The tubelike digestive system canal that extends from the mouth to the anus is known as the__________canal or the _________tract?
Alimentary canal or gastrointestinal tract
Differentiate between the colon and the large intestine?
Large intestine extends from the ileocecal valve to the anus. Colon is part of the large intestine and is divided into ascending, descending, and Transverse (sigmoid) colon.
What is the role of the gallbladder?
Stores bile
Why is the liver so dark red in the living animal?
High amount of blood that circulates through the liver
What is the function of Kupffer cells of the liver?
Sinusoid walls; remove debris such as bacteria or won-out blood cells from the blood.
List the three characteristics of enzymes?
specificity
temperature specific
pH specific
Waves of muscular contractions that propel the contents of the digestive tract from one point to another are called?
Peristalsis
The esophagus is a part of the ______, while the pancreas is considered a(n) _______ when it comes to the digestive system?
alimentary canal... accessory digestive organ
The correct sequence for the layers in the walls of the alimentary canal from innermost to outermost is the…?
mucosa, submucosa, muscle layer, serosa
- The majority of absorption occurs in the ________?
small intestine
List the four layers of the wall of the alimentary canal in the appropriate order from innermost to outermost?
mucosa, submucosa, muscularis externa and serosa
List accessory organs of digestive system?
Teeth, tongue, gallbladder, salivary glands, liver, pancreas
The _________ are double layers of peritoneum that extend from the body wall to the digestive viscera and help anchor them in place?
mesenteries
List functions of the stomach?
Storage, mechanical breakdown, disruption of chemical bonds, production of intrinsic factor
Which organ is responsible for dehydration and compaction of indigestible materials?
large intestine
What is the function(s) of HCl (hydrochloric acid)?
Kill most bacteria, denature proteins, inactivate food enzymes, breakdown plant cells and connective tissue in meat, activate pepsinogen to pepsin
Where are the motor neurons that control smooth muscle contraction and glandular secretions of the GI tract located?
Myenteric Plexus
Chemical digestion is initiated in the _________?
mouth
Why does your mouth suddenly “go dry” when you are about to deliver a presentation to a large crowd?
sympathetic activity inhibits salivation
List functions of digestive system?
Releasing nutrients from food, and absorbing those nutrients
List functions of saliva?
-provide lubrication
-help to control bacterial populations in the mouth
-bind food together àmoistening
-begin chemical digestion of carbohydrates
-enzyme salivary amylase breaks polysaccharides into disaccharides
What is a possible side effect of weakening of the cardiac sphincter?
acid reflux into the esophagus
The stomach is able to expand nearly 100 times its empty volume partly due to _________ in its walls?
rugae
A patient with a low RBC count receives vitamin B12 injections every 2 weeks. Why injection not orally?
parietal cells in this patient's stomach have ceased producing intrinsic factor
Why is pepsin inactive when tested at pH 7?
pepsin's activity is specific to the stomach's pH of 1.5-3.5
Digestion of which of the following (proteins, carbohydrate, fats) might be inhibited if a patient chronically consumes an antacid?
protein
When your stomach growls in response to an ad on TV for food, the _________ phase of gastric secretion is initiated?
cephalic
The parietal cells of gastric glands secrete?
Hydrochloric acid
The ______ cells are responsible for HCl production?
parietal
What is the primary stimulus for intestinal gland secretion of secretin?
an acidic content
distension of the intestinal wall
What is the primary stimulus for intestinal gland secretion of Cholecystokinin (CCK)?
fats.
______ stimulates the gallbladder to contract?
CCK
Salivary amylase digests…?
Starch
Cirrhosis of the liver would most severely impact
digestion of _________? why?
lipids
In terms of absorption, the large intestine’s greatest contribution is?
absorption of water.
List organs of alimentary canal from mouth to anus?
mouth, pharynx, esophagus, stomach, small intestine, large intestine, and anus.
Gastric pit are?
Pockets in the lining of the stomach that contain secretory cells
Propulsion of food along the digestive tract is achieved by wave like muscle contraction called?
Peristalsis
Pockets in the lining of the stomach that contain secretory cells are…?
Gastric pits
Peristalsis is?
Waves of muscular contractions that propel the contents of the digestive tract from one point to another
Which histological layer of the alimentary canal is also known as the visceral peritoneum?
Serosa
The membrane that lines the body wall of the abdominal cavity is the?
parietal peritoneum.
Saliva is composed mainly of…….?
water
The prominent ridges in the lining of the empty stomach are called?
rugae
An intestinal hormone that stimulates the gall bladder to release bile is?
choleceystokinin
An intestinal hormone that stimulates the pancreas to release bicarbonate is?
secretin
The gastric cells that secrete pepsinogen are the….?
Chief cells
Most of the digestive enzymes found in the small intestine are secreted by which accessory organ of digestive system?
Pancreas
Parietal cells of stomach secrete?
secrete hydrochloric acid (HCl) and intrinsic factor
The pylorus empties into the?
duodenum
Why absorption cannot occur in stomach?
Food is too large and need to be small. Need to be broken down to its monomers.
The fingerlike projections of the intestinal mucosa are called?
villi
Which region of the stomach does the esophagus connect to?
cardia
Which substance secreted by the pancreas helps neutralize chyme?
Bicarbonate
Which hormone triggers the release of enzyme-rich pancreatic juice and constriction of gall bladder to eject bile?
Cck hormone
Mary had her stomach mostly removed to try to overcome obesity. As a result you would expect Mary to be at risk for _________ . Why?
pernicious anemia
G cells of the stomach secrete?
gastrin.
List functions of large intestine?
-secretion = mucus
-absorption = water and electrolytes
-storage = feces
Openings into gastric glands are called?
Gastric Pit
Gastric pits are?
Openings into gastric glands
The activities of the digestive system are regulated by?
intrinsic nerve plexuses.
parasympathetic and sympathetic
neurons.
hormones.
the contents of the digestive tract.
Amylase allows us to digest?
Carbohydrates
Micelles are formed during the absorption of which nutrient?
Fatty acids (Fats)
The portion of the small intestine that is attached to the pylorus of the stomach is the…?
Duodenum
Intrinsic factor is produced in the stomach and is necessary for the absorption of?
Vitamin B12
List functions of mesenteries?
Stabilizes the organs, provide pathway for bloodvessels and lymphathic vessels, prevent your intestine from being twisted or tangled
Which age-related changes in the digestive system are the results of decreased smooth muscle tone?
Weaker peristaltic contractions and decrease in motility.
Presence of Hemorrhoids and esophageal reflux.
Chief cells of stomach secrete?
Zymogen-pepsinogen, a precursor to pepsin
The four major layers of the GI tract are ______?
Mucosa, Submucosa, Muscularis Externa, Serosa/Adventitia
The major histological differences between the large intestine and small intestine are that the large intestine ______?
Lacks villi, has abundant goblet cells, and deeper intestinal glands.
How do most chylomicrons enter the lymphatic system?
Through Lacteals
All of the enzymes that digest protein are secreted in an …. Form? Why?
secreted in an inactive form.
Where in the human body will chemical digestion begin?
In the Oral Cavity
Where are the motor neurons that control smooth muscle contraction and glandular secretions of the GI tract located?
In the Myenteric Plexus
Heartburn is usually caused by the effects of gastric juice on the?
esophagus
The portion of stomach that connects to the esophagus is the….?
Cardia
The portion of stomach that connects to the duodenum …..?
pylorus
How do the roles of pepsinogen and HCI interact in the stomach?
HCl is necessary for the conversion of pepsinogen to pepsin.
Secretion of cholecystokinin from the intestinal wall is stimulated by?
protein and fat in the small intestine.
What effect(s) does the secretion of CCK have on a fatty meal’s entrance to the duodenum?
Inhibits secretion of gastric acids and enzymes, slowing gastric emptying
The myenteric plexus is….?
The myenteric plexus, otherwise known as Auerbach's plexus, is the poriton of the enteric nervous system located between the outer longitudinal and inner circular smooth muscle layers of the wall of the GI tract
How many pairs of salivary gland are there in human oral cavity?
3 pairs
The alimentary canal extends, in its entirety, from the …. to the……?
- mouth
- anus
The enzymes of the digestive system are classified as hydrolases. What does this mean?
hydrolyses break down organic food molecules by adding water to the molecular bonds, thus cleaving the bonds between the subunits or monomers
Fill in the following chart about the various digestive system enzymes?
...
Assume you have been chewing a piece of bread for 5 or 6 minutes. How would you expect its taste to change during this interval?
the bread would begin to taste sweet because starch is broken down to glucose by amylase.
Gallstones are usually composed of?
Cholesterol
Using a flowchart, trace the pathway of a chicken sandwich (chicken = protein and fat; bread = starch) from the mouth to the site of absorption of its breakdown products, noting where digestion occurs and what specific enzymes are involved and what are the end products at that site.
...
Name the end products of digestion for the following types of foods
Polymer (product before digestion) Monomer or the end product after digestion
Proteins
Carbohydrates
Fats
...
Various types of glands form a part of the alimentary tube wall and release their secretions into it. Match the glands or their product listed in the key to the appropriate description bellow.
Key: salivary glands, gall bladder, liver, pancreas, duodenal glands, Chief cells , gastric glands, HCl (hydrochloric acid)
a. produce(s) mucus; found in the submucosa of the small intestine?
b. produce(s) a product containing amylase that begins starch breakdown in the mouth?
c. stores and modifies bile?
d. produce(s) a whole spectrum of enzymes and an alkaline fluid that is secreted into the duodenum?
e. converts pepsingogen to pepsin?
f. produce(s) bile that it secretes into the duodenum via the bile duct?
g. produce(s) HCl and pepsinogen?
h. produces enzyme that initiates digestion of protein in the stomach?
- duodenal glands
- salivary glands
- Gall bladder
- pancreas
- HCl
- liver
- gastric glands
- Chief Cells
Bile salts function like detergents in that they ___________ fat globules?
emulsify
List the correct sequence for the digestion of lipids?
Immunsafide by the bile then -> hydrolyzed
The roof of the oral cavity is formed by the?
Soft and hard pallet
Functions of the tongue include?
-mechcanical processing (mixing food)
-manipulation to assist chewing and swallowing
-sensory analysis
-secretion of mucus and enzyme (lingual lipase)
Some of the digestive organs have groups of secretory cells that release hormones into the blood.
These hormones exert an effect on the digestive process by acting on other cells, glands or structures and causing them to release digestive enzymes, cause contraction to eject bile, or increase the motility of the digestive tract. For each hormone below, note the organ producing the hormone and its effects on the digestive process. Include the target organs affected.
Hormone Produced by Target organ(s) and effects
Secretin
Gastrin
Cholecystokinin
(CCK)
...
Use the following keys to match them with appropriate definitions bellow:
Key: villi, tongue,
mesentery, oral cavity, stomach, esophagus,
pharynx, microvilli, rugae, ileocecal valve, anus,
small
intestine, pyloric valve, large intestine, stomach
- structure that suspends the small intestine from the posterior body wall?
- folds that allow stomach to stretch?
- fingerlike extensions of the intestinal mucosa that increase the surface area for absorption?
- regions that break down foodstuffs mechanically?
- mobile organ that manipulates food in the mouth and initiates swallowing?
- conduit for both air and food?
- the “gullet”; no digestive/absorptive function?
- folds of the gastric mucosa?
- valve at the junction of the small and large intestines
- projections of the plasma membrane of a mucosal epithelial cell?
- absorbs water and forms feces?
- primary region of food absorption?
- initiates protein digestion?
- valve controlling food movement from the stomach into the duodenum?
- principal site for the synthesis of vitamin K by microorganisms?
- region containing two sphincters through which feces are expelled from the body?
- Mesentery
- d
- Villi
- oral cavity, stomach
- Tongue
- pharynx
- esophagus
- rugae
- ileocecal valve
- microvilli
- large intestine
- small intestine
- stomach
- pyloric valve
- large intestine
- anus
use the diagram bellow to answer the following questions:
- What is the function of the structure labeled "6"?
- Identify the stomach region labeled "12"?
- Which structure helps the stomach to stretch as it fills with food?
- Identify the structure labeled "7”?
- Pyloric Sphincter
- Regulates Passageway into the duodenum
- Fundus
- d
- Pylorus