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EXAM 3 - Muscle Physiology

front 1

Define isometric contraction

back 1

the tension generated does not overcome the load, so there is no visible shortening of the muscle fiber (although crossbridge cycling is happening)

front 2

define isotonic contraction

back 2

the tension generated DOES overcome the load, so there is measurable shortening of the fiber.

front 3

What is another word for "thick filaments"

back 3

Myosin

front 4

What is another word for "thin filaments"

back 4

Actin

front 5

During sarcomere contraction, which of the following does NOT change length?

a) the distance between the Z-lines

b) the length of the I bands

c) the length of the A-bands

d) none of the above change length

back 5

c) the length of the A-bands

front 6

During sarcomere contraction, Ca binds to ______________ , which allows ______________to move and reveal the ______________ active sites for crossbridge formation.

back 6

troponin; tropomysin; actin

front 7

Order of Crossbridge Formation:

back 7

1. AP reaches T-tubules

2. Ca is released from the SR

3. Ca binds to troponin

4. Tropomyosin moves to reveal active sites

5. Crossbridge Forms

front 8

Which one of the following components stimulates contraction of a skeletal muscle?

a) muscle fiber

b) motor neuron

c) acetylcholinesterase

d) synaptic cleft

back 8

b) motor neuron

front 9

Which structure of the neuromuscular junction is a chemically-gated ion channel that the neurotransmitter binds to?

a) voltage-gated sodium channel

b) voltage-gated calcium channel

c) acetylcholine receptor

d) synaptic vesicle

back 9

c) acetylcholine receptor