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Activity 2: Studying the Microscopic Anatomy of a Lymph node, the Spleen, and a Tonsil

front 1

The lymph node is enclosed in what?

back 1

A fibrous capsule

front 2

From the fibrous capsule of the lymph node, what extends inwards to divide the node into several compartments?

back 2

Trabeculae

front 3

The trabeculae is composed of what tissue type?

back 3

Connective tissue

front 4

The cortex contains what type of center?

back 4

Germinal center

front 5

The germinal centers contain what rapidly-dividing group of cells?

back 5

B lymphocytes/cells

front 6

The rest of the cortical cells (cortex cells) are primarily what group of cells?

back 6

T cells

front 7

The remaining T lymphocytes/cells in the cortical or cortex cells do what in regard to circulation?

back 7

Circulate continuously from the blood into the nodes, and then from exiting the nodes in the lymphatic stream

front 8

Lymphocytes are arranged in a cordlike fashion in what portion of the lymph nodes?

back 8

Medulla portion

front 9

Most medullary cells are what type of cells?

back 9

Macrophages

front 10

Macrophages are important for what 2 functions?

back 10

1. Phagocytosis

2. Antigen-presentation to the T cells

front 11

Lymph enters the lymph nodes through what vessels?

back 11

Afferent vessels

front 12

Lymph circulates through what in the lymph nodes?

back 12

Lymph sinuses

front 13

Lymph leaves the lymph nodes through what vessels located at which structure of the nodes?

back 13

Leaves through efferent vessels at the hilum

front 14

What is the benefit of having fewer efferent vessels than afferent vessels?

back 14

The lymph stagnates within the node

front 15

Why is it beneficial to have lymph stagnate within the nodes? (Hint: 2 reasons)

back 15

1. Allows time to generate an immune response

2. Allows macrophages to remove debris from the lymph before it reenters the blood vascular system

front 16

In the spleen, the white pulp are areas of what cells suspended in what fibers?

back 16

Areas of lymphocytes suspended in reticular fibers

front 17

The white pulp is clustered around what vessels?

back 17

Central arteries

front 18

The red pulp of the spleen has what 3 components? (Hint: sinusoids, tissue, cell type)

back 18

1. Splenic sinusoids

2. Reticular tissue

3. Macrophages

front 19

The macrophages in the red pulp are called what?

back 19

Splenic cords

front 20

Which pulp is responsible for the immune functions of the spleen?

back 20

White pulp

front 21

Why is the white pulp responsible for the immune functions of the spleen?

back 21

It contains primarily lymphocytes

front 22

Macrophages in the red pulp remove what 5 substances?

back 22

1. Worn-out RBCs

2. Debris

3. Bacteria

4. Viruses

5. Toxins

front 23

In tonsils, what contains the germinal centers?

back 23

Lymphoid follicles

front 24

The lymphoid follicles and germinal centers are surrounded by what cell type?

back 24

Lymphocytes

front 25

What is the function of the tonsilar crypts of the tonsils?

back 25

Trap bacteria and other foreign material.

front 26

How are bacteria in the tonsils destroyed eventually?

back 26

Eventually, they work their way into the lymphoid tissue and are destroyed.

front 27

Identify the blanks.

back 27

front 28

Identify the blanks.

back 28

front 29

Identify the blanks.

back 29

front 30

Identify the blanks.

back 30

front 31

Identify the blanks.

back 31

front 32

1. Identify the blanks.

2. What lymphoid organ is this slide?

back 32

2. Lymph node

front 33

1. Identify the blanks.

2. What lymphoid organ is this slide?

back 33

2.Tonsil

front 34

1. Identify the blanks.

2. What lymphoid organ is this slide?

back 34

2. Spleen