front 1 Which of these enters the citric acid cycle? | back 1 acetyl CoA Acetyl CoA is a reactant in the citric acid cycle. |
front 2 In the citric acid cycle, ATP molecules are produced by | back 2 substrate-level phosphorylation note: substrate-level phosphorylation |
front 3 Which of these is NOT a product of the citric acid cycle? | back 3 acetyl CoA notE: Acetyl CoA enters the citric acid cycle. |
front 4 A glucose molecule is completely broken down to carbon dioxide and water in glycolysis and the citric acid cycle, but together these two processes yield only a few molecules of ATP. What happened to most of the energy that the cell obtains from the oxidation of glucose? | back 4 It is stored in NADH and FADH2 |
front 5 Which statement about the citric acid cycle is correct? | back 5 The last reaction in the citric acid cycle produces a product that is a substrate for the first reaction of the citric acid cycle. |
front 6 In mitochondrial electron transport, what is the direct role of O2? | back 6 to function as the final electron acceptor in the electron transport chain |
front 7 How would anaerobic conditions (when no O2 is present) affect the rate of electron transport and ATP production during oxidative phosphorylation? (Note that you should not consider the effect on ATP synthesis in glycolysis or the citric acid cycle.) | back 7 Both electron transport and ATP synthesis would stop. |
front 8 NADH and FADH2 are both electron carriers that donate their electrons to the electron transport chain. The electrons ultimately reduce O2 to water in the final step of electron transport. However, the amount of ATP made by electrons from an NADH molecule is greater than the amount made by electrons from an FADH2 molecule.
| back 8 Fewer protons are pumped across the inner mitochondrial membrane when FADH2 is the electron donor than when NADH is the electron donor. |
front 9 When the protein gramicidin is integrated into a membrane, an H+ channel forms and the membrane becomes very permeable to protons (H+ ions). If gramicidin is added to an actively respiring muscle cell, how would it affect the rates of electron transport, proton pumping, and ATP synthesis in oxidative phosphorylation? (Assume that gramicidin does not affect the production of NADH and FADH2 during the early stages of cellular respiration.)
| back 9 remains the same: proton pumping rate, electron transport rate, rate of oxygen uptake
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front 10 The four stages of cellular respiration do not function independently. Instead, they are coupled together because one or more outputs from one stage functions as an input to another stage. The coupling works in both directions, as indicated by the arrows in the diagram below. In this activity, you will identify the compounds that couple the stages of cellular respiration.
| back 10 look at item 6a |
front 11 Under anaerobic conditions (a lack of oxygen), the conversion of pyruvate to acetyl CoA stops.
| back 11 In the absence of oxygen, electron transport stops. NADH is no longer converted to NAD+, which is needed for the first three stages of cellular respiration. |
front 12 Suppose that a cell’s demand for ATP suddenly exceeds its supply of ATP from cellular respiration.
| back 12 ATP levels would fall at first, decreasing the inhibition of PFK and increasing the rate of ATP production. |
front 13 What would happen to the cell’s rate of glucose utilization? | back 13 Glucose utilization would increase a lot. |
front 14 The electrons stripped from glucose in cellular respiration end up in which compound? | back 14 water At the end of the electron transport chain, the electrons and hydrogen atoms are added to oxygen, forming water. |
front 15 What happens at the end of the chain in the figure? | back 15 4 electrons combine with a molecule of oxygen and 4 protons. |
front 16 Match each product of pyruvate metabolism with the condition under which it is produced. | back 16 Lactate: Fermentation in human muscle
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front 17 Sort the following items according to whether they are reactants or products in the anaerobic reduction of pyruvate during lactic acid fermentation. | back 17 Reactants: NADH & Pyruvate
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front 18 In muscle cells, fermentation produces _____. | back 18 lactate and NAD+ |
front 19 In fermentation _____ is reduced and _____ is oxidized. | back 19 pyruvate ... NADH |
front 20 Which molecule is metabolized in a cell to produce energy for performing work? | back 20 Glucose |
front 21 True or false? The potential energy in an ATP molecule is derived mainly from its three phosphate groups. | back 21 True |
front 22 Which process is not part of the cellular respiration pathway that produces large amounts of ATP in a cell? | back 22 Fermentation |
front 23 Which step of the cellular respiration pathway can take place in the absence of oxygen? | back 23 Glycolysis |
front 24 Into which molecule are all the carbon atoms in glucose ultimately incorporated during cellular respiration? | back 24 Carbon dioxide |
front 25 Which of the following statements about the electron transport chain is true? | back 25 NADH and FADH2 donate their electrons to the chain. |
front 26 Which stage of glucose metabolism produces the most ATP? | back 26 Electron transport and chemiosmosis |
front 27 True or false? The reactions that generate the largest amounts of ATP during cellular respiration take place in the mitochondria. | back 27 True |
front 28 In the absence of oxygen, what is the net gain of ATP for each glucose molecule that enters glycolysis? | back 28 two ATP Four ATP are made, but two ATP are consumed to start the process of glycolysis. |
front 29 Which metabolic pathway is common to both cellular respiration and fermentation? | back 29 glycolysis |
front 30 In most cells, not all of the carbon compounds that participate in glycolysis and the citric acid cycle are converted to carbon dioxide by cellular respiration. What happens to the carbon in these compounds that does not end up as CO2? | back 30 The carbon compounds are removed from these processes to serve as building blocks for other complex molecules. |
front 31 The carbon compounds are removed from these processes to serve as building blocks for other complex molecules. | back 31 carbohydrates only. |
front 32 The immediate energy source that drives ATP synthesis by ATP synthase during oxidative phosphorylation is the | back 32 H+ concentration across the membrane holding ATP synthase. |
front 33 Which metabolic pathway is common to both fermentation and cellular respiration of a glucose molecule? | back 33 glycolysis |
front 34 In mitochondria, exergonic redox reactions | back 34 provide the energy that establishes the proton gradient. |
front 35 The final electron acceptor of the electron transport chain that functions in aerobic oxidative phosphorylation is | back 35 oxygen |
front 36 What is the oxidizing agent in the following reaction? Pyruvate + NADH + H+ → Lactate + NAD+ | back 36 pyruvate |
front 37 When electrons flow along the electron transport chains of mitochondria, which of the following changes occurs? | back 37 The pH of the matrix increases. |
front 38 Most CO2 from catabolism is released during | back 38 the citric acid cycle. |
front 39 Which of the following statements accurately describes the function of a metabolic pathway involved in cellular respiration? | back 39 The function of glycolysis is to begin catabolism by breaking glucose into two molecules of pyruvate, with a net yield of two ATP.
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front 40 In cellular respiration, a series of molecules forming an electron transport chain alternately accepts and then donates electrons. What is the advantage of such an electron transport chain? | back 40 The advantage of an electron transport chain is that a small amount of energy is released with the transfer of an electron between each pair of intermediates. |
front 41 How will a healthy individual’s ATP production change during an eight-hour fast? | back 41 The individual’s ATP production will not change significantly. |
front 42 Identify all correct statements about the basic function of fermentation.
| back 42 The basic function of fermentation is the regeneration of NAD+, which allows continued ATP production by glycolysis.
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front 43 Select the correct statement about cellular respiration. | back 43 Cellular respiration and breathing differ in that cellular respiration is at the cellular level, whereas breathing is at the organismal level. |