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Pharmacology Tetracyclines, Sulfonamides, and Urinary Antiseptics

front 1

What is the prototype drug for tetracyclines?

back 1

tetracycline HCL

front 2

What do all tetracyclines end in?

back 2

"-cycline"

front 3

How do tetracyclines work?

back 3

they interfere with microbial protein synthesis

front 4

What would we use tetracycline for?

back 4

it is a first line treatment for mycoplasma, chlamydia, rickettsia, and Lyme disease.

front 5

What is tetracyclines spectrum of activity?

back 5

it is broad spectrum but mainly used for some odd gram negatives

front 6

What are some nursing implications for tetracyclines?

back 6

it can cause renal failure, diminished contraceptive effects, and teeth discoloration?

front 7

Why would we not give tetracyclines for patients under 8 years old?

back 7

it interferes with bone and teeth growth

front 8

Doxycycline is a type of tetracycline. What would we use it for?

back 8

to treat anthrax

front 9

What is a prototype for Sulfanamides?

back 9

trimethoprim-sulfamethoxazole

front 10

How would you recognize a sulfonamide drug?

back 10

"sulfa"

front 11

How do sulfonamides work?

back 11

they inhibit the multiplication of bacteria

front 12

What do we use trimethoprim-sulfamethoxazole (Bactrim specifically) for?

back 12

for pneumocystis jiroveci (pneumonia in pts who are immunocompromised due to chemotherapy or late stage HIV)

front 13

What is sulfonamides spectrum of activity?

back 13

broad spectrum (S)

front 14

What are some nursing implications for sulfonamide?

back 14

DO NOT take if breastfeeding, it diminishes effects of contraception, can cause renal failure, and a sulfa allergy is common.

front 15

What is a prototype drug for urinary antiseptics?

back 15

nitrofurantoin

front 16

What do we use nitrofurantoin for?

back 16

treatment of UTIs

front 17

What is contraindicated for nitrofurantoin?

back 17

if pregnant or has poor renal function

front 18

What would you teach the patient prior to giving nitrofurantoin?

back 18

their urine may turn brown, and that it'll go back to normal after they finish taking it.