front 1 1) In eukaryotic cells, chromosomes are composed of _____. A) DNA and RNA D) DNA and phospholipids | back 1 C |
front 2 2) What is the final result of mitosis in a human? A) genetically identical 2n somatic cells D) genetically identical 2n gamete cells | back 2 A |
front 3 3) Starting with a fertilized egg (zygote), a series of five cell
divisions would produce an early embryo with how many cells? C) 32 | back 3 C |
front 4 5) Scientists isolate cells in various phases of the cell cycle. They find a group of cells that have 1.5 times more DNA than G1 phase cells. The cells of this group are _____. A) between the G1 and S phases in the cell cycle B) in the G2 phase of the cell cycle | back 4 D |
front 5 6) The first gap in the cell cycle (G1) corresponds to _____. A) normal growth and cell function | back 5 A |
front 6 8) In human and many other eukaryotic species' cells, the nuclear
membrane has to disappear to permit _____. C) the splitting of the centrosomes | back 6 B |
front 7 11) Kinetochore microtubules assist in the process of splitting centromeres by _____. A) using motor proteins to split the centromere at specific
arginine residues D) phosphorylating the centromere, thereby changing its conformation | back 7 B |
front 8 13) How is plant cell cytokinesis different from animal cell
cytokinesis? | back 8 B |
front 9 14) FtsZ is a bacterial cytoskeletal protein that forms a contractile
ring involved in bacterial cytokinesis. Its function is analogous to
_____. C) the mitotic spindle of eukaryotic cells | back 9 A |
front 10 15) At which phase are centrioles beginning to move apart in animal cells? A) anaphase D) prophase | back 10 D |
front 11 16) If there are 20 centromeres in a cell at anaphase, how many
chromosomes are there in each daughter cell following
cytokinesis? C) 40 | back 11 A |
front 12 17) Taxol is an anticancer drug extracted from the Pacific yew tree.
In animal cells, Taxol disrupts microtubule formation. Surprisingly,
this stops mitosis. Specifically, Taxol must affect _____. | back 12 A |
front 13 18) Which of the following are primarily responsible for cytokinesis
in plant cells but not in animal cells? C) actin and myosin | back 13 B |
front 14 19) Movement of the chromosomes during anaphase would be most
affected by a drug that prevents _____. C) shortening of microtubules | back 14 C |
front 15 22) The beginning of anaphase is indicated by which of the following? A) Chromatids lose their kinetochores. D) Spindle microtubules begin to polymerize. | back 15 C |
front 16 23) During which phase of mitosis do the chromatids become chromosomes? A) telophase D) metaphase | back 16 B |
front 17 24) A cleavage furrow is _____. | back 17 C |
front 18 27) If the cell whose nuclear material is shown in the accompanying
figure continues toward completion of mitosis, which of the following
events would occur next? C) formation of telophase nuclei | back 18 C |
front 19 Several organisms, primarily protists, have what are called intermediate mitotic organization. 32) These protists are intermediate in what sense? | back 19 C |
front 20 Several organisms, primarily protists, have what are called intermediate mitotic organization. 33) What is the most probable hypothesis about these
intermediate forms of cell division? | back 20 D |
front 21 Nucleotides can be radiolabeled before they are incorporated into newly forming DNA and, therefore, can be assayed to track their incorporation. In a set of experiments, a student—faculty research team used labeled T nucleotides and introduced these into the culture of dividing human cells at specific times. 34) Which of the following questions might be answered by using
the method described? A) How many cells are produced by the culture
per hour? D) When do spindle fibers attach to chromosomes? | back 21 B |
front 22 Nucleotides can be radiolabeled before they are incorporated into newly forming DNA and, therefore, can be assayed to track their incorporation. In a set of experiments, a student—faculty research team used labeled T nucleotides and introduced these into the culture of dividing human cells at specific times. 35) The research team used their experiments to study the
incorporation of labeled nucleotides into a culture of lymphocytes and
found that the lymphocytes incorporated the labeled nucleotide at a
significantly higher level after a pathogen was introduced into the
culture. They concluded that _____. | back 22 B |
front 23 36) Through a microscope, you can see a cell plate beginning to
develop across the middle of a cell and nuclei forming on either side
of the cell plate. This cell is most likely _____. C) an animal cell in the S phase of the cell cycle D) a plant cell in metaphase | back 23 B |
front 24 38) The drug cytochalasin B blocks the function of actin. Which of
the following aspects of the cell cycle would be most disrupted by
cytochalasin B? C) cell elongation during anaphase | back 24 D |
front 25 39) Motor proteins require which of the following to function in the
movement of chromosomes toward the poles of the mitotic
spindle? C) ATP as an energy source | back 25 C |
front 26 42) MPF is a dimer consisting of _____. A) a growth factor and mitotic factor D) cyclin and a cyclin-dependent kinase | back 26 D |
front 27 43) Cyclin-dependent kinase (Cdk) is _____. D) an enzyme that attaches phosphate groups to other proteins | back 27 D |
front 28 44) What happens if MPF (mitosis-promoting factor) is introduced into immature frog oocytes that are arrested in G2? A) Nothing happens. | back 28 C |
front 29 45) Once a cell completes mitosis, molecular division triggers must
be turned off. What happens to MPF during mitosis? C) The cyclin component of MPF is degraded. | back 29 C |
front 30 46) The M-phase checkpoint ensures that all chromosomes are attached
to the mitotic spindle. If this does not happen, cells would most
likely be arrested in _____. C) prometaphase | back 30 D |
front 31 47) Which of the following is released by platelets in the vicinity of an injury? A) PDGF D) Cdk | back 31 A |
front 32 48) Which of the following is a protein synthesized at specific times
during the cell cycle that associates with a kinase to form a
catalytically active complex? C) cyclin | back 32 C |
front 33 49) Which of the following is a protein maintained at steady levels
throughout the cell cycle that requires cyclin to become catalytically
active? C) cyclin | back 33 D |
front 34 50) Which of the following triggers the cell's passage past the G2 checkpoint into mitosis? A) PDGF B) MPF | back 34 B |
front 35 51) The cyclin component of MPF is destroyed toward the end of which phase? A) G1 B) S C) G2 D) M | back 35 D |
front 36 53) Density-dependent inhibition is explained by which of the
following? | back 36 B |
front 37 55) Anchorage dependence of animal cells in vitro or in vivo depends on which of the following? A) attachment of spindle fibers to centrioles D) response of the cell cycle controls to the binding of cell-surface phospholipids | back 37 B |
front 38 58) Cells from advanced malignant tumors often have very abnormal
chromosomes and an abnormal number of chromosomes. What might explain
the association between malignant tumors and chromosomal
abnormalities? B) Cancer cells are no longer anchorage-dependent. D) Transformation introduces new chromosomes into cells. | back 38 C |
front 39 59) Exposure of zebrafish nuclei to meiotic cytosol resulted in phosphorylation of NEP55 and L68 proteins by cyclin-dependent kinase 2. NEP55 is a protein of the inner nuclear membrane, and L68 is a protein of the nuclear lamina. What is the most likely role of phosphorylation of these proteins in the process of mitosis? A) They enable the attachment of the spindle microtubules to
kinetochore regions of the centromere. D) They assist in the movement of the centrosomes to opposite sides of the nucleus | back 39 C |
front 40 60) Density-dependent inhibition is a phenomenon in which crowded cells stop dividing at some optimal density and location. This phenomenon involves binding of a cell-surface protein to its counterpart on an adjoining cell's surface. A growth inhibiting signal is sent to both cells, preventing them from dividing. Certain external physical factors can affect this inhibition mechanism. Select the statement that makes a correct prediction about
natural phenomena that could occur during the cell cycle to prevent
cell growth. B) As cells become more numerous, the protein kinases they
produce begin to compete with each other until only one cell has the
proteins necessary for growth. D) As cells become more numerous, more and more of them enter the synthesis part of the cell cycle and duplicate DNA to inhibit cell growth. | back 40 C |
front 41 1) If a horticulturist breeding gardenias succeeds in having a single
plant with a particularly desirable set of traits, which of the
following would be her most probable and efficient route to
establishing a line of such plants? B) Breed this plant with another plant with much weaker traits C) Clone the plant. | back 41 C |
front 42 2) Which of the following defines a genome? | back 42 D |
front 43 4) Quaking aspen can send out underground stems for asexual
reproduction. Sexual reproduction is not as common, but when it does
happen, the haploid gametes have 19 chromosomes. How many chromosomes
are in the cells of the underground stems? B) 10 | back 43 D |
front 44 5) Which of the following is a true statement about sexual vs.
asexual reproduction? B) In sexual reproduction, individuals transmit half of their
nuclear genes to each of their offspring. | back 44 B |
front 45 7) Which of the following is true of a species that has a chromosome number of 2n = 16? A) The species is diploid with 32 chromosomes per cell. D) A gamete from this species has four chromosomes. | back 45 C |
front 46 8) Eukaryotic sexual life cycles show tremendous variation. Of the
following elements, which do all sexual life cycles have in
common? III. Fertilization | back 46 B |
front 47 9) In a plant's sexual life cycle _____. | back 47 B |
front 48 13) Which of the following might result in a human zygote with 45
chromosomes? A) an error in either egg or sperm meiotic
anaphase D) incomplete cytokinesis during spermatogenesis after meiosis I | back 48 A |
front 49 14) In a human karyotype, chromosomes are arranged in 23 pairs. If we
choose one of these pairs, such as pair 14, which of the following do
the two chromosomes of the pair have in common? B) length, centromere position, and staining pattern only | back 49 C |
front 50 19) Homologous chromosomes _____. A) are identical B) carry information for the same traits C) carry the same alleles D) align on the metaphase plate in meiosis II | back 50 B |
front 51 23) If a cell has completed meiosis I and is just beginning meiosis
II, which of the following is an appropriate description of its
contents? C) It has one-fourth the DNA and one-half the chromosomes as the originating cell. D) It is identical in content to another cell formed from the same meiosis I event. | back 51 A |
front 52 25) After telophase I of meiosis, the chromosomal makeup of each daughter cell is _____. A) diploid, and the chromosomes are each composed of a single
chromatid D) haploid, and the chromosomes are each composed of two chromatids | back 52 D |
front 53 26) How do cells at the completion of meiosis compare with cells that
are in prophase of meiosis I? They have _____. C) half the number of chromosomes and one-fourth the amount of DNA. D) half the amount of cytoplasm and twice the amount of DNA. | back 53 C |
front 54 27) Which of the following happens at the conclusion of meiosis I? A) Homologous chromosomes of a pair are separated from each other. B) The chromosome number per cell remains the same. | back 54 A |
front 55 28) Sister chromatids separate from each other during _____. A) meiosis I only D) mitosis and meiosis II | back 55 D |
front 56 29) Which of the following occurs in meiosis but not in mitosis? A) chromosome replication D) condensation of chromosomes | back 56 B |
front 57 30) When we first see chiasmata under a microscope, we know that _____. A) meiosis II has occurred D) separation of homologs has occurred | back 57 C |
front 58 41) Somatic cells of roundworms have four individual chromosomes per
cell. How many chromosomes would you expect to find in an ovum from a
roundworm? C) eight | back 58 B |
front 59 42) Which of the following can occur by the process of meiosis but not mitosis? A) Haploid cells fuse to form diploid cells. D) A diploid cell combines with a haploid cell. | back 59 C |
front 60 44) What is a major difference between meiosis II and mitosis in a diploid animal? A) Homologues align on the metaphase plate in meiosis
II. C) Meiosis II occurs in a haploid cell, while mitosis occurs in diploid cells. D) Crossover takes place in meiosis II | back 60 C |
front 61 45) What is a major difference between mitosis and meiosis I in a
diploid organism? | back 61 A |
front 62 47) For the duration of meiosis I, each chromosome _____. A) is paired with a homologous chromosome C) consists of a single strand of DNA D) is joined with its homologous pair to form a synaptonemal complex | back 62 B |
front 63 51) Independent assortment of chromosomes occurs during _____ A) meiosis I only D) mitosis and meiosis II | back 63 A |
front 64 53) Independent assortment of chromosomes is a result of
_____. D) the diverse combination of alleles that may be found within any given chromosome | back 64 A |
front 65 54) When homologous chromosomes cross over, what occurs? | back 65 C |
front 66 55) How is natural selection related to sexual reproduction as opposed to asexual reproduction? A) Sexual reproduction results in many new gene combinations,
some of which will lead to differential reproduction. C) Sexual reproduction allows the greatest number of offspring to be produced. D) Sexual reproduction utilizes far less energy than asexual reproduction. | back 66 A |
front 67 56) The diploid number of a roundworm species is 4. Assuming there is no crossover, and random segregation of homologues during meiosis, how many different possible combinations of chromosomes might there be in the offspring (not including variety generated by crossing over)? A) 4 | back 67 C |
front 68 57) The bulldog ant has a diploid number of two chromosomes.
Therefore, following meiosis, each daughter cell will have a single
chromosome. Diversity in this species may be generated by mutations
and _____. B) independent assortment | back 68 C |
front 69 58) The fastest way for organisms to adapt to a changing environment involves _____. A) mutation | back 69 C |
front 70 59) Imagine that there are twenty-five different species of protists living in a tide pool. Some of these species reproduce both sexually and asexually, and some of them can reproduce only asexually. The pool gradually becomes infested with disease-causing viruses and bacteria. Which species are more likely to thrive in the changing environment? A) the sexually reproducing species | back 70 A |
front 71 60) In eukaryotes, genetic information is passed to the next
generation by processes that include mitosis or meiosis. Which of the
explanations identifies the correct process and supports the claim
that heritable information is passed from one generation to
another? B) Mitosis, followed by cytokinesis, produces daughter cells that
are genetically different from the parent cell, thus insuring
variation within the population. D) Single-celled organisms can fuse their cells, reproducing asexually through mitosis to form new cells that are not identical to the parent cell. | back 71 C |
front 72 61) Genetic variation leads to genetic diversity in populations and is the raw material for evolution. Biological systems have multiple processes, such as reproduction, that affect genetic variation. They are evolutionarily conserved and shared by various organisms. Which statement best represents the connection between
reproduction and evolution? | back 72 D |
front 73 1) What do we mean when we use the terms monohybrid cross and
dihybrid cross? | back 73 B |
front 74 2) What was the most significant conclusion that Gregor Mendel drew
from his experiments with pea plants? C) Recessive genes occur more frequently in the F1 generation than do dominant ones. D) Genes are composed of DNA. | back 74 B |
front 75 3) How many unique gametes could be produced through independent
assortment by an individual with the genotype AaBbCCDdEE? C) 16 | back 75 B |
front 76 6) Which of the following statements about independent assortment and segregation is correct? A) The law of independent assortment requires describing two or
more genes relative to one another. C) The law of independent assortment is accounted for by observations of prophase I. D) The law of segregation is accounted for by anaphase of mitosis. | back 76 A |
front 77 9) The fact that all seven of the pea plant traits studied by Mendel
obeyed the principle of independent assortment most probably indicates
which of the following? C) All of the genes controlling the traits were located on the
same chromosome. | back 77 D |
front 78 10) Mendel's observation of the segregation of alleles in gamete
formation has its basis in which of the following phases of cell
division? C) metaphase II of meiosis | back 78 D |
front 79 11) Mendel's second law of independent assortment has its basis in
which of the following events of meiosis I? C) alignment of tetrads at the equator | back 79 C |
front 80 15) Skin color in a certain species of fish is inherited via a single
gene with four different alleles. How many different types of gametes
would be possible in this system? C) 8 | back 80 B |
front 81 20) A black guinea pig crossed with an albino guinea pig produced
twelve black offspring. When the albino was crossed with a second
black animal, six blacks and six albinos were obtained. What is the
best explanation for this genetic situation? B) Albino is dominant; black is incompletely dominant. C) Albino and black are codominant. | back 81 A |
front 82 22) When Mendel crossed yellow-seeded and green-seeded pea plants, all the offspring were yellow seeded. When he took these F1 yellow-seeded plants and crossed them to green-seeded plants, what genotypic ratio was expected? A) 1:2:1 D) 1:1:1:1 | back 82 C |
front 83 23) Black fur in mice (B) is dominant to brown fur (b). Short tails
(T) are dominant to long tails (t). What fraction of the progeny of
crosses BbTt × BBtt will be expected to have black fur and long
tails? B) 3/8 | back 83 C |
front 84 25) In the cross AaBbCc × AaBbCc, what is the probability of producing the genotype AABBCC? A) 1/4 D) 1/64 | back 84 D |
front 85 26) Given the parents AABBCc × AabbCc, assume simple dominance for
each trait and independent assortment. What proportion of the progeny
will be expected to phenotypically resemble the first parent with
genotype AABBCc? B) 3/4 | back 85 B |
front 86 27) Which of the following is the best statement of the use of the addition rule of probability? A) the probability that two or more independent events will both
occur D) the likelihood that a trait is due to two or more meiotic events | back 86 B |
front 87 28) Which of the following calculations require that you utilize the
addition rule? | back 87 D |
front 88 29) Two true-breeding stocks of pea plants are crossed. One parent has red, axial flowers and the other has white, terminal flowers; all F1 individuals have red, axial flowers. The genes for flower color and location assort independently. Among the F2 offspring, what is the probability of plants with white axial flowers? A) 9/16 | back 88 C |
front 89 31) Phenylketonuria is an inherited disease caused by a recessive
autosomal allele. If a woman and her husband are both carriers, what
is the probability that their first child will be a phenotypically
normal girl? B) 1/16 | back 89 D |
front 90 32) Assuming independent assortment for all gene pairs, what is the
probability that the following parents, AABbCc × AaBbCc, will produce
an AaBbCc offspring? C) 1/8 | back 90 C |
front 91 33) Suppose two AaBbCc individuals are mated. Assuming that the genes
are not linked, what fraction of the offspring are expected to be
homozygous recessive for the three traits? C) 1/16 | back 91 D |
front 92 34) In cattle, roan coat color (mixed red and white hairs) occurs in
the heterozygous (Rr) offspring of red (RR) and white (rr)
homozygotes. Which of the following crosses would produce offspring in
the ratio of 1 red:2 roan:1 white? B) roan × roan | back 92 B |
front 93 35) Which of the following describes the ability of a single allele
to have multiple phenotypic effects? C) pleiotropy | back 93 C |
front 94 36) Which of the following is an example of polygenic inheritance? A) pink flowers in snapdragons D) skin pigmentation in humans | back 94 D |
front 95 38) Which of the following provides an example of epistasis? | back 95 B |
front 96 39) Radish flowers may be red, purple, or white. A cross between a red-flowered plant and a white-flowered plant yields all-purple offspring. The part of the radish we eat may be oval or long, with long being the dominant trait. If true-breeding red long radishes are crossed with true- breeding white oval radishes, the F1 will be expected to be which of the following? A) red and long | back 96 C |
front 97 42) Gene S controls the sharpness of spines in a type of cactus.
Cactuses with the dominant allele, S, have sharp spines, whereas
homozygous recessive ss cactuses have dull spines. At the same time, a
second gene, N, determines whether or not cactuses have spines.
Homozygous recessive nn cactuses have no spines at all. The
relationship between genes S and N is an example of _____. | back 97 B |
front 98 43) Gene S controls the sharpness of spines in a type of cactus.
Cactuses with the dominant allele, S, have sharp spines, whereas
homozygous recessive ss cactuses have dull spines. At the same time, a
second gene, N, determines whether or not cactuses have spines.
Homozygous recessive nn cactuses have no spines at all. A cross
between a true-breeding sharp-spined cactus and a spineless cactus
would produce_____. | back 98 A |
front 99 44) Gene S controls the sharpness of spines in a type of cactus.
Cactuses with the dominant allele, S, have sharp spines, whereas
homozygous recessive ss cactuses have dull spines. At the same time, a
second gene, N, determines whether or not cactuses have spines.
Homozygous recessive nn cactuses have no spines at all. If doubly
heterozygous SsNn cactuses were allowed to self-pollinate, the F2
would segregate in which of the following ratios? | back 99 D |
front 100 45) Feather color in budgies is determined by two different genes, Y and B, one for pigment on the outside and one for the inside of the feather. YYBB, YyBB, or YYBb is green; yyBB or yyBb is blue; YYbb or Yybb is yellow; and yybb is white. A blue budgie is crossed with a white budgie. Which of the following results is NOT possible? A) green offspring only | back 100 D |