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ch 13

front 1 How do all viruses differ from bacteria? -Viruses are not composed of cells. -Viruses are filterable. -Viruses are obligate intracellular parasites. -Viruses do not have any nucleic acid. -Viruses do not reproduce.	back 1 -Viruses are not composed of cells.
front 2 A feature that may be found in viruses but never in bacteria is -an ability to infect more than one type of host. -they cannot reproduce themselves outside a host. -the ability to pass through 0.22 micrometer pore filters. -may contain an RNA genome. -a sensitivity to antibiotics	back 2 -may contain an RNA genome
front 3 Which of the following statements about viral spikes is FALSE? -They may cause hemagglutination. -They bind to receptors on the host cell surface. -They are found only on nonenveloped viruses. -They are used for attachment. -They are composed of carbohydrate-protein complexes	back 3 -They are found only on nonenveloped viruses.
front 4 Which of the following is NOT used as a criterion to classify viruses? -biochemical tests -size -morphology -nucleic acid -number of capsomeres	back 4 - biochemical tests

front 5 Which of the following is NOT utilized to culture viruses? -embryonated eggs -animal cell cultures -laboratory animals -culture media -bacterial cultures	back 5 -culture media
front 6 Bacteriophages and animal viruses do NOT differ significantly in which one of the following steps -release -uncoating -penetration -attachment -biosynthesis	back 6 -biosynthesis
front 7 The definition of lysogeny is -when the burst time takes an unusually long time. -attachment of a phage to a cell. -phage DNA is incorporated into host cell DNA. -lysis of the host cell due to a phage. -the period during replication when virions are not present.	back 7 -phage DNA is incorporated into host cell DNA.
front 8 A viroid is a(n) -infectious protein. -provirus. -capsid without nucleic acid. -complete, infectious virus particle. -infectious piece of RNA without a capsid.	back 8 - infectious piece of RNA without a capsid.

front 9 In Figure 13.1, which structure is a complex virus? -a -b -c -d -All of the structures are complex viruses.	back 9 - b
front 10 The morphological types of viruses illustrated in Figure 13.1 are ultimately determined by the -membrane spikes. -capsomeres. -viroids. -envelope. -nucleic acid.	back 10 - nucleic acid
front 11 A clear area against a confluent "lawn" of bacteria is called a -rash. -cell lysis. -plaque. -pock. -phage.	back 11 - plaque
front 12 Continuous cell lines differ from primary cell lines in that -continuous cell lines always have to be re-isolated from animal tissues. -viruses can be grown in continuous cell lines. -continuous cell lines can be maintained through an indefinite number of generations. -continuous cell lines are from human embryos. -continuous cell lines are derived from primary cell lines.	back 12 - continuous cell lines can be maintained through an indefinite number of generations.

front 13 Which of the following is necessary for replication of a prion? - lysozyme -DNA polymerase -DNA -PrPSc -RNA	back 13 - PrPSc
front 14 A persistent infection is one in which -host cells are transformed. -host cells are gradually lysed. -the virus remains in equilibrium with the host without causing a disease. -the disease process occurs gradually over a long period. -viral replication is unusually slow.	back 14 - the disease process occurs gradually over a long period.
front 15 An example of a persistent viral infection is -Varicellavirus infection. -Influenza. -Herpes Simplex Virus infection. -Hepatitis A infection. -Human Immunodeficiency Virus infection	back 15 - Varicellavirus infection.
front 16 Lysogeny can result in all of the following EXCEPT -immunity to reinfection by the same phage. -immunity to reinfection by any phage. -acquisition of new characteristics by the host cell. -specialized transduction. -phage conversion.	back 16 - immunity to reinfection by any phage.

front 17 Which of the following would be the first step in biosynthesis of a virus with a - (minus) strand of RNA? -synthesis of double-stranded RNA from a DNA template -transcription of mRNA from DNA -synthesis of double-stranded RNA from an RNA template -synthesis of DNA from an RNA template -synthesis of DNA from a DNA template	back 17 - synthesis of double-stranded RNA from an RNA template
front 18 An infectious protein is a -retrovirus. -viroid. -papovavirus. -prion. -bacteriophage.	back 18 - prion
front 19 An envelope is acquired during which of the following steps? -biosynthesis -release -adsorption -penetration -uncoating	back 19 - release
front 20 Which of the following statements is NOT true of lysogeny? -Lytic cycle may follow lysogeny. -Prophage is inserted into the host genome. -It causes lysis of host cells. -It can give infected pathogens the genetic information for toxin production. -It is a "silent" infection; the virus does not replicate.	back 20 - It causes lysis of host cells.

front 21 An example of a latent viral infection is -subacute sclerosing panencephalitis. -cold sores. -smallpox. -influenza. -mumps.	back 21 - cold sores
front 22 A virus's ability to infect an animal cell depends primarily upon the -host cell's ability to phagocytize viral particles. -enzymatic activity of a host cell. -type of viral nucleic acid. -presence of receptor sites on the cell membrane. -presence of pili on the host cell wall.	back 22 - presence of receptor sites on the cell membrane.
front 23 Assume you have isolated an unknown virus. This virus has a single, positive sense strand of RNA, and possesses an envelope. To which group does it most likely belong? -herpesvirus -retrovirus -togavirus -picornavirus -papovavirus	back 23 - togavirus
front 24 The mechanism whereby an enveloped virus leaves a host cell is called -abduction. - penetration. -lysogeny. -transduction. -budding.	back 24 -budding

front 25 The most conclusive evidence that viruses cause cancers was provided by -the presence of antibodies against viruses in cancer patients. -finding oncogenes in viruses. -cancer that developed in chickens following injection of cell-free filtrates. -treating cancer with antibodies. -some liver cancer patients having had hepatitis.	back 25 - cancer that developed in chickens following injection of cell-free filtrates.
front 26 Bacteriophages derive all of the following from the host cell EXCEPT -ATP. -amino acids. -nucleotides. -lysozyme. -tRNA.	back 26 - lysozyme
front 27 Bacteriophage replication differs from animal virus replication because only bacteriophage replication involves -replication of viral nucleic acid. -injection of naked nucleic acid into the host cell. -assembly of viral components. -lysis of the host cell. -adsorption to specific receptors.	back 27 - injection of naked nucleic acid into the host cell.
front 28 Generally, in an infection caused by a DNA-containing virus, the host animal cell supplies all of the following EXCEPT - tRNA. -RNA polymerase. -nucleotides. -DNA polymerase. -None of the answers are correct; all of these are supplied by the host animal cell.	back 28 - DNA polymerase.

front 29 Which of the following places these items in the correct order for DNA-virus replication? 1. Maturation 2. DNA synthesis 3. Transcription 4. Translation - 1; 2; 3; 4 - 3; 4; 1; 2 - 4; 1; 2; 3 -2; 3; 4; 1 -4; 3; 2; 1	back 29 - 2; 3; 4; 1
front 30 A viral species is a group of viruses that -has the same genetic information and ecological niche. -infects the same cells and cause the same disease. -has the same morphology and nucleic acid. -cannot be defined.	back 30 - has the same genetic information and ecological niche.
front 31 Viruses that utilize reverse transcriptase belong to the virus families -Retroviridae and Picornaviridae. -Hepadnaviridae and Retroviridae. -Rhabdoviridae and Herpesviridae. -Herpesviridae and Retroviridae. -Herpesviridae and Poxviridae.	back 31 - Hepadnaviridae and Retroviridae.
front 32 DNA made from an RNA template will be incorporated into the virus capsid of - influenzavirus. -Retroviridae. -Hepadnaviridae. -Herpesviridae. -bacteriophage families.	back 32 - Hepadnaviridae.

front 33

Which of the following statements about viruses is FALSE?
-Viruses use their own catabolic enzymes.

-Viruses use the anabolic machinery of the cell.

-Viruses contain a protein coat.

-Viruses contain DNA or RNA but never both.

-Viruses have genes.

back 33

- Viruses use their own catabolic enzymes.

front 34

A lytic virus has infected a patient. Which of the following would best describe what is happening inside the patient?
-The virus is infecting cells and then releasing only small amounts of virus.

-The virus is incorporating its nucleic acid with that of the patient's cells.

-The virus is slowly killing the patient's cells.Correct!

-The virus is causing the death of the infected cells in the patient.

-The virus is not killing any cells in the host.

back 34

- The virus is causing the death of the infected cells in the patient.

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ch 13