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ap exam 3 - urinary system

front 1

The kidney is referred to as an excretory organ because it excretes nitrogenous wastes.

back 1

no data

front 2

It is also a major homeostatic organ because it maintains the electrolyte, fluid and acid-base balance of the blood.

back 2

no data

front 3

Urine is continuously formed by the kidneys and is routed down the ureters by the mechanism of peristalsis to a storage organ called the bladder

back 3

no data

front 4

Eventually, the urine is conducted to the body exterior by the urethra.

back 4

no data

front 5

In the male, the urethra is 20 centimeters long and transports both urine and sperm

back 5

no data

front 6


The female urethra is 4 centimeters long and transports only urine.

back 6

no data

front 7


Voiding or emptying the bladder is called micturation

back 7

no data

front 8

Voiding has both voluntary and involuntary components.

The voluntary sphincter is the external sphincter.

back 8

no data

front 9

An inability to control this sphincter is referred to as incontinence

back 9

no data

front 10

Hypertonic

back 10

the concentration of solutes is greater outside the cell than inside it

** high solute

front 11

Hypotonic

back 11

the concentration of solutes is greater inside the cell than outside of it

** low solute

front 12


Isotonic

back 12

the concentration of solutes is the same both inside and outside of the cell

front 13

Osmoregulation

back 13

The process of regulating water potential in order to keep fluid and electrolyte balance within a cell or organism relative to the surrounding

front 14

Osmolarity

back 14

The osmotic concentration of a solution expressed as osmoles of solute per liter of solution.

*** affected by solute

More solute more osmotic pressure

Less solute less osmotic pressure

front 15

Excess potassium ion is eliminated from the body by?

back 15

Tubular secretion

front 16

In the presence of ADH (anti diuretic hormone) one would produce concentrated or diluted urine?

back 16

more concentrated

front 17

Bowman's capsule and the glomerulus make up the?

back 17

renal corpuscle

front 18

Why is incontinence a normal phenomenon in the child under 11⁄2 to 2 years old?

back 18

Because they have not yet gained muscle control over their external spincter

front 19

What events may lead to its occurrence in the adult?

back 19

-Spinal cord injury

-emotional problems

-bladder irritability

-or some other pathology of the urinary tract

front 20

smooth membrane, tightly adherent to the kidney surface on

back 20

fibrous capsule

front 21

portion of the kidney containing mostly collecting ducts

back 21

medulla

front 22

portion of the kidney containing the bulk of the nephron structures

back 22

cortex

front 23

superficial region of kidney tissue

back 23

cortex

front 24

basinlike area of the kidney, continuous with the ureter

back 24

renal pelvis

front 25

a cup-shaped extension of the pelvis that encircles the apex of a pyramid

back 25

minor calyx

front 26

area of cortical tissue running between the medullary pyramids

back 26

renal column

front 27

site of filtrate formation

back 27

glomerulus

front 28

primary site of tubular reabsorption

back 28

proximal convoluted tubule

front 29

secondarily important site of tubular reabsorption

back 29

distal convoluted tubule

front 30

structure that conveys the processed filtrate (urine) to the renal pelvis

back 30

distal convoluted tubule

front 31

blood supply that directly receives substances from the tubular cells

back 31

peritubular capillaries

front 32

its inner (visceral) membrane forms part of the filtration membrane

back 32

glomerular capsule

front 33

In vertebrates (humans) where is urea produced?

back 33

-liver from NH3 and CO2

front 34

Urea is produced when ammonia (NH 3 ) is combined with……?

back 34

CO2

front 35

How does its high-pressure condition in the glomerulus aid its function of filtrate formation?

back 35

The higher the capillary pressure, the more filtrate will be formed.

front 36

The basic functional unit of the kidney is the?

back 36

nephron

front 37

Compare and contrast the composition of blood plasma and glomerular filtrate?

back 37

-B lood plasma → contains red and white blood cells, blood proteins, glucose, water, nitrogenous waste and salts.

-Glomerular filtrate → contains everything blood plasma does without most of the blood proteins

front 38

Explain the mechanism of tubular secretion, and explain its importance in the urine formation process?

back 38

- Tubular secretion is the reverse process of tubular reabsorption. Substances such as hydrogen and potassium ions and creatinine move either from the blood of the peritubular capillaries through the tubular cells or from the tubular cells into the filtrate to be disposed of in the urine. This process is important for the disposal of substances not ready in the filtrate and as a device for controlling blood pH

front 39

Compare and contrast the composition of blood plasma and glomerular filtrate?

back 39

B lood plasma → contains red and white blood cells, blood proteins, glucose, water, nitrogenous waste and salts.

-Glomerular filtrate → contains everything blood plasma does without most of the blood proteins

front 40

The outermost layer of kidney tissue is the?

back 40

-Renal cortex

front 41

List components of urine from a healthy person?

back 41

-Healthy urine consists of water, ammonia, potassium, hydrogen, little sodium, little creatine, little uric acid and urea and little bilirubin, if any of these substance is present in too much (or to little) quanity then it becomes unhealthy. Substances not normally in urine-glucose, protein, RBC, WBC and hemoglobin.

front 42

Trace a drop of blood from the time it enters the kidney via the renal artery until it leaves the kidney through the renal vein.

back 42

Renal Artery to segmental artery lobar artery interlobar artery arcuate artery interlobular artery afferent arteriole glomerulus efferent arteriole peritubular capillary bed interlobular vein arcuate vein interlobar vein

front 43

In response to a drop in overall blood pressure, ___ stimulates constriction of the glomerular inlet and even greater constriction of the outlet?

back 43

angiotensin II

front 44

The process of urine formation involves…?

back 44

- filtration of the plasma, reabsorption from the filtrate, and the secretion into the filtrate

front 45

What is important functionally about the specialized epithelium (transitional epithelium) in the bladder?

back 45

- The cells can slide past one another giving the tissue the ability to stretch and recoil as the bladder fills and empties

front 46

Atrial natriuretic peptide reduces blood volume and pressure by?

back 46

- Increasing glomerular filtration rate

-Inhibiting rennin and aldosterone secretion

-Inhibiting the action of ADH on the kidney

-Inhibiting NaCl reabsorption by the collecting duct

front 47

An interplay between calcium reserves in the bone, the rate of absorption, and the rate of excretion reflects calcium homeostasis. Explain this?

back 47

no data

front 48

Calcium reabsorption by the kidneys is promoted by the hormone?

back 48

parathyroid hormone

front 49

Trace the anatomical pathway of a molecule of creatinine (metabolic waste) from the glomerular capsule to the urethra. Note each microscopic and/or gross structure it passes through in its travels. Name the subdivisions of the renal tubule.

back 49

Glomerular Capsule → Proximal Convulated Tubule → Loop of Henle → Distal Convulated Tubule → Collecting Tubule → Papillary Duct → Minor Calyx → Renal Pelvis → Ureter → Bladder → Urethra

front 50

Explain why urinalysis is a routine part of any good physical examination?

back 50

Finding "abnormal" constituents in the urine may indicate pathology

front 51

Presence of glucose in the urine is indication of…?

back 51

- Glycosuria

- causes could be excess carbohydrate intake of diabetes mellitus

front 52

Substances larger than ________ are normally not allowed to pass through the filtration membrane?

back 52

albumin

front 53

In the presence of ADH (anti diuretic hormone)urine production increases or decreases?

back 53

*** decreases

front 54

Which has a greater specific gravity: 1 ml of urine or 1 ml of distilled water?

Explain your answer why?

back 54

- URINE; BECAUSE IT CONTAINS DISSOLVED SOLUTES, WHICH ARE NOT FOUND IN DISTILLED WATER AND ADD TO THE DENSITY OF THE SAMPLE

front 55

How does a urinary tract infection influence urine pH?

back 55

alkaline

front 56

Urine is carried to the urinary bladder by?

back 56

the ureters

front 57

Name the primary nitrogenous waste product in humans?

back 57

Urea

front 58

Glucose and albumin are both normally absent in the urine, but the reason for their exclusion differs.

Explain the reason for the absence of glucose?

Explain the reason for the absence of albumin?

back 58

no data

front 59

Name the three major nitrogenous wastes found in the urine?

back 59

Uric acid

-Urea

-creatine

front 60

List functions of the kidneys?

back 60

-They filter blood plasma

-They regulate blood volume and pressure by eliminating or conserving water

-They regulate the osmolarity of the body fluids by controlling the relative amounts of water and solutes

-They secrete rennin

-They secrete erythropoietin

-They collaborate with the lungs to regulate the concentration of CO2 and the acid–base balance

-They carry out the final step in synthesizing calcitriol and thereby contribute to calcium homeostasis

front 61

The blood-filtering structure of the kidney is called the?

back 61

Glomerulus

front 62

The primary function of the proximal convoluted tubule is?

back 62

-absorption of ions

-organic molecules

-Vitamins

-water

front 63

Why is glucose in the urine an indicator of diabetes mellitus?

back 63

-when blood glucose is very high, the filtered glucose occupies all the transport carriers and it is no longer reabsorbed

front 64

Nitrogenous waste product is a by product of….?

back 64

Protein metabolism

front 65

The expanded end of the ureter forms the?

back 65

-renal pelvis

front 66

The innermost layer of kidney tissue is the?

back 66

-renal medulla

front 67

Tubular reabsorption involves what kind of transportation?

back 67

- active transport

-facilitated diffusion

-cotransport

-countertransport

front 68

What type of response by the afferent arterioles would you expect if blood pressure increased?

back 68

The afferent arterioles would constrict

front 69

A glomerulus is?

back 69

-the network of capillaries found inside the corpuscle

front 70

The urine-forming units of the kidney are the?

back 70

- nephrons

front 71

What is Gout?

back 71

a common type of arthritis

front 72

What leads to Gout i.e. what is the cause of Gout?

back 72

-Gout is caused by a build-up of uric acid in the body. Uric acid is a waste product that is produced during the process of metabolism (when the body breaks down food to use as energy).

front 73

Byproduct of protein catabolism that constitutes approximately one-half of all nitrogenous waste is…..?

back 73

-urea

front 74

The function of calcitonin is to?

back 74

Decreases Blood Calcium by causing Ca to move from blood into bone

front 75

What would be the effect on urine output if sodium channels in the tubule cells were inhibited?

back 75

The volume would increase

front 76

All urine specimens become alkaline and cloudy on standing at room temperature. Explain why?

back 76

-This is a result of bacterial metabolism of urinary components

front 77

Explain the mechanism of tubular secretion, and explain its importance in the urine formation process?

back 77

- Tubular secretion is the reverse process of tubular reabsorption. Substances such as hydrogen and potassium ions and creatinine move either from the blood of the peritubular capillaries through the tubular cells or from the tubular cells into the filtrate to be disposed of in the urine. This process is important for the disposal of substances not ready in the filtrate and as a device for controlling blood pH

front 78

A renal pyramid voids urine into?

back 78

the minor calyx

front 79

The process of filtration occurs at?

back 79

corpuscle of nephron

front 80

Which of the following processes in urine formation is important for regulating blood pH: Filtration; Secretion; reabsorption? Why?

back 80

-Secretion

front 81

The functional unit of kidney is called what?

back 81

-nephron

front 82

What is the advantage of excreting nitrogenous wastes as urea rather than as ammonia?

back 82

-urea is less toxic than ammonia

front 83

List factors that contribute(s) to the higher filtration rate in the glomerular capillaries compared with other capillary beds?

back 83

  1. glomerular capillaries are fenestrated
  2. the diameter of the efferent arteriole is smaller than the diameter of the afferent arteriole
  3. the visceral layer of the glomerular capsule is very porous

front 84

How would eating a high-protein diet affect filtration?

back 84

Due to higher colloid osmotic pressure in the glomerular blood, the net filtration pressure would be lower and less filtrate would form

front 85

Blood plasma is filtered in which portion of the nephron?

back 85

- renal corpuscle

front 86

How urinary system does regulate body pH?

back 86

no data

front 87

List substances that are found in plasma but would not be found in normal filtrate?

back 87

proteins

front 88

The portion of the nephron closest to the renal corpuscle is the?

back 88

-proximal convoluted tubule

front 89

Drinking too much alcohol results in a headache the next day. Why does this happen?

back 89

-Alcohol inhibits ADH secretion

front 90

Conical-shaped structures that are located in the renal medulla are called?

back 90

-pyramids

front 91

What is the function of reabsorption?

back 91

no data

front 92

Materials are returned to the blood from the filtrate by…… process?

back 92

-selective reabsorption

front 93

Substances and molecules move out of capillaries into the corpuscle space due to….?

back 93

-pressure differences

front 94

The transfer of fluid from the glomerulus to Bowman's capsule (corpuscle space) is mainly due high pressure in the……?

back 94

glomerulus capillaries

front 95

Why is the osmolarity of medullary fluid in the kidney almost four times higher than the osmolarity of plasma?

back 95

- loop of Henle acts as a countercurrent multiplier and contributes solutes to the interstitial fluid & urea is recycled from the collecting duct and is transported to the interstitial fluid

** anatomical structure of loop of Henle

front 96

  1. Glucose and amino acids are reabsorbed from the glomerular filtrate by the….convoluted tubule?

back 96

the proximal convoluted tubule

front 97

How does ADH contribute to the formation of concentrated urine?

back 97

-ADH increases the permeability of the collecting duct to water by stimulating the insertion of aquaporins into the luminal membrane

front 98

When stimulated by aldosterone, the reabsorption of Na+ is increased along which tubule of nephron?

back 98

-the distal tubule

front 99

Increased ADH secretion is most likely when…….?

back 99

-sweating-induced dehydration increases plasma osmolarity

front 100

Why human urine more acidic is i.e. what makes it acidic?

back 100

Presence of hydrogen ions

front 101

What is the advantage of urine being acidic?

back 101

To act as a nonspecific defense

front 102

Why the kidneys have one of the highest metabolic rates of all body organs?

back 102

-it operates an extensive set of active-transport ion pumps

front 103

Alcoholic beverages, increased urine excretion because….?

back 103

-inhibited secretion of antidiuretic hormone (ADH)

front 104

What role do the vasa recta play in urine formation?

back 104

-it removes solutes and water

-balances solute reabsorption and osmosis in the medulla

front 105

The portion of the nephron that attaches to the collecting duct is the?

back 105

-distal convoluted tubule

front 106

When considering drug administration, why is it important to know the renal clearance rate of the drug?

back 106

-It dictates the dosage and frequency of administration of drugs

front 107

Suppose 3 friends decide to an experiment on themselves. One person drinks 1 liter water, a second person drinks 1 liter of beer, and a third drinks 1 liter of concentrated salt solution. They monitor their urine production for several hours. Explain who will you expect to have the greatest and who will you expect to have the least amounts of urine, respectively? Explain why?

back 107

beer- most urine

salt - less urine

front 108

The process of voiding the bladder is called?

back 108

micturition

front 109

Antidiuretic hormone (ADH) functions at the cellular level by causing an increase in the number of…..?

back 109

- aquaporin molecules of collecting duct cells

front 110

The largest solute component of urine…….?

back 110

-Urea

front 111

Urine is produced by which organ of urinary system?

back 111

kidneys

front 112

A patient feels radiating pain from the side of her body to the anterior abdominal wall. An MRI shows a bulging renal pelvis. Which is the most likely cause?

back 112

-A kidney stone lodged in the ureter

front 113

What features of the bladder predispose it to being able to stretch and relax repeatedly?

back 113

- the walls are highly folded into rugae and the epithelium is transitional

front 114

What is the functional difference between a male urethra and a female urethra?

back 114

no data

front 115

The “U” shape structure of the nephron tubules is called?

back 115

no data

front 116

Micturition is another term for?

back 116

the elimination of urine

front 117

Aldosterone promotes ……..retention in the kidneys?

back 117

sodium retention

front 118

Explain why the glomerulus is such a high-pressure capillary bed?

back 118

-Both fed and drained by arterioles; the afferent arterioles has a larger diameter than the efferent

front 119

How does its high-pressure condition aid its function of filtrate formation?

back 119

-the higher the capillary pressure, the more filtrate will be formed