front 1 Why did the researchers perform immediate duplicate sequences on some patients? | back 1 Immediate duplicate sequences were experimental controls (technical replicates) designed to verify the accuracy of the sequ |
front 2 Why did the researchers perform sequencing at multiple time points on some patients? | back 2 Sequences taken at multiple time points enabled scientists to assess how the virus was evolving within a patient over time. |
front 3 Identify the positions of the shared mutations that enabled scientists to organize the sequences into three groups. | back 3 Positions 1, 7, 12, 13, and 14 |
front 4 Using the sequence similarities and differences among the 4 groups, can you identify the tree that accurately represents the ancestor-descendant relationships among the four groups? | back 4 - second tree option |
front 5 What did researchers conclude about the mode of transmission? | back 5 An outbreak started in Guinea, then spread to Sierra Leone through human-to-human transmission. |
front 6 viruses only | back 6 |
front 7 host cell only | back 7 |
front 8 both | back 8 |
front 9 lytic cycle | back 9 |
front 10 lysogenic cycle | back 10 |
front 11 both cycles | back 11 |
front 12 Which statements about viruses are true? | back 12
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front 13 Which of the three types of viruses shown in the figure would you expect to include a capsid(s)? | back 13 |
front 14 Emerging viruses arise by | back 14
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front 15 Which of the following descriptions correctly identifies a main structural difference between viruses with envelopes and viruses without envelopes? | back 15 Only viruses with envelopes have their contents enclosed by a layer containing lipids |
front 16 How does a virus differ from a bacterium? | back 16 Viruses, unlike bacteria, lack metabolic enzymes |
front 17 All of the statements below are true. Select the statement that best supports the view of most biologists that viruses are nonliving. | back 17 An isolated virus is unable to replicate its genes or regenerate ATP. |
front 18 In the lysogenic cycle _____. | back 18 viral DNA is replicated along with host DNA |
front 19 Cycle A is the _____ cycle and cycle B is the _____ cycle. | back 19 lytic ... lysogenic |
front 20 The lytic cycle of bacteriophage infection ends with the _____. | back 20 rupture of the bacterium |
front 21 The pointer is indicating the _____. | back 21 viral protein coat |
front 22 As a result of the lytic cycle, _____. | back 22 the host cell's DNA is destroyed |
front 23 The genetic material of HIV consists of _____. | back 23 single-stranded RNA |
front 24 Which of these binds to receptor molecules on the host cell membrane? | back 24 A |
front 25 What is the function of reverse transcriptase? | back 25 It catalyzes the formation of DNA from an RNA template. |
front 26 What is the source of a viral envelope? | back 26 host cell membrane |
front 27 Which of these is reverse transcriptase? | back 27 C |
front 28 Which of these is the viral genome? | back 28 E |
front 29 What enzyme allows a retrovirus to make DNA from an RNA template? | back 29 reverse transcriptase |
front 30 Double-stranded viral DNA is incorporated into a host cell as a _____. | back 30 provirus |
front 31 The pointer is indicating the virus's _____. | back 31 genome |
front 32 Viral DNA makes mRNA by the process of _____ | back 32 transcription |
front 33 How does HIV cause disease? | back 33 HIV kills cells that defend the body against disease. |
front 34 How do enveloped viruses differ from nonenveloped viruses? | back 34 They have a membrane-like outer covering. |
front 35 Which replicative cycle describes a virus that can integrate its genome into the host cell's genome? | back 35 Lysogenic |
front 36 Which enzyme inserts viral DNA into the host's chromosomal DNA? | back 36 Integrase |
front 37 How does HIV bind to a host cell? | back 37 The viral envelope proteins interact with CD4 and a co-receptor on the cell membrane. |
front 38 Which of the following events stimulates the production of viral particles in a host cell? | back 38 Activation of the host cell by cytokines, growth factors, or antigens. |
front 39 True or false? The human immunodeficiency virus (HIV) uses reverse transcriptase to make double-stranded RNA copies of its DNA genome. | back 39 False |
front 40 Which of the following events or characteristics is the most likely explanation for why an individual experiences regular herpesvirus-mediated cold sore or genital sore flare-ups? | back 40 Copies of the herpesvirus genome permanently maintained in host nuclei are periodically "activated." |
front 41 The host range of a virus is determined by whether ________. | back 41 the proteins on virus surface can bind with proteins on the host surface |
front 42 Which of the following characteristics is typical of the lytic cycle of a bacteriophage? | back 42 The host membrane ruptures, releasing many phages. |
front 43 Which of the following correctly describes the viral assembly process? | back 43 New viral components self-assemble without help from cellular components. |
front 44 A newly identified virus has a single-stranded RNA genome that is used as mRNA after infection. Its capsid is 25-30 nm in diameter and contains 180 identical capsomeres. Which of the following processes would be the best to follow to analyze the reproduction of this virus in a host cell? | back 44 translation rate |
front 45 Cells were infected with approximately 1,000 copies of either virus A
or virus B at the 0 time point. At five-minute intervals, a sample of
the virus and cell mixture was removed. All intact cells were removed
from the sample, and the number of viruses per milliliter of culture
was determined. | back 45 60 minutes |
front 46 Which of the following best explains the results? | back 46 Virus P is capable of both lysogenic and lytic cycles. |
front 47 Viruses require host cell's machinery to make copies of themselves. However, some viruses that infect humans require mechanisms that do not normally occur in human cells. Which of the following describes how the viruses can replicate in human cells? | back 47 The viral genome codes for specialized enzymes not found in the host cells. |
front 48 Oseltamivir (Tamiflu), an antiviral drug prescribed for the flu, inhibits the enzyme neuraminidase. How could this drug prevent infection in someone exposed to the flu or shorten the course of flu in an infected patient (the reasons for which it is prescribed)? | back 48 Inhibiting neuraminidase blocks the release of new viruses from infected cells. |
front 49 Which of the following statements correctly describes vaccines and how they help prevent viral infection? | back 49 Vaccines are inactive versions of a virus that stimulate an immune reaction in a person. |
front 50 A researcher is studying a single plant infected with tobacco mosaic virus (TMV). She crushes three of the plant's leaves in a small amount of water and stores the sample in the refrigerator overnight. The next day she sprays the mixture onto a new set of tobacco plants she had recently trimmed and repotted. Which of the following results will most likely occur? | back 50 The plants would develop the typical symptoms of TMV infection and would be able to transmit the disease. |
front 51 A person is most likely to recover from a cold due to viral infection if the infected cells are able to perform which of the following processes? | back 51 normal cell division |
front 52 Which of the following statements best reflects what we know about how influenza virus moves between species? | back 52 An animal, such as a pig, is infected with more than one strain of the influenza virus and the genomes reassort into new combinations that can facilitate spread to other species. |
front 53 An infectious substance capable of causing disease in plants is isolated and researchers want to determine whether the substance is a bacterium or a virus. Which of the following methods will best allow them to determine the type of infectious agent they have isolated? | back 53 Culture the substance on nutritive medium, away from any plant cells. |