front 1 Which test confirms the integrity of a filter that will be used for terminal sterilization? | back 1 Bubble-point test |
front 2 The Continental (dry gum) and the English (wet gum) are methods of preparing which type of dosage form? | back 2 Emulsions |
front 3 The multi-dose vial of Herceptin will be used to prepare doses for multiple patients. What is the risk level of the Herceptin admixtures? | back 3 Medium-risk Using a multi-dose vial to prepare multiple doses is considered medium-risk. To prepare multiple doses, the compounder will need to enter the same vial multiple times, increasing the risk of contamination. |
front 4 Which of the following is a correct statement about withdrawing Herceptin from a vial when a closed-system transfer device (CSTD) is not available? | back 4 Air should not be injected into the Herceptin vial before drug removal |
front 5 Compounding Method
What technique should be used in step 3 of the instructions? | back 5 Geometric dilution |
front 6 Which of the following drugs do NOT have a CSP risk level assigned by USP? (Select ALL that apply.) | back 6 Fluconazole in dextrose 400 mg/200 mL premixed bag Meropenem in NS 500 mg/50 mL ready-to-use drug delivery system |
front 7 Rank the following steps used to compound molded tablets in the correct order. (Left-click to drag and order the answer options; the first step must be placed in the top box. ALL options must be used.) | back 7
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front 8 Place the following steps for making an ointment in the correct order. (Left-click to drag and order the answer options; the first step must be placed in the top box. ALL options must be used.) | back 8
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front 9 The pharmacy receives a prescription for 100 grams of 5% hydrocortisone ointment. The pharmacy has a 10% hydrocortisone ointment and a 2.5% hydrocortisone ointment available. Using only these products, how many grams of the 10% ointment should be used to compound this prescription? (Answer must be numeric; no units or commas; round the final answer to the nearest ONE DECIMAL PLACE.) | back 9 33.3 |
front 10 A technician is preparing the label for a calamine-zinc oxide
ointment he has prepared. If today's date is January 31, 2022, what is an appropriate BUD for this compounded product? | back 10 April 30, 2022 The BUD for non-sterile, non-aqueous formulations is up to 6 months from the date of preparation. Calamine expires 4/2022, which is sooner than 6 months; therefore, the BUD is April 30, 2022. |
front 11 Which statement is correct regarding the use of intravenous (IV) medications in the hospital setting? | back 11 The pH of IV solutions should be close to neutral (pH of 7) |
front 12 The pharmacy technician would like to prepare an emulsion using the Continental gum method (also known as the dry gum method). Place the steps that the technician will need to take in the correct order. (Left-click to drag and order the answer options; the first step must be placed in the top box. ALL options must be used.) | back 12 1. Levigate the gum with oil |
front 13 Due to a nationwide shortage of sodium bicarbonate injection, a pharmacist is looking at the possibility of using non-sterile sodium bicarbonate powder to compound sterile intravenous sodium bicarbonate. What beyond-use date should be on the label if the final preparation will be stored at room temperature? | back 13 24 hours High-risk sterile compounding uses non-sterile ingredients or equipment. The beyond-use date for a high-risk CSP stored at room temperature is 24 hours. |
front 14 Which of the following can be used for sterility testing of high-risk compounded sterile products (CSPs)? (Select ALL that apply.) | back 14 Tryptic soy broth Fluid thioglycollate medium Bacterial endotoxin test |
front 15 The technician has finished compounding a doxycycline IV admixture. Which of the following must be included on the label? (Select ALL that apply.) | back 15 Name and concentration of ingredients Route of administration Storage information Appropriate auxiliary labels |
front 16 The pharmacist is preparing intravenous conventional amphotericin B for a patient with AIDS with invasive aspergillosis. What diluent should be used to reconstitute the drug? | back 16 Sterile water for injection |
front 17 All of the following must be documented in the compounding record EXCEPT: | back 17 When the compounding area was last cleaned |
front 18 A pharmacy technician is compounding cefazolin 2 g in 50 mL of D5W for intravenous infusion. How should the pharmacist verify that the correct volume of ingredients was used in the preparation? | back 18 Direct visualization of the syringe before compounding |
front 19 The density factor is needed to prepare which formulation type? | back 19 Suppository |
front 20 A compounding pharmacist receives a prescription for thirty 60 mcg levothyroxine (T4) capsules. How many 150 mcg tablets will he need to compound this prescription? (Answer must be numeric; no units or commas; round the final answer to the nearest WHOLE number.) | back 20 12 30 x 60 mcg caps = 1800 mcg needed 1800 mcg / 150 mcg per cap = 12 capsules needed |
front 21 The pharmacy receives a prescription for 50 grams of 5% salicylic acid ointment. The pharmacy has a 30% salicylic acid ointment and petrolatum available. Using only these products, how many grams of petrolatum should be used to compound the prescription? (Answer must be numeric; no units or commas; round the final answer to the nearest ONE DECIMAL PLACE.) | back 21 41.7 (50 g)(5%) = (x)(30%)x = 8.3 g |
front 22 Which document provides directions on how to make a calamine-zinc oxide ointment? | back 22 Master formula |
front 23 Stability: A beyond-use date of 56 days can be used for this preparation only when it is stored in a refrigerator. The reported stability study used the injection as the source of the drug Today's date is January 31st. What is an appropriate BUD for this compounded preparation if it is stored in the refrigerator? | back 23 March 28th |
front 24 Put the required steps to complete preparation item #2 and #3 in the correct order? (Left-click to drag and order the answer options; the first step must be placed in the top box. ALL options must be used.) | back 24 1. Inject 50 ml of air into the vial of 0.9% sodium chloride |
front 25 A pharmacist has received an order to compound 200 mg progesterone suppositories. She will use a white, amorphous low density progesterone powder that aerosolizes easily. The master formulation record includes the following
ingredients: In the formula above, what is the purpose of the sodium lauryl sulfate? | back 25 Surfactant, charge neutralizer |
front 26 What is the most commonly used dosage form for manufactured oral medications? | back 26 Compressed tablets |
front 27 A pharmacy technician reconstitutes a single-dose vial of cefazolin and transfers it to a 50 mL bag of D5W. The dose is prepared in an ISO 5 horizontal airflow workbench, which is located in an ISO 7 cleanroom with an ISO 8 anteroom. What beyond-use date should be on the label if the cefazolin will be stored in the refrigerator? | back 27 14 days The BUD date for a low-risk CSP stored in the refrigerator is 14 days. |
front 28 A multi-dose vial of ondansetron is being used to prepare doses for multiple patients at the same time. The doses are prepared in an ISO 5 laminar airflow workbench, which is located in an ISO 7 cleanroom with an ISO 8 anteroom. According to USP 797, what BUD should be assigned to these IV admixtures if stored at room temperature? | back 28 30 hours Batch preparation requires multiple entries into the same vial, which increases the risk of contamination. Batching is considered medium-risk compounding, and the BUD for medium-risk CSPs stored at room temperature is 30 hours. |
front 29 A pharmacist needs to prepare a 4% hydrocortisone ointment to treat a
rash on a patient’s forearms and to protect the skin from drying. The compound is being prepared on January 1st. The earliest expiration date of any ingredients is December 30th of that same year. What is the beyond-use date (BUD) of the hydrocortisone ointment (assuming all are within the same year)? | back 29 July 1st The BUD of non-sterile, nonaqueous formulations is up to 6 months from the preparation date. If any of the ingredients expire before 6 months, the earlier expiration date should be used. |
front 30 Place the following steps for making the hydrocortisone ointment in the correct order. (Left-click to drag and order the answer options; the first step must be placed in the top box. ALL options must be used.) | back 30 1. Weigh the hydrocortisone powder 2. Plave the powder on an ointment slab. 3. Add a small amount of mineral oil to the powder 4. Levigate the powder using an ointment slab and spatula 5. Add petrolatum using geometric dilution |
front 31 The pharmacist has prepared 60 g of the 4% hydrocortisone ointment and is concerned that the strength is too strong for the patient’s thin, cracked skin. How much petrolatum should be added to reduce the strength to 2.4%? | back 31 40 g (60 g)(4%) = (x)(2.4%)x = 100 g 100 g - 60 g = 40 g |
front 32 The pharmacist does not have enough petrolatum to use for the above preparation. The pharmacist will prepare 60 grams of the 2.4% by combining the 4% hydrocortisone ointment with a 1.5% hydrocortisone ointment the pharmacy has in stock. How many grams of each ointment will be required? | back 32 21.6 g 4%, 38.4 g 1.5% |
front 33 The pharmacist receives the following compound prescription on March 5th. The pharmacist notes that the Ora-Plus expires on 4/30 of this year and the spironolactone/hydrochlorothiazide tablets expire on 6/30 of this year. Assuming the product is packaged and stored correctly, which beyond use date is correct for this product? | back 33 March 19th |
front 34 **case above** Which auxiliary label must be placed on the final product? | back 34 shake well before using |
front 35 Which of the following compounded preparations would have the shortest beyond use date? | back 35 A water-containing oral solution that is stored in the refrigerator |
front 36 A pharmacist is compounding an emulsion by first combining acacia (gum) with water to form a mucilage and then slowly adding the oil to form the emulsion. What is this process called? | back 36 English method |
front 37 A technician is compounding a minoxidil 5% and finasteride 0.1%
topical liquid with the following
ingredients: | back 37 Geometric dilution |
front 38 A pharmacy technician is preparing amiodarone 150 mg in 100 mL D5W for intravenous infusion. After swabbing the rubber stopper of the amiodarone vial with alcohol, what is the correct order of the steps he should take to correctly remove the drug from the vial? (Left-click to drag and order the answer options; the first step must be placed in the top box. ALL options must be used.) | back 38 1. Pull back the syringe plunger to draw up the volume of air that is
equal to the desired volume of amiodarone |
front 39 According to USP 797, what beyond-use date should be placed on the vancomycin if it is stored at room temperature? | back 39 48 hrs The vancomycin preparation is considered low-risk. The BUD for low-risk CSPs stored at room temperature is 48 hours. |
front 40 A pharmacist is compounding a hard lozenge for sore throat relief. Which of the following would be an appropriate base for the lozenge? | back 40 Sucrose |
front 41 A pharmacist is preparing a topical compound containing glycolic acid 5%, hydroquinone 1% and tretinoin 0.025% in a cream base. What is the maximum beyond-use date that can be applied to the label? | back 41 30 days The cream base indicates that it is an aqueous formulation. The beyond-use date for water-containing topical formulations is 30 days. |
front 42 JG is complaining of worsening nausea since the Exelon patch strength was increased last month. The medical director has ordered lansoprazole suspension 15 mg once daily, which the pharmacist will prepare using a compounding kit: 300 mL lansoprazole 3 mg/mL suspension Ingredients: lansoprazole 0.9 g, artificial strawberry flavor, FD&C Red #40, Magnasweet 100 (ammonium glycyrrhizate), poloxamer 188, propylene glycol, purified water, simethicone emulsion, sodium bicarbonate, sodium citrate, sucralose, benzoic acid and xanthan gum. What is the percentage strength (%w/v) of the prepared lansoprazole suspension? | back 42 0.3% 3 mg/mL = x/100 mL300 mg = 0.3 g = 0.3% |
front 43 **case above** The pharmacist will label the suspension using ratio strength. Which of the following provides the correct approximate ratio strength for the label? | back 43 1:333 lansoprazole solution 0.3 g/100 mL = 1/xx = 333 |
front 44 Which CSP risk level does NOT match the correlating non-hazardous area requirements? | back 44 low-risk; ISO 5 PEC, an ISO 8 buffer room and an ISO 8 ante area. |
front 45 Rank the following steps for preparing capsules using the punch method in the correct order. (Left-click to drag and order the answer options; the first step must be placed in the top box. ALL options must be used.) | back 45 1. Triturate the dry ingredients |