synthesis.
Endocrine is the same as hormone system?
True or false
true
How many bones are there in the body?
206 bones
What is it called when complex substances are broken down into smaller pieces?
Catabolism
When the body needs energy it breaks down what substance into two smaller substances?
adenosinetriphosphate (ATP)
what are the four basic types of tissue?
Nervous, connective, muscle, epithelium.
What function of the body is occurring when foodstuff is broken down into simple molecules that can be absorbed into the bloodstream?
Digestion
choose the answer that gives the six levels of organization largest to smallest?
Organisms, system, organs, tissues, cell, atoms.
What does a buffer do?
it helps to maintain a constant pH
What is the most abundant and important inorganic compound in the body?
Water
What is the pH of human blood?
pH 7.35 – 7.45
What are the names of four elements that 96% of the body consists of?
hydrogen, sodium, oxygen, calcium
What is a catalyst in biology?
protein enzymes
An example of extracellular fluid is blood?
true or false
true
All organic compounds contain nitrogen?
true or false
false
________ is the universal solvent.
Water
Alkalosis is when a person's blood pH is higher than within the acceptable range.
True or false
true
Disaccharides contain two simple sugars.
true or false
true
all these statements regarding ATP are true except (choose one)
A. ATP is a nucleotide.
B. It is the primary molecule responsible for providing energy use by all body cells.
C. ATP contains a phosphorus base, sugar and a phosphate group.
D. ATP contains three phosphate group.
C. ATP contains a phosphorus base, sugar and a phosphate group.
Complementary bases in RNA include A, G, C, and T.
true or false
false
the three types of RNA are messenger (mRNA), transfer (tRNA), and ribonucleic (rRNA)
true or false
true
in DNA, what types of bonds hold nucleotides together?
Hydrogen
the following statement regarding molecular chaperones are true except (choose one)
A. They help proteins achieve their functional 3-D structure
B. They aid in the folding and Association process of protein.
C. They are closely related to globular proteins.
D. They promote the breakdown of damaged or denatured proteins.
C. They are closely related to globular proteins.
Growth is usually accomplished by ink creasing the number of_________?
Cell
When it comes to the five survival needs, appropriate balance is not necessary, too much or too little is fine.
True or false
false
All but one of the listed is essential to survival needs, which is not in the group?
A. Oxygen
B. Carbon dioxide
C. Water
D. Nutrients
B. Carbon dioxide
There are twelve structural systems?
True or false
false
Which body system is a functional system?
A. Immune system
B. Skeleton system
C. Integumentary system
D. Nervous system
A. Immune system
the build up of smaller pieces into larger more complex substance is known as?
Anabolisim
The sum of all chemical reactions that occur within the body is known as metabolism?
true or false
true
ATP is known as_________ currency in the body?
A. Hormone
B. Krebs cycle
C. Energy
D. Immune
C. energy
Name three of the eight life functions of the body.
A. Maintain boundaries
B. Movement
C. Responsiveness/excitability
D. Digestion
E. Metabolism
F. Excretion
G. Reproduction
H. Growth
There are five basic types of tissue in the body.
true or false
false
Fluids outside of the cell are extracellular, and fluids inside a cell are intracellular.
true or false
false
Standard anatomical position is a body laying down feet together.
true or false
false
Two types of compounds occur in the human body, organic and inorganic. Organic compounds contain?
A. Water
B. Salt
C. Acid
D. Carbon
D. Carbon
The most abundant and import an organic compound in the human body is.
A. Blood
B. Water
C. Salt
D. Oxygen
B. Water
A person's pH level should be between 7.35 and 7.45.
true or false
true
match the terms to the definition:
terms definitions
A. Hydrophilic A. Proton acceptor
B. Acid B. body fluids pH
C. Buffer <7.35
D. Alkalosis C. Water loving
E. Hydrophobic D. Helps maintain a
F. Base constant pH
G. Acidosis E. Body fluids pH >
7.45
F. proton donor
G. Water fearing
A.hydrophilic C. Water loving
B. acid F. proton donor
C. Buffer D. Help maintains a constant pH
D. Alkalosis E. Body fluids pH > 7.45
E. Hydrophobic G. Water fearing
F. Base A. proton acceptor
G. Acidosis B. Body fluids pH < 7.35
What are the four most common elements in the human body? In fact, 96% of the body can system of these four elements. remember CHON
carbon, hydrogen, oxygen, and nitrogen.
Starch and Glycogen are two important _____ ______ in the body. They’re also both used as storage carbohydrates. ________ is the storage carbohydrate in animal tissues, and _______ is the storage carbohydrate in plants.
Polysaccharides
Glycogen
Starch
Important Disaccharides
a. Glucose and Fructose=____________ (Table sugar)
b. Glucose and _______= Maltose (Malt sugar) *
c. Glucose and Galactose = _______ (Milk sugar)
*Sucrose
Glucose
*Lactose
What is the H: O ratio in Carbohydrates?
2:1
Is the most efficient and compact form of store energy, fat for insulation?
Triglyceride
This are modified triglycerides, these are unique and it is why they form the cell membrane, these are diglycerides with a phosphorus-containing group and two fatty acid chains?
Phospholipids
It is essential for human like, it is found in cell membranes and is the raw material for vitamin D synthesis, these are flat molecules made of four interlocking hydrocarbon rings?
Steroids
This is a modified simple sugar (alcohol sugars)?
Glycerol
Single covalent bonds between carbon atoms are saturated and are solid at room temperature?
Saturation
The term best describing a state of internal balance is?
Homeostasis
True of False. 1. An example of homeostasis in the body is consuming large amounts of sugar daily over long periods of time and creating type II diabetes.
*False, homeostatic imbalance
True or False. . Blood and plasma are intracellular.
*False, extracellular
Which is the final piece in maintaining homeostatic control?
response
Negative feedback is _________ ___________ of something
To much
Stimulus-receptor-________-control center-__________-response
*afferent *efferent
Growth is usually accomplished by increasing the number of ________.
cells
T or F When it comes to the five survival needs, appropriate balance is not necessary, too much or too little is fine.
False
All but one of the listed is essential to survival needs, which is not in the group?
A.) Oxygen
B.) Carbon Dioxide*
C.) Water
D.) Nutrients
*B.) Carbon Dioxide*
T or F There are twelve structural systems.
False
Which body system is a functional system?
Immune System
T/F An example of homeostasis in the body is consuming large amounts of sugar daily over long periods of time and creating type II diabetes.
*False, homeostatic inbalance
Blood and plasma are intracellular?
False, extracellular
Which is the final piece in maintaining homeostatic control? a.effector b.response c.stimuli d. output
b. response
Negative feedback is _________ ___________ of something
to much
Stimulus-receptor-________-control center-__________-response
*afferent *efferent
Which of the following is NOT one of the functions of the integumentary system?
a) Protection
b) Blood Reservoir
c) Excretion
d) Detoxification
e) Sensory information
d) Detoxification
Which type of sensory receptor is NOT located in the skin?
a. Sound
b. Touch
c. Pressure
d. Free Nerve Endings
A. sound
Which of the following properties help to maintain hydration of the skin?
a. Keratin
b. Melanocyte
c. Sebum
d. A and B
e. A and C
e. A and C
Which of the following is NOT considered to be part of the integumentary system?
a. Skin
b. Teeth
c. Hair
d. Nails
e. Glands
b. Teeth
Which of the following layers are considered part of the SKIN?
a. Epidermis
b. Dermis
c. Subcutaneous layer
d. All of the above
e. A and B
e. A and B.
Which of the following are the correct characteristics for recognizing melanoma?
a. Apex, Border, Color, Direction
b. Asymmetry, Broad, Consistency, Diameter
c. Apex, Broad, Consistency, Direction
d. Asymmetry, Border, Color, Diameter
d. Asymmetry, Border, Color, Diameter
Which is the most common type of skin cancer?
Basal Cell Carcinoma
Which is the most dangerous type of skin cancer?
Melanoma
Which type of skin cancer arises from keratinocytes?
Squamous Cell Carcinoma
Which of the following is NOT considered important in skin care?
a. Proper nutrition
b. Adequate circulation
c. Adequate amounts of sunlight are important
d. Protection from sunlight
e. All are considered important
e. All are considered important
The RULE of NINES applies to what type of skin condition?
Burns
Which of the following is NOT a factor that affects wound healing?
a. Nerve Supply
b. Temperature
c. Infection
d. Blood Supply
e. Age
b. Temperature
For HAIR, which of the three concentric rings of keratin is responsible for forming a single later of overlapping cells, like shingles on a roof; helps to separate hairs so matting doesn’t occur, and is responsible for split ends.
Cuticle
Which of the following is NOT a function of HAIR?
a. Sensory perception
b. Guarding the scalp against trauma
c. Guarding the scalp against heat loss
d. Guarding the scalp against bacteria
e. Guarding the scalp against sunlight
d. Guarding the scalp against bacteria
What is the involuntary muscle responsible for goosebumps?
Arrector pili
What is the an extension of the dermis, into the epidermis that allows blood vessels to get closer to the superficial surface and is responsible for preventing slipping when grasping and object?
Dermal papillae
Which of the following are not specialized apocrine glands?
a. Mammary Glands
b. Ceruminous Glands
c. Sebaceous Glands
d. Eccrine Glands
e. C and D
e. C and D
Which of the following are derivatives of the epidermis?
a) Sudoriferous
b) Sebaceous)
c) Hair and hair follicles
d) Nails
e) All of the above
e) All of the above
Which of the following functions help in temperature regulation internally?
a. Constriction (narrow) of blood vessels
b. Dilation (widen) of blood vessels
c. Evaporation of perspiration
d. Changing environment
e. A, B and C
e. A, B and C
Which of the following is the correct order for Epidermal layers from superficial to deep?
a. Stratum spinosum, stratum lucidum, stratum basale, stratum granulosum, stratum coreum
b. Stratum corneum, stratum lucidum, stratum gransulosum, stratum spinosum, stratum basale
c. Stratum basale, stratum lucidum, stratum spinosum, stratum granulosum, stratum corneum
d. Stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, stratum corneum
b. Stratum corneum, stratum lucidum, stratum gransulosum, stratum spinosum, stratum basale*
Apocrine and Eccrine glands are types of which gland?
Sudoriferous
This layer of the dermis had areolar connective tissue, had dermal papillae, and is leaves room for defense for the cell to respond to foreign invaders?
Papillary Layer
Flexure lines are dermal folds near a joint, (visible lines on the palm of the hand) where the dermis is tightly secured to deeper structures. Which layer of the dermis are flexure lines present in?
a. Papillary Layer
b. Reticular Layer
c. Hypodermis
d. Cleavage Lines
e. Pigmented nevi
Match the
b. Reticular Layer
Means “horn”; the fibrous protein that helps give the epidermis its protective properties; rise in the layers and eventually sluff off as dead cells.
B. Keratinocyte
Spider shaped epithelial cells; means “black”; forms a pigment that shields and protects the nucleus from the damaging effects of UV radiation.
A. Melanocyte
Arise from BONE MARROW and migrate to the epidermis; ingest foreign substances and are key activators of the immune system
D. Dendritic or Langerhans Cells
Present at the epidermal-dermal junction; spiky hemisphere shape; associated with a sensory nerve ending for touch
C. Merkel (Tactile) Cells
Main skin pigment, found in hair, eyeball, iris of the eye, tumors. The darker the skin, the more pigments are found in their tissues
Melanin
Pigment that carries oxygen in RBCs
Hemoglobin
Related to vitamin A, stores in fatty tissues. Derived from carrots and other orange and yellow vegetables.
Carotene
Pigment responsible for the yellowing in jaundice, green appearance
Bile Pigments
Most superficial layer; 20-30 layers of dead cells represented only by sacs filled with keratin.
Stratum Corneum
Several layers of cells containing thick bundles of “spines” made of pre-keratin.
Stratum Spinosum
Three to five layers of flattened cells, organelles deteriorating; cytoplasm full of keratin granules
Stratum Granulosum
Deepest epidermal layer; one layer of active mitotic stem cells; some newly formed cells become part of the more superficial layers; see occasional melanocytes and epidermal dendritic cells.
Stratum Basale
A few rows of flat, dead keratinocytes; Found only in “thick skin” (palms, soles)
Stratum Lucidum
Type of gland that is confined to axillary and anogenital (relating to anus and genitals) areas; sweat contains fatty substances and proteins that lead to odor, but does not regulate temperature
Apocrine Gland
Type of gland that is abundant on palms, soles, and forehead; ducts connect to pores; function in thermoregulation
Eccrine Gland
Sweat gland; coiled glands that vent directly to the skin surface or through hair follicles.
Sudoriferous Gland
Sac-like gland associated with hair follicles; secrete sebum, an oily substance that lubricates and water proofs the skin
Sebaceous Gland
True or False; simple diffusion uses kinetic energy.
True
True or False; Active transport uses ATP
True
True or False; Exocytosis is the excretion of substances inside the cell
False
Which of the following processes require ATP
a. Endocytosis
b. Exocytosis
c. Active transport
d. All the above
d. All the above
True or False; Sodium and Chloride are most prominent inside the cell.
False
True or False? Ions diffuse according to their chemical gradient.
True
True or False? In vesicular transport, ATP is needed to transport large particles, macromolecules, and fluids across plasma membranes.
True
Exocytosis secretes large substances ___________ of the cell.
out
Endocytosis transports large materials _________ of the cell
into
The Na+ K+ pump pumps
3 Na+ ions out of cell and 2 K+ ions into cell
What are the two types of active processes?
Active transport, Vesicular transport
Ribosomes our site of protein synthesis. What are the two types?
Free ribosomes, Membrane bound ribosomes
What is mitochondria?
Mitochondria is known as the powerhouse of a cell.
True or False? Transcytosis is moving substance into, across, and then out of the cell.
True
Potassium and Calcium are most prominent outside the cell.
False
When a parent cell becomes two identical daughter cells called somatic cells is called?
Mitosis
The divistion of the cytoplasm”cell movement” begins in late anaphase, Microfilaments for the cleavage furrow and separate the cell?
Cytokenesis
Glycolysis-2ATP, Krebs cycle 32 – 34 ATP, electron transport chain and oxidative phosphorylation are pathways Of?
Cellular respiration*
DNA transfers information to RNA is a process called?
Transcription
The process by which amino acids are assembled into a protein?
Translation
True/False: When a cell is preparing to divide, the chromatin threads coil and condense into short, bar-like bodies called chromosomes
A. True
True
True or False? There are 4 phases of mitosis. They include all of the following EXCEPT (multiple choice):
a. telophase
b. metaphase
c. interphase
d. anaphase
e. prophase
“C” interphase – this is the period from cell formation to cell division. It is NOT a phase of mitosis.
Fill in the blank. Name the three pathways in which glucose is catabolized:
Glycolysis, Krebs Cycle, electron transport chain
True/False: Transcription is the process by which amino acids are assembled into a protein.
False Translation
Translation occurs in the _____________, whereas transcription occurs in the ___________.
Translation: cytoplasm, Transcription: ribosome
The cell membrane is permeable to some substances but not to others. What characteristics does this describe?
Semipermeable
In passive movement through the plasma membrane, molecules move ________ the concentration gradient.
Down
When constant movement of particles go from an area of higher concentration to an area of lower concentration until equilibrium is reached, it is considered what type of passive process?
diffusion
T/F A molecule will diffuse through a membrane when the molecule is lipid soluble.
true
When it comes to simple diffusion, ________ and gasses move freely across the lipid membrane.
Lipids
True or False. A membrane lipid consists of 20% glycolipids.
False 5%
The cells are bathes in an extracellular fluid called _____________ that is derived from the blood
Interstitial fluid
What are the 2 movement through the PM and what is the difference between them two?
Passive- does not require energy
Active- requires energy
True or False. Atom is the smallest structural and functional living unit.
False cell
Constant movement of particles from an area of higher concentration to lower concentration until they each equilibrium is called?
Diffusion
The diffusion of water through a selectively membrane is called __________
Osmosis
true or false The passage of a solution through a membrane under mechanical force is called diffusion
false filtration
solution that has a lower concentration than the fluid within the cell is called __________.
hypotonic
An organelle that produces energy for the cell is called a ________________.
Mitochondrion
If a cell lacked centrioles, it would not be able to _________________.
divide
Membrane lipids are composed of:
Phospholipids, Glycolipids
Cholesterol
True or False The term used to describe the cell membrane is the fluid mosaic model.
True
Unsaturated fat is ________ at room temperature
liquid
The job of the plasma membrane is:
a) Enclosing cell contents
b) Separates major body fluids (ICF and ECF)
c) Participates in activities like growth, reproduction, and cellular communication
d) Absorbs materials from extracellular environment
e) All of the above
e) All of the above
The Sodium-Potassium Pump is one form of active transport. This system pumps __*__ Na+ ions __*__of the cell and __*__ K+ ions ___*__ the cell with each cycle.
3 Na ions out of cell
2 K ions into the cell
What is the average resting membrane potential of a cell?
-70mV the average resting membrane potential is -70mV. (The range is -50 to -100mV depending on the cell type)
What part of the cell is responsible for lipid synthesis?
Smooth Endoplasmic Reticulum
Peroxisomes are responsible for breaking down; these are considered carcinogens, meaning cancer causing.
Free radicals
What are the phases of Mitosis?
I. Anaphase II. Prophase III. Metaphase IV. Interphase V. Telophase
a. I, III, V
b. I, II, IV
c. I, II, III, V*
d. IV only
C- (proper order of cell division) Prophase, Metaphase, Anaphase, Telophase
True or False? Pinocytosis is “cell drinking”.
true
Sodium follows its concentration gradient and brings the cell up to ______, the actual resting potential of the cell.
-70mV
The material that fills a cell – a suspension of nutrients, electrolytes, enzymes, and other materials in water.
cytoplasm
*True or False? Mitochondria contain their own DNA, and are known as the “power houses” of a cell.
true
Choose the correct order, from beginning to end, of the 4 phases of mitosis.
A. Anaphase, Prophase, Metaphase, Telophase
B. Telophase, Anaphase, Prophase, Metaphase
C. Prophase, Anaphase, Telophase, Metaphase
Choose the correct order, from beginning to end, of the 4 phases of mitosis.
A. Anaphase, Prophase, Metaphase, Telophase
B. Telophase, Anaphase, Prophase, Metaphase
C. Prophase, Anaphase, Telophase, Metaphase
D. Prophase, Metaphase, Anaphase, Telophase
D. Prophase, Metaphase, Anaphase, Telophase*
What is the correct order for transcription/ translation?
a. DNA unwinds, RNA nucleotide bases will semi-conservatively replicate by matching the RNA bases to the DNA bases. This forms the mRNA copy of DNA.
b. A ribosomal subunit, rRNA, joins the mRNA copy of DNA. A START CODON on the mRNA strand attaches to the start codon of tRNA. The mRNA strand will move along the A,P,E sites of the rRNA subunit andmore tRNA will attach their amino acid to the newly formed polypeptide chain trailing from the mRNA, rRNA complex.
c. The newly formed polypeptide will go to the RoughER for processing and molecular chaperones will fold the protein, giving it the 3-D shape
1,2,3
True or False? Both Transcription and Translation have a an initiation phase, an elongation phase and a termination phase?
True
The process by which amino acids are assembled into a protein is called?
Translation
NaK ATPase moves __________ Na out of the cell and _________ K into the cell on every cycle or turn.
3, 2
Which ions are higher outside of the cell?
Sodium and Chloride
The most accurate term used to describe the plasma membrane is called _____________?
Fluid Mosaic Model
Which of the following types of membrane transport requires ATP?
a. Osmosis
b. Facilitated diffusion
c. Active Transport
d. Bulk transport or vesicular transport
e. C and D are both correct
e. C and D are both correct
Match the correct percent to the type of membrane lipid.
173. Phospholipids
174. Glycolipids
175. Cholesterol
A. 5%
B. 20%
C. 75%
D. 30%
173 C
174 A
175 B
A protein built into the plasma membrane that will have its active site exposed to substances in the adjacent solution. This protein type may act as a team with other proteins to induce sequential steps in a metabolic pathway.
Enzymatic Activity
A protein that spans the membrane and may provide a channel across the membrane that is selective for a particular solute. Some use ATP as an energy source, like NaK ATPase.
Transport
Membrane proteins of adjacent cells that may be hooked together by intercellular junctions. They may act as temporary binding sites that guide cell migration and other cell-to-cell interaction.
Intercellular Joining
A membrane protein exposed to the outside of the cell that may have a binding site with a specific shape that fits the shape of a chemical messenger, such as a hormone.
Receptors for signal transduction
Cytoskeleton and extracellular matrix may be anchored to the membrane proteins to help maintain cell shape and fix the location of certain membrane proteins.
Attachment to the cytoskeleton and extracellular matrix
Period from cell formation to cell division
Interphase
Third phase of mitosis. Each half of the “x” chromosome gets pulled toward the opposite poles, now looking “v” shaped.
Anaphase
Means “cell movement”, the division of the cytoplasm
Cytokinesis
Vigorous growth and metabolism phase
G1
Preparation for cell division
G2
The final phase of mitosis in which identical sets of chromosomes at opposite ends uncoil and resume their thread-like chromatin form; the cell will temporarily have two nuclei
Telophase
DNA replication occurs
S phase
The first phase of mitosis; chromatin condenses and centrtioles attach to the chomosome , starting to line them up at the center of the cell
Prophase
The second stage of mitosis; chromosomes cluster at the mid-line of the cell at the equator and the chromosomes start separating from on another.
Metaphase