Which of the following must exist in a population before natural selection can act upon that population?
A) genetic variation among individuals
B) variation among individuals caused by environmental factors
C) sexual reproduction
D) Three of the responses are correct.
E) Two of the responses are correct.

Answer: A

Within six months of effectively using methicillin to treat S. aureus infections in a community, all new infections were caused by MRSA. How can this result best be explained?
A) S. aureus can resist vaccines.
B) A patient must have become infected with MRSA from another community.
C) In response to the drug, S. aureus began making drug-resistant versions of the protein targeted by the drug.
D) Some drug-resistant bacteria were present at the start of treatment, and natural selection increased their frequency.
E) The drug caused the S. aureus DNA to change.

Answer: D

The rise of methicillin-resistant Staphylococcus aureus (MRSA) can be considered to be an example of artificial selection because
A) humans purposefully raise MRSA in large fermenters in an attempt to make the bacteria ever-more resistant.
B) S. aureus is cultivated by humans to replenish the soil with nutrients.
C) humans synthesize methicillin and create environments in which bacteria frequently come into contact with methicillin.
D) Humans are becoming resistant to bacteria by taking methicillin

Answer: C

Which of the following statements most detracts from the claim that the human appendix is a completely vestigial organ?
A) The appendix can be surgically removed with no immediate ill effects.
B) The appendix might have been larger in fossil hominids.
C) The appendix has a substantial amount of defensive lymphatic tissue.
D) Individuals with a larger-than-average appendix leave fewer offspring than those with a below-average-sized appendix.
E) In a million years, the human species might completely lack an appendix.

Answer: C

What must be true of any organ that is described as vestigial?
A) It must be analogous to some feature in an ancestor.
B) It must be homologous to some feature in an ancestor.
C) It must be both homologous and analogous to some feature in an ancestor.
D) It need be neither homologous nor analogous to some feature in an ancestor.

Answer: B

12) Which of the following is a true statement concerning genetic variation?
A) It is created by the direct action of natural selection.
B) It arises in response to changes in the environment.
C) It must be present in a population before natural selection can act upon the population.
D) It tends to be reduced by the processes involved when diploid organisms produce gametes.
E) A population that has a higher average heterozygosity has less genetic variation than one with a lower average heterozygosity.

Answer: C

25) Swine are vulnerable to infection by bird flu virus and human flu virus, which can both be present in an individual pig at the same time. When this occurs, it is possible for genes from bird flu virus and human flu virus to be combined, thereby producing a genetically distinctive virus, which can subsequently cause widespread disease.

The production of new types of flu virus in the manner described above is most similar to the phenomenon of
A) bottleneck effect.
B) founder effect.
C) natural selection.
D) gene flow.
E) sexual selection.

Answer: D

17) The role that humans play in artificial selection is to
A) determine who lives and who dies.
B) create the genetic variants, which nature then selects.
C) choose which organisms breed, and which do not.
D) train organisms to breed more successfully.
E) perform artificial insemination.

Answer: C

23) Of the following anatomical structures, which is homologous to the bones in the wing of a bird?
A) cartilage in the dorsal fin of a shark
B) bones in the hind limb of a kangaroo
C) chitinous struts in the wing of a butterfly
D) bony rays in the tail fin of a flying fish
E) bones in the flipper of a whale

Answer: E

24) If two modern organisms are distantly related in an evolutionary sense, then one should expect that
A) they live in very different habitats.
B) they should share fewer homologous structures than two more closely related organisms.
C) their chromosomes should be very similar.
D) they shared a common ancestor relatively recently.
E) they should be members of the same genus.

Answer: B

6) In modern terminology, diversity is understood to be a result of genetic variation. Which of the following is a recognized source of variation for evolution?
A) mistakes in translation of structural genes
B) mistakes in protein folding
C) rampant changes to the dictionary of the genetic code
D) binary fission
E) recombination by crossing over in meiosis

Answer: E

14) Whenever diploid populations are in Hardy-Weinberg equilibrium at a particular locus
A) the allele's frequency should not change from one generation to the next, but its representation in homozygous and heterozygous genotypes may change.
B) natural selection, gene flow, and genetic drift are acting equally to change an allele's frequency.
C) this means that, at this locus, two alleles are present in equal proportions.
D) the population itself is not evolving, but individuals within the population may be evolving.

Answer: A

15) In the formula for determining a population's genotype frequencies, the 2 in the term 2pq is necessary because
A) the population is diploid.
B) heterozygotes can come about in two ways.
C) the population is doubling in number.
D) heterozygotes have two alleles.

Answer: B

16) In the formula for determining a population’s genotype frequencies, the pq in the term 2pq is necessary because
A) the population is diploid.
B) heterozygotes can come about in two ways.
C) the population is doubling in number.
D) heterozygotes have two alleles.

Answer: D

18) In a Hardy-Weinberg population with two alleles, A and a, that are in equilibrium, the frequency of the allele a is 0.3. What is the percentage of the population that is homozygous for this allele?
A) 0.09
B) 0.49
C) 0.9
D) 9.0
E) 49.0

Answer: D

19) In a Hardy-Weinberg population with two alleles, A and a, that are in equilibrium, the frequency of allele a is 0.2. What is the percentage of the population that is heterozygous for this allele?
A) 0.2
B) 2.0
C) 4.0
D) 16.0
E) 32.0

Answer: E

20) In a Hardy-Weinberg population with two alleles, A and a, that are in equilibrium, the frequency of allele a is 0.1. What is the frequency of individuals with AA genotype?
A) 0.20
B) 0.32
C) 0.42
D) 0.81
E) Genotype frequency cannot be determined from the information provided.

Answer: D

39) The recessive allele that causes phenylketonuria (PKU) is harmful, except when an infant's diet lacks the amino acid phenylalanine. What maintains the presence of this harmful allele in a population's gene pool?
A) heterozygote advantage
B) stabilizing selection
C) diploidy
D) balancing selection

Answer: C

9) Two species of frogs belonging to the same genus occasionally mate, but the offspring fail to develop and hatch. What is the mechanism for keeping the two frog species separate?
A) the postzygotic barrier called hybrid inviability
B) the postzygotic barrier called hybrid breakdown
C) the prezygotic barrier called hybrid sterility
D) gametic isolation

Answer: A

Theoretically, the production of sterile mules by interbreeding between female horses (mares) and male donkeys (jacks) should
A) result in the extinction of one of the two parental species.
B) cause convergent evolution.
C) strengthen postzygotic barriers between horses and donkeys.
D) weaken the intrinsic reproductive barriers between horses and donkeys.
E) eventually result in the formation of a single species from the two parental species.

Answer: C

18) The difference between geographic isolation and habitat differentiation is the
A) relative locations of two populations as speciation occurs.
B) speed (tempo) at which two populations undergo speciation.
C) amount of genetic variation that occurs among two gene pools as speciation occurs.
D) identity of the phylogenetic kingdom or domain in which these phenomena occur.
E) the ploidy of the two populations as speciation occurs.

Answer: A

11) When male horses (stallions) and female donkeys (jennets) mate, they produce a sterile hybrid called a hinny. Hinnies occur much less frequently than do mules, but are just as healthy and robust as mules. Logically, which of the following best accounts for the relative rarity of hinnies, and what kind of prezygotic isolating mechanism is at work here?
A) Most hinnies die during fetal development; reduced hybrid viability.
B) Most hinnies die soon after being born; hybrid breakdown.
C) Most hinnies are reproductively sterile; reduced hybrid fertility.
D) Stallions and jennets are choosier about their mating partners than are mares and jacks; behavioral isolation.
E) Stallions and jennets are choosier about their mating partners than are mares and jacks; gametic isolation.

Answer: D