Pathophysiology Week 1 Quiz
Which statement accurately describes the proliferation of cancer cells?
The number of developing cells exceeds the number of dying cells
A critical event in the death of a cell is caused by
Disruption of the plasma membranes permeability barrier
A client develops weakness in both lower extremities following a prolonged period of bed rest. This condition is most likely caused by
Atrophy
Which of these statements best describes the purpose of the TNM classification system?
It provides tumor data for the Centers for Disease Control and Prevention.
Which gene has been identified as specifically contributing to some types of breast cancer?
BRCA1
An increase in which of these characteristics would be present in cells that demonstrate hypertrophy?
Size of cells
Abnormal new cellular growth is referred to as
Neoplasia
Which condition explains the genetic basis for cancer development?
Loss of or defect in tumor suppressor genes
Necrosis is the result of cellular injury that does not allow for cellular adaptation because it is which of the following? (Select all that apply.)
Too severe
Too prolonged
Which term is used to describe the deficiency in circulating platelets?
Thrombocytopenia
Which term means cause of the disease?
Etiology
In muscle hypertrophy, the hypertrophied cells increase in
Size
Which is true regarding catecholamines?
They include epinephrine and norepinephrine
Which is a characteristic of cancer cells?
Poor differentiation
Which cellular response is maladaptive?
Change in the shape or arrangement of cells
A heart that has to pump harder in order to effectively circulate blood is likely to undergo which type of cellular adaptation?
Hypertrophy
Which hormone is responsible for lactation and interferes with ovulation?
Prolactin
Cellular hypoxia results in
Failure of the sodium-potassium pump
Signs and symptoms of a disease first occur during the
Prodromal
What stage is defined by “fight or flight”?
Alarm
Which offers the best prognosis for the cure of cancer?
Early detection
A critical event in the death of a cell is caused by
Disruption of the plasma membrane s permeability barrier
Which statement is true regarding cancer? (Select all that apply.)
The greater the undifferentiated cell count, the more aggressive the cancer.
Malignant tumors have the potential to kill the host.
Which term is used to describe the histologic characterization of tumor cells?
Grading
Which condition occurs in the presence of cellular damage?
Sodium and water move into the cell.
In what way do proto-oncogenes become activated oncogenes?
Certain retroviruses enter host cells, altering their DNA structure.
Which condition explains the genetic basis for cancer development?
Loss of or defect in tumor suppressor genes
Restoration of effective function is the goal of which level of prevention?
Tertiary
A disease that is native to a particular region
Endemic
Apoptosis is a process that results in cellular
death
Your patient eats "lots of fat," leads a "stressful" life, and has smoked "about two packs a day for the last 40 years." Her chronic morning cough recently worsened, and she was diagnosed with a lung mass. The most likely contributing factor for development of lung cancer in this patient is
cigarette smoking
Cancer grading is based on
cell differentiation
Allostasis is best defined as
the overall process of adaptive change necessary to maintain survival and well- being
A patient with high blood pressure who is otherwise healthy is counseled to restrict sodium intake. This is an example of?
secondary prevention
After bronchoscopy and histologic examination of a suspected tumor, G.P. is diagnosed with primary bronchial carcinoma. Thus, the tumor is?
malignant
After suffering a heart attack, a middle-aged man is counseled to take a cholesterol-lowering medication. This is an example of?
tertiary prevention
Which of the following normally is not secreted in response to stress?
insulin
C.Q. was recently exposed to group A
hemolytic Streptococcus and
subsequently developed a pharyngeal infection. His clinic examination
reveals an oral temperature of 102.3° F, skin rash, dysphagia, and
reddened throat mucosa with multiple pustules. He complains of sore
throat, malaise, and joint stiffness. A throat culture is
positive
for Streptococcus, and antibiotics have been prescribed.
The etiology of C.Q.'s disease is
streptococcal infection
Your patient is scheduled for a staging procedure. She wants to know what that means. Which response is correct?
It is a procedure for determining the extent of tumor spread
Many of the responses to stress are attributed to activation of the sympathetic nervous system and are mediated by?
norepinephrine
Metaplasia
the replacement of one differentiated cell type with another
The cellular response indicative of injury due to faulty metabolism
intracellular accumulations
Side effect of chemotherapy include
need to answer?
Selye's three phases of the stress response include all the following
Alarm
Resistance
Exhaustion
The stage during which the patient functions normally, although the disease process are well established, is referred to as?
Subclinical