BCH 100 Lecture 13+14: Glycolysis
Importance of Glucose
Makes fantastic fuel! Lots of energy, stored as glycogen, provides carbon skeletons for all amino acids, membrane lipids, nucleotides and metabolic cofactors. The most stable hexose so it has a low tendency to glycosylate proteins
Where does Glycolysis happen?
In the cytosol of all cells including red blood cells
What are the 10 structures of Glycolysis going fowards?
Glucose -> Glucose-6-Phosphate -> Fructose-6-Phosphate -> Fructose-1,6- Bisphosphate -> Dihyroxyacetone Phosphate + Glyceraldehyde Phosphate -> 1,3-bisphosphoglycerate -> 3-phosphoglycerate -> 2-phosphoglycerate -> Phosphoenol Pyruvate -> Pyruvate
What are the kinases and enzymes involved in the forward reaction of Glycolysis?
Hexokinase -> Phosphohexose isomerase ->Phosphofructo kinase -> aldolase/ + triose phosphate isomerase -> GAP DH (dehydrogenase) -> Phosphoglycerate kinase -> Phosphoglycerate mutase -> enolase -> pyruvate kinase