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biology 2 quiz.

front 1

Lipid-soluble signaling molecules, such as testosterone, cross the membranes of all cells but affect only target cells because:

back 1

Intracellular receptors are present only in target cells.

front 2

GTPase activity is involved in the regulation of signal transduction because it:

back 2

Hydrolyzes GTP binding to G protein.

front 3

Match the key event of meiosis with the stages listed below. Tetrads of chromosomes are aligned at the equator of the spindle; alignment determines independent assortment.

back 3

B. II

front 4

testosterone functions inside a cell by:

back 4

binding with a receptor protein that enters the nucleus and activates specific genes.

front 5

Match the key event of meiosis with the stages listed below. Centromeres of sister chromatids disjoin and chromatids separate

back 5

A. II

front 6

What is a cleavage furrow?

back 6

A groove in the plasma membrane between daughter nuclei.

front 7

When a neuron responds to a particular neurotransmitter by opening gated ion channels, the neurotransmitter is serving as which part of the signal pathway?

back 7

signal molecule

front 8

What are scaffolding proteins?

back 8

large molecules to which several relay proteins attach to facillitate cascade effects

front 9

The function of phosphatases in signal transduction is best described as to:

back 9

inactivate protein kinases and turn off the signal transduction.

front 10

Which of the following is true concerning cancer cells?

back 10

E) A,B,C

-A) They do not exhibit density-dependent inhibition when growing in culture.
B) When they stop dividing, they do so at random points in the cell cycle.
C) They are not subject to cell cycle controls.

front 11

Consider this pathway: epinephrine → G protein-coupled receptor → G protein → adenylyl cyclase → camp. Identify the second messenger.

back 11

camp.

front 12

In a human karyotype, chromosomes are arranged in 23 pairs. If one of these pairs is chosen, such as pair 14, which of the following do the two chromosomes of the pair have in common?

back 12

Length, centromere position, staining pattern, and traits coded for by their genes.

front 13

Homologous chromosomes move toward opposite poles of a dividing cell during:

back 13

meiosis I

front 14

After which checkpoint is the cell first committed to continue the cell cycle through M?

back 14

G1

front 15

Which of the following occurs in meiosis but not in mitosis?

back 15

synapsis of chromosomes.

front 16

Why do neurons and some other specialized cells divide infrequently?

back 16

They have been shunted into g0

front 17

The human X and Y chromosomes:

back 17

include genes that determine an individual's sex.

front 18

Adenylyl cyclase has the opposite effect of which of the following?

back 18

Phosphodiesterase

front 19

The top circle in Figure 12.1 shows a diploid nucleus with four chromosomes. There are two pairs of homologous chromosomes, one long and the other short. One haploid set is symbolized as black and the other haploid set is gray. The chromosomes in the top circle have not yet replicated
Choose the correct chromosomal condition for prometaphase of mitosis.

back 19

B

front 20

Which of the following is a protein maintained at constant levels throughout the cell cycle that requires cyclin to become catalytically active?

back 20

CDK

front 21

Refer to the drawings of a single pair of homologous chromosomes in Figure 13.2 as they might appear during various stages of either mitosis or meiosis.
Which diagram represents anaphase I of meiosis?

back 21

I

front 22

Which number represents dna synthesis?

back 22

II

front 23

Which of the following does not occur during mitosis?

back 23

replication of the DNA

front 24

A human cell containing 22 autosomes and a Y chromosome is:

back 24

a sperm

front 25

Density-dependent inhibition is explained by which of the following?

back 25

As cells become more numerous, the cell surface proteins of one cell contact the adjoining cells and they stop dividing.

front 26

Which of the following most accurately describes a cyclin?

back 26

It activates a CDK molecule when it is in sufficient concentration.

front 27

Why do chromosomes coil during mitosis?

back 27

to allow the chromosomes to move without becoming entangled and breaking

front 28

In the figure above, mitosis is represented by which numbered part(s) of the cycle?

back 28

IV

front 29

Which of the following is the best explanation for the fact that most transduction pathways have multiple steps?

back 29

Multiple steps provide for greater possible amplification of a signal.

front 30

For anaphase to begin, which of the following must occur?

back 30

Cohesin must be cleaved enzymatically.

front 31

Which of the following defines a genome?

back 31

The complete set of an organism's genes.

front 32

Independent assortment of chromosomes occurs.

back 32

The statement is true for meiosis I only.

front 33

The activation of receptor tyrosine kinases is characterized by:

back 33

Dimerization and phosphorylation.

front 34

Which of the following happens at the conclusion of meiosis I?

back 34

Homologous chromosomes are separated.

front 35

Where do the microtubules of the spindle originate during mitosis in both plant and animal cells?

back 35

centrosome

front 36

Measurements of the amount of DNA per nucleus were taken on a large number of cells from a growing fungus. The measured DNA levels ranged from 3 to 6 picograms per nucleus. In which stage of the cell cycle did the nucleus contain 6 picograms of DNA?

back 36

G2

front 37

After telophase I of meiosis, the chromosomal makeup of each daughter cell is:

back 37

haploid, and the chromosomes are each composed of two chromatids.

front 38

In the figure, the dots in the space between the two structures represent which of the following?

back 38

neurotransmitters

front 39

The centromere is a region in which:

back 39

Chromatids remain attached to one another until anaphase.

front 40

One of the major categories of receptors in the plasma membrane reacts by forming dimers, adding phosphate groups, and then activating relay proteins. Which type does this?

back 40

Receptor tyrosine kinases

front 41

A chemical reaction that has a positive ΔG is correctly described as:

back 41

endergonic

front 42

Which of the following is true for all exergonic reactions?

back 42

The reaction proceeds with a net release of free energy.

front 43

Which of the following is (are) true for anabolic pathways?

back 43

They consume energy to build up polymers from monomers.

front 44

Which temperature and pH profile curves on the graphs were most likely generated from analysis of an enzyme from a human stomach where conditions are strongly acid?

back 44

Curves 1 and 4

front 45

Reactants capable of interacting to form products in a chemical reaction must first overcome a thermodynamic barrier known as the reaction's:

back 45

Activation energy

front 46

Which of the following statements describes NAD+?

back 46

NAD+ is reduced to NADH during glycolysis, pyruvate oxidation, and the citric acid cycle.

front 47

The ATP made during glycolysis is generated by:

back 47

Substrate-level phosphorylation.

front 48

Which of the following statements describes the results of this reaction?
C6H12O6 + 6 O2 → 6 CO2 + 6 H2O + Energy

back 48

C6H12O6 is oxidized and O2 is reduced.

front 49

Starting with one molecule of isocitrate and ending with fumarate, how many ATP molecules can be made through substrate-level phosphorylation (see Figure 9.2)?

back 49

1

front 50

Which of the following is an example of potential rather than kinetic energy?

back 50

A molecule of glucose.

front 51

When skeletal muscle cells undergo anaerobic respiration, they become fatigued and painful. This is now known to be caused by:

back 51

Buildup of lactate.

front 52

Why is glycolysis described as having an investment phase and a payoff phase?

back 52

It uses stored ATP and then forms a net increase in ATP.

front 53

Which curves on the graphs may represent the temperature and pH profiles of an enzyme taken from a bacterium that lives in a mildly alkaline hot springs at temperatures of 70°C or higher?

back 53

Curves 3 and 5

front 54

Phosphofructokinase is an allosteric enzyme that catalyzes the conversion of fructose 6-phosphate to fructose 1,6-bisphosphate, an early step of glycolysis. In the presence of oxygen, an increase in the amount of ATP in a cell would be expected to:

back 54

Inhibit the enzyme and thus slow the rates of glycolysis and the citric acid cycle.

front 55

When you have a severe fever, what grave consequence may occur if the fever is not controlled?

back 55

Change in the tertiary structure of your enzymes.

front 56

For living organisms, which of the following is an important consequence of the first law of thermodynamics?

back 56

The organism ultimately must obtain all of the necessary energy for life from its environment.

front 57

Which of the following statements is representative of the second law of thermodynamics?

back 57

Cells require a constant input of energy to maintain their high level of organization.

front 58

What is the term for metabolic pathways that release stored energy by breaking down complex molecules?

back 58

Catabolic pathways

front 59

In glycolysis, for each molecule of glucose oxidized to pyruvate:

back 59

Two molecules of ATP are used and four molecules of ATP are produced.

front 60

Which of the following produces the most ATP when glucose (C6H12O6) is completely oxidized to carbon dioxide (CO2) and water?

back 60

Oxidative phosphorylation (chemiosmosis)

front 61

The following question is based on the reaction A + B ↔ C + D shown in Figure 8.1.
Which of the following represents the activation energy required for the enzyme-catalyzed reaction in Figure 8.1?

back 61

B

front 62

An electron loses potential energy when it:

back 62

Shifts to a more electronegative atom.

front 63

Figure 9.1 illustrates some of the steps (reactions) of glycolysis in their proper sequence. Each step is lettered. Use these letters to answer the questions 47-49.
In which step in Figure 9.1 is an inorganic phosphate added to the reactant?

back 63

C

front 64

Where does glycolysis take place in eukaryotic cells?

back 64

Cytosol

front 65

Which of the following is a statement of the first law of thermodynamics?

back 65

Energy cannot be created or destroyed.

front 66

The molecule that functions as the reducing agent (electron donor) in a redox or oxidation-reduction reaction:

back 66

Loses electrons and loses potential energy.

front 67

Where are the proteins of the electron transport chain located?

back 67

Mitochondrial inner membrane

front 68

Which of the following statements is true concerning catabolic pathways?

back 68

They supply energy, primarily in the form of ATP, for the cell's work.

front 69

Why is ATP an important molecule in metabolism?

back 69

It provides energy coupling between exergonic and endergonic reactions.

front 70

Figure 9.1 illustrates some of the steps (reactions) of glycolysis in their proper sequence. Each step is lettered. Use these letters to answer the questions 47-49.
Which step in Figure 9.1 shows a split of one molecule into two smaller molecules?

back 70

B

front 71

Which of the following intermediary metabolites enters the citric acid cycle and is formed, in part, by the removal of a carbon (CO2) from one molecule of pyruvate?

back 71

Acetyl coa

front 72

According to the induced fit hypothesis of enzyme catalysis, which of the following is correct?

back 72

The binding of the substrate changes the shape of the enzyme's active site.

front 73

The active site of an enzyme is the region that:

back 73

Is involved in the catalytic reaction of the enzyme.

front 74

Energy released by the electron transport chain is used to pump H+ into which location in eukaryotic cells?

back 74

Mitochondrial intermembrane space

front 75

Figure 9.1 illustrates some of the steps (reactions) of glycolysis in their proper sequence. Each step is lettered. Use these letters to answer the questions 47-49.
Which portion of the pathway in Figure 9.1 contains a phosphorylation reaction in which ATP is the phosphate source?

back 75

A

front 76

Which of the following occurs in the cytosol of a eukaryotic cell?

back 76

Glycolysis and fermentation

front 77

In cellular respiration, the energy for most ATP synthesis is supplied by:

back 77

A proton gradient across a membrane.

front 78

Where is ATP synthase located in the mitochondrion?

back 78

Inner membrane

front 79

The primary role of oxygen in cellular respiration is to:

back 79

Act as an acceptor for electrons and hydrogen, forming water.

front 80

Which process in eukaryotic cells will proceed normally whether oxygen (O2) is present or absent?

back 80

Glycolysis