front 1 Lipid-soluble signaling molecules, such as testosterone, cross the membranes of all cells but affect only target cells because: | back 1 Intracellular receptors are present only in target cells. |
front 2 GTPase activity is involved in the regulation of signal transduction because it: | back 2 Hydrolyzes GTP binding to G protein. |
front 3 Match the key event of meiosis with the stages listed below. Tetrads of chromosomes are aligned at the equator of the spindle; alignment determines independent assortment. | back 3 B. II |
front 4 testosterone functions inside a cell by: | back 4 binding with a receptor protein that enters the nucleus and activates specific genes. |
front 5 Match the key event of meiosis with the stages listed below. Centromeres of sister chromatids disjoin and chromatids separate | back 5 A. II |
front 6 What is a cleavage furrow? | back 6 A groove in the plasma membrane between daughter nuclei. |
front 7 When a neuron responds to a particular neurotransmitter by opening gated ion channels, the neurotransmitter is serving as which part of the signal pathway? | back 7 signal molecule |
front 8 What are scaffolding proteins? | back 8 large molecules to which several relay proteins attach to facillitate cascade effects |
front 9 The function of phosphatases in signal transduction is best described as to: | back 9 inactivate protein kinases and turn off the signal transduction. |
front 10 Which of the following is true concerning cancer cells? | back 10 E) A,B,C
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front 11 Consider this pathway: epinephrine → G protein-coupled receptor → G protein → adenylyl cyclase → camp. Identify the second messenger. | back 11 camp. |
front 12 In a human karyotype, chromosomes are arranged in 23 pairs. If one of these pairs is chosen, such as pair 14, which of the following do the two chromosomes of the pair have in common? | back 12 Length, centromere position, staining pattern, and traits coded for by their genes. |
front 13 Homologous chromosomes move toward opposite poles of a dividing cell during: | back 13 meiosis I |
front 14 After which checkpoint is the cell first committed to continue the cell cycle through M? | back 14 G1 |
front 15 Which of the following occurs in meiosis but not in mitosis? | back 15 synapsis of chromosomes. |
front 16 Why do neurons and some other specialized cells divide infrequently? | back 16 They have been shunted into g0 |
front 17 The human X and Y chromosomes: | back 17 include genes that determine an individual's sex. |
front 18 Adenylyl cyclase has the opposite effect of which of the following? | back 18 Phosphodiesterase |
front 19 The top circle in Figure 12.1 shows a diploid nucleus with four chromosomes. There are two pairs of homologous chromosomes, one long and the other short. One haploid set is symbolized as black and the other haploid set is gray. The chromosomes in the top circle have not yet replicated
| back 19 B |
front 20 Which of the following is a protein maintained at constant levels throughout the cell cycle that requires cyclin to become catalytically active? | back 20 CDK |
front 21 Refer to the drawings of a single pair of homologous chromosomes in Figure 13.2 as they might appear during various stages of either mitosis or meiosis.
| back 21 I |
front 22 Which number represents dna synthesis? | back 22 II |
front 23 Which of the following does not occur during mitosis? | back 23 replication of the DNA |
front 24 A human cell containing 22 autosomes and a Y chromosome is: | back 24 a sperm |
front 25 Density-dependent inhibition is explained by which of the following? | back 25 As cells become more numerous, the cell surface proteins of one cell contact the adjoining cells and they stop dividing. |
front 26 Which of the following most accurately describes a cyclin? | back 26 It activates a CDK molecule when it is in sufficient concentration. |
front 27 Why do chromosomes coil during mitosis? | back 27 to allow the chromosomes to move without becoming entangled and breaking |
front 28 In the figure above, mitosis is represented by which numbered part(s) of the cycle? | back 28 IV |
front 29 Which of the following is the best explanation for the fact that most transduction pathways have multiple steps? | back 29 Multiple steps provide for greater possible amplification of a signal. |
front 30 For anaphase to begin, which of the following must occur? | back 30 Cohesin must be cleaved enzymatically. |
front 31 Which of the following defines a genome? | back 31 The complete set of an organism's genes. |
front 32 Independent assortment of chromosomes occurs. | back 32 The statement is true for meiosis I only. |
front 33 The activation of receptor tyrosine kinases is characterized by: | back 33 Dimerization and phosphorylation. |
front 34 Which of the following happens at the conclusion of meiosis I? | back 34 Homologous chromosomes are separated. |
front 35 Where do the microtubules of the spindle originate during mitosis in both plant and animal cells? | back 35 centrosome |
front 36 Measurements of the amount of DNA per nucleus were taken on a large number of cells from a growing fungus. The measured DNA levels ranged from 3 to 6 picograms per nucleus. In which stage of the cell cycle did the nucleus contain 6 picograms of DNA? | back 36 G2 |
front 37 After telophase I of meiosis, the chromosomal makeup of each daughter cell is: | back 37 haploid, and the chromosomes are each composed of two chromatids. |
front 38 In the figure, the dots in the space between the two structures represent which of the following? | back 38 neurotransmitters |
front 39 The centromere is a region in which: | back 39 Chromatids remain attached to one another until anaphase. |
front 40 One of the major categories of receptors in the plasma membrane reacts by forming dimers, adding phosphate groups, and then activating relay proteins. Which type does this? | back 40 Receptor tyrosine kinases |
front 41 A chemical reaction that has a positive ΔG is correctly described as: | back 41 endergonic |
front 42 Which of the following is true for all exergonic reactions? | back 42 The reaction proceeds with a net release of free energy. |
front 43 Which of the following is (are) true for anabolic pathways? | back 43 They consume energy to build up polymers from monomers. |
front 44 Which temperature and pH profile curves on the graphs were most likely generated from analysis of an enzyme from a human stomach where conditions are strongly acid? | back 44 Curves 1 and 4 |
front 45 Reactants capable of interacting to form products in a chemical reaction must first overcome a thermodynamic barrier known as the reaction's: | back 45 Activation energy |
front 46 Which of the following statements describes NAD+? | back 46 NAD+ is reduced to NADH during glycolysis, pyruvate oxidation, and the citric acid cycle. |
front 47 The ATP made during glycolysis is generated by: | back 47 Substrate-level phosphorylation. |
front 48 Which of the following statements describes the results of this reaction?
| back 48 C6H12O6 is oxidized and O2 is reduced. |
front 49 Starting with one molecule of isocitrate and ending with fumarate, how many ATP molecules can be made through substrate-level phosphorylation (see Figure 9.2)? | back 49 1 |
front 50 Which of the following is an example of potential rather than kinetic energy? | back 50 A molecule of glucose. |
front 51 When skeletal muscle cells undergo anaerobic respiration, they become fatigued and painful. This is now known to be caused by: | back 51 Buildup of lactate. |
front 52 Why is glycolysis described as having an investment phase and a payoff phase? | back 52 It uses stored ATP and then forms a net increase in ATP. |
front 53 Which curves on the graphs may represent the temperature and pH profiles of an enzyme taken from a bacterium that lives in a mildly alkaline hot springs at temperatures of 70°C or higher? | back 53 Curves 3 and 5 |
front 54 Phosphofructokinase is an allosteric enzyme that catalyzes the conversion of fructose 6-phosphate to fructose 1,6-bisphosphate, an early step of glycolysis. In the presence of oxygen, an increase in the amount of ATP in a cell would be expected to: | back 54 Inhibit the enzyme and thus slow the rates of glycolysis and the citric acid cycle. |
front 55 When you have a severe fever, what grave consequence may occur if the fever is not controlled? | back 55 Change in the tertiary structure of your enzymes. |
front 56 For living organisms, which of the following is an important consequence of the first law of thermodynamics? | back 56 The organism ultimately must obtain all of the necessary energy for life from its environment. |
front 57 Which of the following statements is representative of the second law of thermodynamics? | back 57 Cells require a constant input of energy to maintain their high level of organization. |
front 58 What is the term for metabolic pathways that release stored energy by breaking down complex molecules? | back 58 Catabolic pathways |
front 59 In glycolysis, for each molecule of glucose oxidized to pyruvate: | back 59 Two molecules of ATP are used and four molecules of ATP are produced. |
front 60 Which of the following produces the most ATP when glucose (C6H12O6) is completely oxidized to carbon dioxide (CO2) and water? | back 60 Oxidative phosphorylation (chemiosmosis) |
front 61 The following question is based on the reaction A + B ↔ C + D shown in Figure 8.1.
| back 61 B |
front 62 An electron loses potential energy when it: | back 62 Shifts to a more electronegative atom. |
front 63 Figure 9.1 illustrates some of the steps (reactions) of glycolysis in their proper sequence. Each step is lettered. Use these letters to answer the questions 47-49.
| back 63 C |
front 64 Where does glycolysis take place in eukaryotic cells? | back 64 Cytosol |
front 65 Which of the following is a statement of the first law of thermodynamics? | back 65 Energy cannot be created or destroyed. |
front 66 The molecule that functions as the reducing agent (electron donor) in a redox or oxidation-reduction reaction: | back 66 Loses electrons and loses potential energy. |
front 67 Where are the proteins of the electron transport chain located? | back 67 Mitochondrial inner membrane |
front 68 Which of the following statements is true concerning catabolic pathways? | back 68 They supply energy, primarily in the form of ATP, for the cell's work. |
front 69 Why is ATP an important molecule in metabolism? | back 69 It provides energy coupling between exergonic and endergonic reactions. |
front 70 Figure 9.1 illustrates some of the steps (reactions) of glycolysis in their proper sequence. Each step is lettered. Use these letters to answer the questions 47-49.
| back 70 B |
front 71 Which of the following intermediary metabolites enters the citric acid cycle and is formed, in part, by the removal of a carbon (CO2) from one molecule of pyruvate? | back 71 Acetyl coa |
front 72 According to the induced fit hypothesis of enzyme catalysis, which of the following is correct? | back 72 The binding of the substrate changes the shape of the enzyme's active site. |
front 73 The active site of an enzyme is the region that: | back 73 Is involved in the catalytic reaction of the enzyme. |
front 74 Energy released by the electron transport chain is used to pump H+ into which location in eukaryotic cells? | back 74 Mitochondrial intermembrane space |
front 75 Figure 9.1 illustrates some of the steps (reactions) of glycolysis in their proper sequence. Each step is lettered. Use these letters to answer the questions 47-49.
| back 75 A |
front 76 Which of the following occurs in the cytosol of a eukaryotic cell? | back 76 Glycolysis and fermentation |
front 77 In cellular respiration, the energy for most ATP synthesis is supplied by: | back 77 A proton gradient across a membrane. |
front 78 Where is ATP synthase located in the mitochondrion? | back 78 Inner membrane |
front 79 The primary role of oxygen in cellular respiration is to: | back 79 Act as an acceptor for electrons and hydrogen, forming water. |
front 80 Which process in eukaryotic cells will proceed normally whether oxygen (O2) is present or absent? | back 80 Glycolysis |