ch 5
1) Humans and mice differ because
Answer:
Topic: Concept 5.1
Skill: Knowledge/Comprehension
D
2) Molecules with which functional groups may form polymers via dehydration reactions?
Answer:
Topic: Concepts 5.1, 4.3
Skill: Application/Analysis
E
3) Which of these molecules is not formed by dehydration reactions?
Answer:
Topic: Concept 5.1
Skill: Knowledge/Comprehension
A
4) In animal metabolism, most of the monomers released by digestion of food macromolecules are metabolized to provide energy. Only a small portion of these monomers are used for synthesis of new macromolecules. The net result is that
Answer:
Topic: Concept 5.1
Skill: Application/Analysis
B
5) Which of these classes of biological molecules consist of both small molecules and macromolecular polymers?
Answer:
Topic: Concept 5.1
Skill: Knowledge/Comprehension
B
6) Which of the following is not a polymer?
Answer:
Topic: Concept 5.1
Skill: Knowledge/Comprehension
A
7) What is the chemical reaction mechanism by which cells make polymers from monomers?
Answer:
Topic: Concept 5.1
Skill: Knowledge/Comprehension
C
8) How many molecules of water are needed to completely hydrolyze a polymer that is 11 monomers long?
Answer:
Topic: Concept 5.1
Skill: Knowledge/Comprehension
C
9) Which of the following best summarizes the relationship between dehydration reactions and hydrolysis?
Answer:
Topic: Concept 5.1
Skill: Knowledge/Comprehension
10) Which of the following polymers contain nitrogen?
Answer: D
Topic: Concept 5.2
Skill: Knowledge/Comprehension
11) The molecular formula for glucose is C6H12O6. What would be the molecular formula for a molecule made by linking three glucose molecules together by dehydration reactions?
Answer: B
Topic: Concept 5.2
Skill: Application/Analysis
12) The enzyme amylase can break glycosidic linkages between glucose monomers only if the monomers are the α form. Which of the following could amylase break down?
Answer: A
Topic: Concept 5.2
Skill: Knowledge/Comprehension
13) On food packages, to what does the term insoluble fiber refer?
Answer: A
Topic: Concept 5.2
Skill: Knowledge/Comprehension
14) A molecule with the chemical formula C6H12O6 is probably a
Answer: E
Topic: Concept 5.2
Skill: Knowledge/Comprehension
15) Lactose, a sugar in milk, is composed of one glucose molecule joined by a glycosidic linkage to one galactose molecule. How is lactose classified?
Answer: D
Topic: Concept 5.2
Skill: Knowledge/Comprehension
16) All of the following are polysaccharides except
Answer: A
Topic: Concept 5.2
Skill: Knowledge/Comprehension
17) Which of the following is true of both starch and cellulose?
Answer: A
Topic: Concept 5.2
Skill: Knowledge/Comprehension
18) Which of the following is true of cellulose?
Answer: D
Topic: Concept 5.2
Skill: Knowledge/Comprehension
19) Humans can digest starch but not cellulose because
Answer: C
Topic: Concept 5.2
Skill: Knowledge/Comprehension
20) Which of the following statements concerning saturated fats is not true?
Answer: B
Topic: Concept 5.3
Skill: Knowledge/Comprehension
21) A molecule with the formula C18H36O2 is probably a
Answer: B
Topic: Concept 5.3
Skill: Knowledge/Comprehension
22) Which of the following statements is true for the class of biological molecules known as lipids?
Answer: A
Topic: Concept 5.3
Skill: Knowledge/Comprehension
23) The label on a container of margarine lists "hydrogenated vegetable oil" as the major ingredient. What is the result of adding hydrogens to vegetable oil?
Answer: B
Topic: Concept 5.3
Skill: Knowledge/Comprehension
24) Which of the following is true regarding saturated fatty acids?
Answer: C
Topic: Concept 5.3
Skill: Knowledge/Comprehension
25) Large organic molecules are usually assembled by polymerization of a few kinds of simple subunits. Which of the following is an exception to this statement?
Answer: A
Topic: Concepts 5.1-5.3
Skill: Knowledge/Comprehension
26) Which modifications of fatty acids will best keep triglycerides solid at warmer temperatures?
Answer: D
Topic: Concept 5.3
Skill: Application/Analysis
27) Why are human sex hormones considered to be lipids?
Answer: B
Topic: Concept 5.3
Skill: Knowledge/Comprehension
28) All of the following contain amino acids except
Answer: B
Topic: Concepts 5.3, 5.4
Skill: Knowledge/Comprehension
29) The bonding of two amino acid molecules to form a larger molecule requires
Answer: A
Topic: Concept 5.4
Skill: Knowledge/Comprehension
30) There are 20 different amino acids. What makes one amino acid different from another?
Answer: C
Topic: Concept 5.4
Skill: Knowledge/Comprehension
31) The bonding of two amino acid molecules to form a larger molecule requires which of the following?
Answer: A
Topic: Concept 5.4
Skill: Knowledge/Comprehension
32) Polysaccharides, triacylglycerides, and proteins are similar in that they
Answer: B
Topic: Concepts 5.1-5.4
Skill: Application/Analysis
33) Dehydration reactions are used in forming which of the following compounds?
Answer: E
Topic: Concepts 5.1-5.4
Skill: Knowledge/Comprehension
34) Upon chemical analysis, a particular polypeptide was found to contain 100 amino acids. How many peptide bonds are present in this protein?
Answer: C
Topic: Concept 5.4
Skill: Knowledge/Comprehension
35) What aspects of protein structure are stabilized or assisted by hydrogen bonds?
Answer: E
Topic: Concept 5.4
Skill: Knowledge/Comprehension
36) How many different kinds of polypeptides, each composed of 12 amino acids, could be synthesized using the 20 common amino acids?
Answer: E
Topic: Concept 5.4
Skill: Application/Analysis
37) Which bonds are created during the formation of the primary structure of a protein?
Answer: A
Topic: Concept 5.4
Skill: Knowledge/Comprehension
38) What maintains the secondary structure of a protein?
Answer: B
Topic: Concept 5.4
Skill: Knowledge/Comprehension
39) Which type of interaction stabilizes the α helix and the β pleated sheet structures of proteins?
Answer: D
Topic: Concept 5.4
Skill: Knowledge/Comprehension
40) Which level of protein structure do the α helix and the β pleated sheet represent?
Answer: B
Topic: Concept 5.4
Skill: Knowledge/Comprehension
41) The amino acids of the protein keratin are arranged predominantly in an α helix. This secondary structure is stabilized by
Answer: E
Topic: Concept 5.4
Skill: Knowledge/Comprehension
42) The tertiary structure of a protein is the
Answer: C
Topic: Concept 5.4
Skill: Knowledge/Comprehension
43) What type of covalent bond between amino acid side chains (R groups) functions in maintaining a polypeptide's specific three-dimensional shape?
Answer: D
Topic: Concept 5.4
Skill: Knowledge/Comprehension
44) At which level of protein structure are interactions between the side chains (R groups) most important?
Answer: C
Topic: Concept 5.4
Skill: Knowledge/Comprehension
45) The R group or side chain of the amino acid serine is –CH2–OH. The R group or side chain of the amino acid leucine is –CH2–CH–(CH3)2. Where would you expect to find these amino acids in a globular protein in aqueous solution?
Answer: B
Topic: Concept 5.4
Skill: Application/Analysis
46) Misfolding of polypeptides is a serious problem in cells. Which of the following diseases are associated with an accumulation of misfolded polypeptides?
Answer: D
Topic: Concept 5.4
Skill: Knowledge/Comprehension
47) Changing a single amino acid in a protein consisting of 325 amino acids would
Answer: E
Topic: Concept 5.4
Skill: Application/Analysis
48) Normal hemoglobin is a tetramer, consisting of two molecules of β hemoglobin and two molecules of α hemoglobin. In sickle-cell disease, as a result of a single amino acid change, the mutant hemoglobin tetramers associate with each other and assemble into large fibers. Based on this information alone, we can conclude that sickle-cell hemoglobin exhibits
Answer: E
Topic: Concept 5.4
Skill: Application/Analysis
49) What methods may be used to elucidate the structures of purified proteins?
Answer: E
Topic: Concept 5.4
Skill: Knowledge/Comprehension
50) In a normal cellular protein, where would you expect to find a hydrophobic amino acid like valine?
Answer: D
Topic: Concept 5.4
Skill: Application/Analysis
51) Which of the following techniques uses the amino acid sequences of polypeptides to predict a protein's three-dimensional structure?
Answer: B
Topic: Concept 5.4
Skill: Knowledge/Comprehension
52) If cells are grown in a medium containing radioactive 35S, which of these molecules will be labeled?
Answer: C
Topic: Concept 5.4
Skill: Application/Analysis
53) What is the term used for a protein molecule that assists in the proper folding of other proteins?
Answer: B
Topic: Concept 5.4
Skill: Knowledge/Comprehension
54) DNAase is an enzyme that catalyzes the hydrolysis of the covalent bonds that join nucleotides together. What would first happen to DNA molecules treated with DNAase?
Answer: B
Topic: Concepts 5.1, 5.5
Skill: Knowledge/Comprehension
55) Which of the following statements about the 5' end of a polynucleotide strand of DNA is correct?
Answer: B
Topic: Concept 5.5
Skill: Knowledge/Comprehension
56) One of the primary functions of RNA molecules is to
Answer: B
Topic: Concept 5.5
Skill: Knowledge/Comprehension
57) If 14C-labeled uridine triphosphate is added to the growth medium of cells, what macromolecules will be labeled?
Answer: C
Topic: Concept 5.5
Skill: Application/Analysis
58) Which of the following descriptions best fits the class of molecules known as nucleotides?
Answer: C
Topic: Concept 5.5
59) Which of the following are nitrogenous bases of the pyrimidine type?
Answer: B
Topic: Concept 5.5
Skill: Knowledge/Comprehension
60) Which of the following are nitrogenous bases of the purine type?
Answer: B
Topic: Concept 5.5
Skill: Knowledge/Comprehension
61) If a DNA sample were composed of 10% thymine, what would be the percentage of guanine?
Answer: C
Topic: Concept 5.5
Skill: Application/Analysis
62) A double-stranded DNA molecule contains a total of 120 purines and 120 pyrimidines. This DNA molecule could be composed of
Answer: B
Topic: Concept 5.5
Skill: Application/Analysis
63) The difference between the sugar in DNA and the sugar in RNA is that the sugar in DNA
Answer: E
Topic: Concepts 5.2, 5.5
Skill: Knowledge/Comprehension
64) Which of the following statements best summarizes the differences between DNA and RNA?
Answer: C
Topic: Concept 5.5
Skill: Knowledge/Comprehension
65) If one strand of a DNA molecule has the sequence of bases 5'ATTGCA3', the other complementary strand would have the sequence
Answer: B
Topic: Concept 5.5
Skill: Application/Analysis
66) What is the structural feature that allows DNA to replicate?
Answer: B
Topic: Concept 5.5
Skill: Knowledge/Comprehension
67) A new organism is discovered in the forests of Costa Rica. Scientists there determine that the polypeptide sequence of hemoglobin from the new organism has 72 amino acid differences from humans, 65 differences from a gibbon, 49 differences from a rat, and 5 differences from a frog. These data suggest that the new organism
Answer: B
Topic: Concept 5.5
Skill: Application/Analysis
68) Which of the following is an example of hydrolysis?
Answer: D
Topic: Concepts 5.1-5.4
Skill: Knowledge/Comprehension
69) If cells are grown in a medium containing radioactive 32P-labeled phosphate, which of these molecules will be labeled?
Answer: E
Topic: Concepts 5.2-5.5
Skill: Application/Analysis
70) If cells are grown in a medium containing radioactive 15N, which of these molecules will be labeled?
Answer: E
Topic: Concepts 5.2-5.5
Skill: Application/Analysis
71) How will brief heating (to 95°C) affect macromolecular structures in aqueous solution?
Answer: E
Topic: Concepts 5.2, 5.4, 5.5
Skill: Application/Analysis
72) Which of the following is not a monomer/polymer pairing?
Answer: C
Topic: Concepts 5.2-5.5
Skill: Knowledge/Comprehension
73) If two molecules of the general type shown in Figure 5.1 were linked together, carbon-1 of one molecule to carbon-4 of the other, the single molecule that would result would be
Answer: A
Topic: Concept 5.2
Skill: Knowledge/Comprehension
74) Which of the following descriptors is true of the molecule shown in Figure 5.1?
Answer: E
Topic: Concept 5.2
Skill: Knowledge/Comprehension
75) Which of the following statements is true regarding the molecule illustrated in Figure 5.2?
Answer: D
Topic: Concept 5.3
Skill: Knowledge/Comprehension
76) Which of the following statements is true regarding the molecule illustrated in Figure 5.3?
Answer: C
Topic: Concept 5.3
Skill: Knowledge/Comprehension
77) The molecule shown in Figure 5.3 is a
Answer: E
Topic: Concept 5.3
Skill: Knowledge/Comprehension
78) What is the structure shown in Figure 5.4?
Answer: C
Topic: Concept 5.3
Skill: Knowledge/Comprehension
79) Which of the following statements is/are true regarding the chemical reaction illustrated in Figure 5.5?
Answer: B
Topic: Concept 5.4
Skill: Application/Analysis
80) At which bond would water need to be added to achieve hydrolysis of the peptide, back to its component amino acid?
Answer: C
Topic: Concept 5.4
Skill: Knowledge/Comprehension
81) Which bond is a peptide bond?
Answer: C
Topic: Concept 5.4
Skill: Knowledge/Comprehension
82) Which bond is closest to the amino terminus of the molecule?
Answer: A
Topic: Concept 5.4
Skill: Knowledge/Comprehension
83) The structure depicted in Figure 5.7 shows the
Answer: D
Topic: Concept 5.4
Skill: Knowledge/Comprehension
The following questions are based on the 15 molecules illustrated in Figure 5.8. Each molecule may be used once, more than once, or not at all.
Figure 5.8
84) Which molecule has both hydrophilic and hydrophobic properties and would be found in plasma membranes?
Answer: B
Topic: Concept 5.2
Skill: Knowledge/Comprehension
85) Which of the following combinations could be linked together to form a nucleotide?
Answer: D
Topic: Concept 5.5
Skill: Knowledge/Comprehension
86) Which of the following molecules contain(s) an aldehyde type of carbonyl functional group?
Answer: E
Topic: Concept 5.2
Skill: Knowledge/Comprehension
87) Which molecule is glycerol?
Answer: C
Topic: Concept 5.2
Skill: Knowledge/Comprehension
88) Which molecule is a saturated fatty acid?
Answer: E
Topic: Concept 5.3
Skill: Knowledge/Comprehension
89) Which of the following molecules is a purine type of nitrogenous base?
Answer: E
Topic: Concept 5.5
Skill: Knowledge/Comprehension
90) Which of the following molecules act as building blocks (monomers) of polypeptides?
Answer: B
Topic: Concept 5.4
Skill: Knowledge/Comprehension
91) Which of the following molecules is an amino acid with a hydrophobic R group or side chain?
Answer: B
Topic: Concept 5.4
Skill: Knowledge/Comprehension
92) Which of the following molecules could be joined together by a peptide bond as a result of a dehydration reaction?
Answer: C
Topic: Concept 5.4
Skill: Knowledge/Comprehension
93) A fat (or triacylglycerol) would be formed as a result of a dehydration reaction between
Answer: B
Topic: Concept 5.3
Skill: Knowledge/Comprehension
94) Which of the following molecules could be joined together by a phosphodiester type of covalent bond?
Answer: D
Topic: Concept 5.3
Skill: Knowledge/Comprehension
95) Which of the following molecules is the pentose sugar found in RNA?
Answer: D
Topic: Concept 5.5
Skill: Knowledge/Comprehension
96) Which of the following molecules contains a glycosidic linkage type of covalent bond?
Answer: E
Topic: Concept 5.2
Skill: Knowledge/Comprehension
97) Which of the following molecules has a functional group that frequently forms covalent bonds that maintain the tertiary structure of a protein?
Answer: A
Topic: Concept 5.4
Skill: Knowledge/Comprehension
98) Which of the following molecules consists of a hydrophilic "head" region and a hydrophobic "tail" region?
Answer: B
Topic: Concept 5.3
Skill: Knowledge/Comprehension
99) Which of the following statements is false?
Answer: E
Topic: Concepts 5.2-5.4
Skill: Knowledge/Comprehension
Approximately 32 different monomeric carbohydrate subunits are found in various natural polysaccharides. Proteins are composed of 20 different amino acids. DNA and RNA are each synthesized from four nucleotides.
100) Among these biological polymers, which has the least structural variety?
Answer: C
Topic: Concepts 5.2-5.5
Skill: Synthesis/Evaluation
Approximately 32 different monomeric carbohydrate subunits are found in various natural polysaccharides. Proteins are composed of 20 different amino acids. DNA and RNA are each synthesized from four nucleotides.
101) Which class of biological polymer has the greatest functional variety?
Answer: B
Topic: Concepts 5.2-5.5
Skill: Synthesis/Evaluation
Approximately 32 different monomeric carbohydrate subunits are found in various natural polysaccharides. Proteins are composed of 20 different amino acids. DNA and RNA are each synthesized from four nucleotides.
102) Professor Jamey Marth at the University of California, Santa Barbara, identified 70 molecules that are used to build cellular macromolecules and structures. These include at least 34 saccharides, 8 nucleosides, and 20 amino acids. In theory, then, which class of biological polymer has the greatest information-coding capacity?
Answer: A
Topic: Concepts 5.2-5.5
Skill: Synthesis/Evaluation
103) Which of the following categories includes all others in the list?
Answer: D
Topic: End-of-Chapter Questions
Skill: Knowledge/Comprehension
104) The enzyme amylase can break glycosidic linkages between glucose monomers only if the monomers are in the α form. Which of the following could amylase break down?
Answer: A
Topic: End-of-Chapter Questions
Skill: Knowledge/Comprehension
105) Which of the following statements concerning unsaturated fats is true?
Answer: B
Topic: End-of-Chapter Questions
Skill: Knowledge/Comprehension
106) The structural level of a protein least affected by a disruption in hydrogen bonding is the
Answer: A
Topic: End-of-Chapter Questions
Skill: Knowledge/Comprehension
107) Enzymes that break down DNA catalyze the hydrolysis of the covalent bonds that join nucleotides together. What would happen to DNA molecules treated with these enzymes?
Answer: B
Topic: End-of-Chapter Questions
Skill: Knowledge/Comprehension
108) The molecular formula for glucose is C6H12O6. What would be the molecular formula for a polymer made by linking ten glucose molecules together by dehydration reactions?
Answer: C
Topic: End-of-Chapter Questions
Skill: Application/Analysis
109) Which of the following pairs of base sequences could form a short stretch of a normal double helix of DNA?
Answer: D
Topic: End-of-Chapter Questions
Skill: Application/Analysis