Anti inflammatory drugs for the respiration system

SLM

• S - steroids (beclomethasone)
• L - leukotriene inhibitors (montelukast)
• M - mast cell stabilizers (cromolyn)

inhaled glucosteroids

• beclomethasone
• budesonide
• fluticasone propinate
• mometasone furoate

PO glucosteroids

• prednisone
• methylprednisolone

what is used PRN to prevent chronic asthma

beclomethasone

side effects of beclomethasone

oropharyngeal candidasis, hoarseness

glucocorticoid/long acting beta2-andrenergic agonist combinations

1. flumicasone/salmeterol
2. budesonide/formoterol
3. mometasone/formoterol

leukotriene modifer prototype drug

montelukast

montelukast is a ____

second line therapy drug

route for montelukast is

PO

how long does montelukast take to start its effects

2 weeks

montelukast BBW

neuropsychiatric effects

prototype drug of immunosuppressant monoclonal antibodies

omalizumab

What do we use for severe allergic asthma

omalizumab!

what does omalizumab do?

inhibits IgE bindingto mast and basophils, reducing allergic response

omalizumab BBW

anaphylaxis after first dose and after 1 year of using it

prototype drug of mast cell stabilizer

cromolyn sodium

when do we use cromolyn sodium

if the pt is allergic to glucocorticoid steroids

is cromolyn sodium good for acute attacks or for prophylaxis?

PROPHYLAXIS