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Exam 3 questions

front 1

Ouabain, an inhibitor of the Sodium Potassium Pump, is a _________ that inhibits the pump by binding to the _______ part of the transporter.

back 1

cardiac glycoside, extracellular

front 2

Which of these structures correctly represents a glycerophospholipid?

back 2

Structure A

front 3

The convention for drawing the structure of disaccharides is to draw the _______ end on the left, and the ______ end on the right.

back 3

non-reducing, reducing

front 4

All of the following is (are) found as covalently attached anchors in lipid-linked proteins, EXCEPT:

A) glycosylphosphatidyl inositol

B) cholesterol and other sterols

C) isoprenes

D) All of the above are found as covalently attached anchors in lipid-linked proteins.

E) fatty acids

back 4

cholesterol and other sterols

front 5

Peptidoglycans are primarily found in

back 5

Bacterial cell walls

front 6

Which of the following is true about membrane glycoproteins?

A) They increase the hydrophobicity of the membrane.

B) They function primarily in energy storage.

C)They are located exclusively on the inner leaflet of the plasma membrane.

D)They serve as solute transporters in the membrane.

E)They play a key role in cell recognition and communication.

back 6

They play a key role in cell recognition and communication.

front 7

What describes why plant oils are generally healthier for human consumption than animal fats?

back 7

Plant oils usually contain more unsaturated fatty acids than animal fats

front 8

Lactose is made up of which of the following monosaccharides?

back 8

Glucose and Fructose

front 9

Which of the following segments of the integral membrane protein glycophorin most likely contains the transmembrane alpha helix?

A) SQTNDTHKRDTYAATPRA

B) LSTTEVAMHTTTSSSVSKSY

C) ITLIIFVMAILVIAFMILLI

D) VSEISVRTVYPPEEETGE

E) YGIRRLIKKSPSDVKPLP

back 9

C) ITLIIFVMAILVIAFMILLI

front 10

What correctly describes monosaccharide isomers?

back 10

Formation of a hemiacetal, or a hemiketal, creates a new chiral center.

front 11

Identify the compound

back 11

sphingomylelin

front 12

Which of the following are used for energy storage?

A) Fatty Acids

B) Glycerophospholipds

C) Cholesterol

D) Sphingolipids

E)Triacylglycerols

back 12

Triacylglycerols

front 13

How many reducing ends does glycogen have?

back 13

One

front 14

What can form a cyclic hemiketal?

back 14

Fructose

front 15

What does transverse asymmetry mean in the context of membrane structure?

back 15

The composition of the inner leaflet and outer leaflet of the bilayer are different

front 16

Which of the following pairs are epimers?

back 16

glucose and mannose

front 17

AcrB is a(n) ____ that transport drugs out of the cell ____ their concentration gradient using energy from protons entering the cell ____ their concentration gradient.

back 17

secondary active transporter; up; down

front 18

Which Fisher Projection represents the same monosaccharide as the Haworth Projection?

back 18

C

front 19

What is the position of the hydroxyls on the chiral carbons of D-fructose in the linear structure (Fischer projection)?

back 19

Left, right, right

front 20

Amide-linked ____ anchors are covalently attached to the ____ of ____ residues on proteins.

back 20

myristoyl; alpha amino group; glycine

front 21

The sodium potassium pump transports 3 Na+ ions ___ and 2 K+ ions ___ for every 1 molecule of ATP hydrolyzed.

back 21

out of the cell; into the cell

front 22

Which of the following is an example of a monosaccharide?Correct answer:

A)Galactose

B) Sucrose

C) Maltose

D)Amylose

E)Lactose

back 22

A)Galactose

front 23

Which of the following statement about cell membrane states is TRUE?

A) Lipid rafts phase separate in single monolayers in the liquid-ordered state.

B) The liquid-ordered state predominates below the melting temperature of a membrane.

C) The solid-ordered state predominates above the melting temperature of a membrane.

D)Thioether linked proteins are found in the liquid-ordered state.

E) The liquid-ordered state can only be made up of lipids with unsaturated fatty acid tails.

back 23

A) Lipid rafts phase separate in single monolayers in the liquid-ordered state.

front 24

____ and ____ increase melting temperatures of fatty acids and lipids that contain them

back 24

Saturation; longer acyl chains

front 25

What polysaccharide is a branched polymer?

back 25

amylopectin

front 26

Starch is a mixture of

back 26

amylose and amylopectin

front 27

The monosaccharide used to make glycogen is _____, while the monosaccharide used to make RNA is _____ and DNA is _____.

back 27

glucose; ribose; deoxyribose

front 28

Peripheral membrane proteins are

back 28

Bound to integral membrane proteins or polar head groups of lipids

front 29

O-linked oligosaccharides are important on glycoproteins in order to

back 29

lift the protein functional domains above the glycocalyx.

front 30

What type of glycosidic bond is found in maltose?

back 30

α(1→4)

front 31

In glycoproteins, O-linked oligosaccharides are commonly attached to the —OH group of _____.

back 31

threonine

front 32

Which label points to the point of attachment for a fatty acid to yield a ceramide?

back 32

A

front 33

Which of the following is an example of a heteropolysaccharide?

back 33

hyaluronic acid

front 34

The bonding of alcohols to the anomeric center of a carbohydrate results in the formation of a(n) __________ bond.

back 34

glycosidic

front 35

What is true concerning the polysaccharide shown above?

back 35

The branch point illustrated occurs more often in glycogen than it does in amylopectin.

front 36

Which type of lipid-anchor is an isoprene-based lipid and connected to side-chain Cys residues?

back 36

Thioether-linked anchors

front 37

The role of cartilage matrix proteoglycan is

back 37

to expel water upon compression and absorb water upon decompression.

front 38

Which of the following structures is formed by fatty acids and other single tailed amphiphiles?

back 38

micelles

front 39

Lipid bilayers with high concentrations of gangliosides are rare. Which of the following explanations is correct?

A)The hydrophobic tails on gangliosides form a conical shape rather than a cylindrical shape making close packing difficult.

B) Gangliosides contain trans fatty acids resulting in a bent hydrophobic tail making close packing difficult.

D) None of the above is correct.

E) Gangliosides contain large headgroups making close packing difficult.

back 39

Gangliosides contain large headgroups making close packing difficult.

front 40

Which of the following modes of transport exhibits saturation, at very high solute concentration?

back 40

-Facilitated diffusion

- Secondary active transport

-Primary active transport

-Ion channels

front 41

All of the following describe the solid ordered (So) phase of a lipid bilayer EXCEPT:

A) Tight packing

B) Maximal bilayer thickness

C) Found at temperatures below Tm

D)Lipid chains likely to be bent

back 41

D) lipid chains likely to be bent

front 42

ALL of the following are components of the cartilage matrix proteoglycan, EXCEPT:

A) O-linked oligosaccharides, Not SelectedCorrect answer:

B)Transmembrane domain

C)Chondroitin sulfate

D)N-linked oligosaccharides

E)Keratan sulfate

back 42

B)Transmembrane domain

front 43

All of the following are components of membranes EXCEPT:

A)Triacylglycerols

B) Proteins

C) Sphingolipids

D)Glycerophospholipids

E) Cholesterol

back 43

Triacylglycerols

front 44

A membrane surface protein with a keratan sulfate linkage is classified as a

back 44

Proteoglycan

front 45

Which of the following amino acid residues is thermodynamically favored at the lipid-water interface of a membrane?

back 45

Tryptophan

front 46

Proteins that bind to specific carbohydrates are called ______.

back 46

lectins

front 47

Two of the following are linear polysaccharides made up of glucose monomers:
______ is a structural polysaccharide, while _____ is for storage.

back 47

cellulose, amylose

front 48

Which carbon in D-glucose determines its D or L configuration?

back 48

C-5

front 49

Which of the following can be predicted using hydropathy plots?

back 49

Transmembrane alpha helices

front 50

Which of the these is the C-2 epimer of D-glucose?

Note that the identifying Roman Numeral is below each monosaccharide structure.

back 50

III