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Genetics Chapter 4

front 1

With incomplete dominance, a likely ratio resulting from a monohybrid cross would be ________.
A) 3:3
B) 1:2:2:4
C) 1:2:1
D) 9:3:3:1
E) 3:1

back 1

C) 1:2:1

front 2

A situation in which there are more than two alternative forms of a given gene would be called ________.
A) multiple alleles
B) alternation of generations
C) codominance
D) incomplete dominance
E) hemizygosity

back 2

A) multiple alleles

front 3

A condition in which one gene pair masks the expression of a nonallelic gene pair is called ________.
A) codominance
B) epistasis
C) dominance
D) recessiveness
E) additive alleles

back 3

B) epistasis

front 4

Typical ratios resulting from epistatic interactions in dihybrid crosses would be ________.
A) 9:3:3:1, 1:2:1
B) 1:1:1:1, 1:4:6:4:1
C) 9:3:4, 9:7
D) 1:2:2:4:1:2:1:2:1
E) 3:1, 1:1

back 4

C) 9:3:4, 9:7

front 5

With which of the following would hemizygosity most likely be associated?
A) codominance
B) incomplete dominance
C) trihybrid crosses
D) X-linked inheritance
E) sex-limited inheritance

back 5

D) X-linked inheritance

front 6

A mutation in a gene often results in a reduction of the product of that gene. The term for this type of mutation is ________.
A) codominance
B) incomplete dominance
C) gain of function
D) multiple allelism
E) loss of function or null (in the case of complete loss)

back 6

E) loss of function or null (in the case of complete loss)

front 7

Because of the mechanism of sex determination, males of many species can be neither homozygous nor heterozygous. Such males are said to be ________.
A) dominant
B) hemizygous
C) recessive
D) complementary
E) None of the answers listed is correct.

back 7

B) hemizygous

front 8

With multiple alleles, there can be more than two genetic alternatives for a given locus.

back 8

TRUE

front 9

With both incomplete dominance and codominance, one expects heterozygous and homozygous classes to be phenotypically identical.

back 9

FALSE

front 10

The ABO blood group locus in humans provides an example of epistasis.

back 10

FALSE

front 11

Sex-limited inheritance is the same as sex-linked inheritance.

back 11

FALSE

front 12

A conditional mutant is one whose expression is influenced by some environmental condition.

back 12

TRUE

front 13

A typical epistatic ratio is 9:3:4.

back 13

TRUE

front 14

A 9:7 ratio indicates incomplete dominance

back 14

FALSE

front 15

Pattern baldness and hen/cock feathering in fowl are examples of X-linked inheritance.

back 15

FALSE

front 16

Penetrance specifically refers to the expression of lethal genes in heterozygotes.

back 16

FALSE

front 17

Expressivity is the term used to describe the balanced genetic output from a hemizygous condition.

back 17

FALSE

front 18

Hemizygosity is the term one uses to describe the state of a gene that has no allele on the opposing chromosome.

back 18

TRUE

front 19

Genomic imprinting occurs when one allele converts another.

back 19

FALSE

front 20

Genomic anticipation refers to observations that a genetic disorder occurs at an earlier age in successive generations, whereas genetic imprinting occurs when gene expression varies depending on parental origin.

back 20

TRUE

front 21

"Gain of function" mutations are generally dominant since one copy in a diploid organism is sufficient to alter the normal phenotype.

back 21

TRUE

front 22

Assume that a mutation occurs in the gene responsible for the production of hexosaminidase A, such that only about 50% of the enzyme activity is found in the heterozygote compared with a homozygous normal individual. If heterozygotes are phenotypically normal, we would say that the mutant allele is recessive to its normal allele.

back 22

TRUE

front 23

Alleles that are masked by an epistatic locus are said to be hypostatic to the genes at that locus.

back 23

TRUE

front 24

One result of X-linkage is a crisscross pattern of inheritance in which sons express recessive genes of their fathers and daughters express recessive genes of their mothers.

back 24

FALSE

front 25

The term expressivity defines the percentage of individuals who show at least some degree of expression of a mutant genotype.

back 25

FALSE