1) The smallest cell structure that would most likely be visible with
a standard (not super- resolution) research-grade light microscope is
a _____.
A) mitochondrion
B) microtubule
C) ribosome
D) microfilament
Answer: A
2) The advantage of light microscopy over electron microscopy is that
_____.
A) light microscopy provides for higher magnification
than electron microscopy
B) light microscopy provides for higher resolving power than
electron microscopy C) light microscopy allows one to view dynamic
processes in living cells
D) light microscopy provides higher
contrast than electron microscopy
Answer: C
3) In the fractionation of homogenized cells using centrifugation,
the primary factor that determines whether a specific cellular
component ends up in the supernatant or the pellet is the _____.
A) relative solubility of the component
B) size and weight of
the component
C) percentage of carbohydrates in the
component
D) presence or absence of lipids in the component
Answer: B
4) What is the reason that a modern transmission electron microscope
(TEM) can resolve biological images to the subnanometer level, as
opposed to tens of nanometers achievable for the best super-resolution
light microscope?
A) The focal length of the electron microscope
is significantly longer.
B) Contrast is enhanced by staining
with atoms of heavy metal.
C) Electron beams have much shorter
wavelengths than visible light.
D) The electron microscope has a
much greater ratio of image size to real size.
Answer: C
5) What technique would be most appropriate to use to observe the
movements of condensed chromosomes during cell division?
A)
standard light microscopy
B) scanning electron microscopy
C) transmission electron microscopy
Answer: A
6) A newspaper ad for a local toy store indicates that an inexpensive
toy microscope available for a small child is able to magnify
specimens nearly as much as the more costly microscope available in
your college lab. What is the primary reason for the price
difference?
A) The toy microscope does not have the same fine
control for focus of the specimen.
B) The toy microscope magnifies a good deal, but has low resolution
and therefore poor quality images.
C) The college microscope
produces greater contrast in the specimens.
D) The toy
microscope usually uses a different wavelength of light source.
Answer: B
7) All of the following are part of a prokaryotic cell EXCEPT _____.
A) a cell wall
B) a plasma membrane
C) ribosomes
D) an endoplasmic reticulum
Answer: D
8) Cell size is limited by _____.
A) the number of proteins
within the plasma membrane
B) the surface area of mitochondria in the cytoplasm
C) surface to volume ratios
D) the size of the endomembrane system
Answer: C
9) Which of the following is a major difference between prokaryotic cells and eukaryotic cells?
A) Prokaryotes have cells while eukaryotes do not.
B)
Eukaryotic cells have more intracellular organelles than
prokaryotes.
C) Prokaryotes are not able to carry out aerobic
respiration, relying instead on anaerobic metabolism.
D) Prokaryotes are generally larger than eukaryotes.
Answer: B
10) You have a cube of modeling clay in your hands. Which of the
following changes to the shape of this cube of clay will decrease its
surface area relative to its volume?
A) Pinch the edges of the
cube into small folds.
B) Flatten the cube into a pancake shape.
C) Round the clay up into a sphere.
D) Stretch the cube into a
long, shoebox shape.
Answer: C
11) Prokaryotes are classified as belonging to two different domains. What are the domains?
A) Bacteria and Eukarya
B) Bacteria and Archaea
C)
Archaea and Protista
D) Bacteria and Protista
Answer: B
12) Which structure is common to plant and animal cells?
A) chloroplast
B) central vacuole
C) mitochondrion
D) centriole
Answer: C
13) Which of the following is present in a prokaryotic cell?
A) mitochondrion
B) ribosome
C) chloroplast
D) ER
Answer: B
14) In a bacterium, we will find DNA in _____.
A) a membrane-enclosed nucleus
B) mitochondria
C) the nucleoid
D) ribosomes
Answer: C
15) Which organelle or structure is absent in plant cells?
A) mitochondria
B) microtubules
C) centrosomes
D) peroxisomes
Answer: C
16) What is the function of the nuclear pore complex found in
eukaryotes?
A) It regulates the movement of proteins and RNAs
into and out of the nucleus.
B) It synthesizes the proteins
required to copy DNA and make mRNA.
C) It selectively transports
molecules out of the nucleus, but prevents all inbound molecules from
entering the nucleus.
D) It assembles ribosomes from raw
materials that are synthesized in the nucleus.
Answer: A
17) Which of the following macromolecules leaves the nucleus of a
eukaryotic cell through pores in the nuclear membrane?
A)
DNA
B) amino acids
C) mRNA
D) phospholipids
Answer: C
18) Which of the following statements correctly describes some aspect
of protein secretion from prokaryotic cells?
A) Prokaryotes
cannot secrete proteins because they lack an endomembrane
system.
B) The mechanism of protein secretion in prokaryotes is
probably the same as that in eukaryotes.
C) Proteins secreted by prokaryotes are synthesized on ribosomes bound to the cytoplasmic surface of the plasma membrane.
D) Prokaryotes cannot secrete proteins because they lack ribosomes.
Answer: C
19) Large numbers of ribosomes are present in cells that specialize
in producing which of the following molecules?
A) lipids
B) glycogen
C) proteins
D) nucleic acids
Answer: C
20) The nuclear lamina is an array of filaments on the inner side of
the nuclear membrane. If a method were found that could cause the
lamina to fall into disarray, what would you most likely expect to be
the immediate consequence?
A) the loss of all nuclear function
B) the inability of the nucleus to divide during cell division
C) a change in the shape of the nucleus
D) failure of
chromosomes to carry genetic information
Answer: C
21) A cell with a predominance of free ribosomes is most likely _____.
A) primarily producing proteins for secretion
B) primarily
producing proteins in the cytosol
C) constructing an extensive
cell wall or extracellular matrix
D) enlarging its vacuole
Answer: B
22) Which organelle often takes up much of the volume of a plant cell?
A) lysosome
B) vacuole
C) Golgi apparatus
D) peroxisome
Answer: B
23) A cell with an extensive area of smooth endoplasmic reticulum is specialized to _____.
A) play a role in storage
B) synthesize large quantities of
lipids
C) actively export protein molecules
D) import and export protein molecules
Answer: B
24) Which structure is NOT part of the endomembrane system?
A) nuclear envelope
B) chloroplast
C) Golgi apparatus
D) plasma membrane
Answer: B
25) The Golgi apparatus has a polarity, or sidedness, to its
structure and function. Which of the following statements correctly
describes this polarity?
A) Transport vesicles fuse with one
side of the Golgi and leave from the opposite side.
B) Proteins
in the membrane of the Golgi may be sorted and modified as they move
from one side of the Golgi to the other.
C) Lipids in the membrane of the Golgi may be sorted and modified as
they move from one side of the Golgi to the other.
D) All of the
listed responses correctly describe polarity characteristics of the
Golgi function.
Answer: D
26) The difference in lipid and protein composition between the
membranes of the endomembrane system is largely determined by the
_____.
A) transportation of membrane lipids among the membranes
of the endomembrane system by small membrane vesicles
B)
function of the Golgi apparatus in sorting and directing membrane
components
C) modification of the membrane components once they
reach their final destination
D) synthesis of different lipids
and proteins in each of the organelles of the endomembrane system
Answer: B
27) Which structure is the site of the synthesis of proteins that may be exported from the cell?
A) rough ER
B) plasmodesmata
C) Golgi vesicles
D) free cytoplasmic ribosomes
Answer: A
28) Tay-Sachs disease is a human genetic abnormality that results in
cells accumulating and becoming clogged with very large, complex,
undigested lipids. Which cellular organelle must be involved in this
condition?
A) the endoplasmic reticulum
B) the Golgi apparatus
C) the lysosome
D) mitochondrion
Answer: C
29) The liver is involved in detoxification of many poisons and
drugs. Which of the following structures is primarily involved in this
process and, therefore, abundant in liver cells?
A) rough
ER
B) smooth ER
C) Golgi apparatus
D) nuclear envelope
Answer: B
30) Which of the following produces and modifies polysaccharides that will be secreted?
A) lysosome
B) mitochondrion
C) Golgi apparatus
D) peroxisome
Answer: C
31) What is the most likely pathway taken by a newly synthesized
protein that will be secreted by a cell?
A) ER → Golgi →
nucleus
B) Golgi → ER → lysosome
C) ER → Golgi → vesicles that fuse with plasma membrane
D) ER
→ lysosomes → vesicles that fuse with plasma membrane
Answer: C
32) Asbestos is a material that was once used extensively in construction. One risk from working in a building that contains asbestos is the development of asbestosis caused by the inhalation of asbestos fibers. Cells will phagocytize asbestos, but are not able to degrade it. As a result, asbestos fibers accumulate in _____.
A) mitochondria
B) ribosomes
C) peroxisomes
D) lysosomes
Answer: D
33) Which of the following is NOT true? Both chloroplasts and mitochondria _____.
A) have their own DNA
B) have multiple membranes
C) are
part of the endomembrane system
D) are capable of reproducing themselves
Answer: C
34) Which organelle is the primary site of ATP synthesis in eukaryotic cells?
A) lysosome
B) mitochondrion
C) Golgi apparatus
D) peroxisome
Answer: B
35) Thylakoids, DNA, and ribosomes are all components found in _____.
A) chloroplasts
B) mitochondria
C) lysosomes
D) nuclei
Answer: A
36) In a plant cell, DNA may be found _____.
A) only in the
nucleus
B) only in the nucleus and chloroplasts
C) in the
nucleus, mitochondria, and chloroplasts
D) in the nucleus,
mitochondria, chloroplasts, and peroxisomes
Answer: C
37) In a liver cell detoxifying alcohol and some other poisons, the
enzymes of the peroxisome remove hydrogen from these molecules and
_____.
A) combine the hydrogen with water molecules to generate
hydrogen peroxide
B) use the hydrogen to break down hydrogen peroxide
C) transfer the hydrogen to the mitochondria
D) transfer the
hydrogen to oxygen molecules to generate hydrogen peroxide
Answer: D
38) The evolution of eukaryotic cells most likely involved
_____.
A) endosymbiosis of an aerobic bacterium in a larger host
cell—the endosymbiont evolved into mitochondria
B) anaerobic
archaea taking up residence inside a larger bacterial host cell to
escape toxic oxygen—the anaerobic bacterium evolved into
chloroplasts
C) an endosymbiotic fungal cell evolving into the
nucleus
D) acquisition of an endomembrane system and subsequent
evolution of mitochondria from a portion of the Golgi
Answer: A
39) Where are proteins produced other than on ribosomes free in the
cytosol or ribosomes attached to the ER?
A) in the extracellular
matrix
B) in the Golgi apparatus
C) in mitochondria
D) in the nucleolus
Answer: C
40) Suppose a cell has the following molecules and structures:
enzymes, DNA, ribosomes, plasma membrane, and mitochondria. It could
be a cell from _____.
A) a bacterium
B) an animal but not
a plant
C) nearly any eukaryotic organism
D) a plant but not an animal
Answer: C
41) Cyanide binds with at least one molecule involved in producing
ATP. If a cell is exposed to cyanide, most of the cyanide will be
found within the _____.
A) mitochondria
B) peroxisomes
C) lysosomes
D) endoplasmic reticulum
Answer: A
42) Suppose a young boy is always tired and fatigued, suffering from
a metabolic disease. Which of the following organelles is most likely
involved in this disease?
A) lysosomes
B) Golgi apparatus
C) ribosomes
D) mitochondria
Answer: D
43) Motor proteins provide for molecular motion in cells by
interacting with what types of cellular structures?
A) membrane
proteins of the inner nuclear envelope
B) free ribosomes and
ribosomes attached to the ER
C) components of the cytoskeleton
D) cellulose fibers in the
cell wall
Answer: C
44) Which of the following contain the 9 + 2 arrangement of
microtubules, consisting of nine doublets of microtubules surrounding
a pair of single microtubules?
A) motile cilia and primary
(nonmotile) cilia
B) flagella and motile cilia
C) basal bodies and primary (nonmotile) cilia
D) centrioles
and basal bodies
Answer: B
45) Vinblastine, a drug that inhibits microtubule polymerization, is
used to treat some forms of cancer. Cancer cells given vinblastine
would be unable to _____.
A) form cleavage furrows during cell
division
B) migrate by amoeboid movement
C) separate chromosomes during cell division D) maintain the shape of the nucleus
Answer: C
46) Amoebae move by crawling over a surface (cell crawling), which
involves _____.
A) growth of actin filaments to form bulges in
the plasma membrane
B) setting up microtubule extensions that
vesicles can follow in the movement of cytoplasm
C) reinforcing the pseudopod with intermediate filaments
D)
cytoplasmic streaming
Answer: A
47) Researchers tried to explain how vesicular transport occurs in
cells by attempting to assemble the transport components. They set up
microtubular tracks along which vesicles could be transported, and
they added vesicles and ATP (because they knew the transport process
requires energy). Yet, when they put everything together, there was no
movement or transport of vesicles. What were they missing?
A) an
axon
B) contractile microfilaments
C) endoplasmic
reticulum
D) motor proteins
Answer: D
48) Cilia and flagella bend because of _____.
A) conformational
changes in ATP that thrust microtubules laterally
B) a motor protein called radial spokes
C) the quick inward
movements of water by osmosis.
D) a motor protein called dynein
Answer: D
49) Spherocytosis is a human blood disorder associated with a
defective cytoskeletal protein in the red blood cells (RBCs). What do
you suspect is the consequence of such a defect?
A) abnormally
shaped RBCs
B) an insufficient supply of ATP in the RBCs
C) an insufficient supply of oxygen-transporting proteins in the RBCs
D) adherence of RBCs to blood vessel walls, causing plaque formation
Answer: A
50) Cytochalasin D is a drug that prevents actin polymerization. A
cell treated with cytochalasin D will still be able to _____.
A)
divide in two
B) contract muscle fibers
C) extend pseudopodia
D) move vesicles within a cell
Answer: D
51) Cells require which of the following to form cilia or flagella?
A) tubulin
B) laminin
C) actin
D) intermediate filaments
Answer: A
52) Which of the following statements about the cytoskeleton is
true?
A) The cytoskeleton of eukaryotes is a static structure
most resembling scaffolding used at construction sites.
B)
Although microtubules are common within a cell, actin filaments are
rarely found outside of the nucleus.
C) Movement of cilia and
flagella is the result of motor proteins causing microtubules to move
relative to each other.
D) Chemicals that block the assembly of
the cytoskeleton would have little effect on a cell's response to
external stimuli.
Answer: C
53) The cell walls of bacteria, fungi, and plant cells and the
extracellular matrix of animal cells are all external to the plasma
membrane. Which of the following is a characteristic common to all of
these extracellular structures?
A) They must block water and
small molecules to regulate the exchange of matter and energy with
their environment.
B) They must provide a rigid structure that maintains an appropriate
ratio of cell surface area to volume.
C) They are constructed of
polymers that are synthesized in the cytoplasm and then transported
out of the cell.
D) They are composed of a mixture of lipids and nucleotides.
Answer: C
54) A mutation that disrupts the ability of an animal cell to add
polysaccharide modifications to proteins would most likely cause
defects in its _____.
A) nuclear matrix and extracellular
matrix
B) mitochondria and Golgi apparatus
C) Golgi apparatus and extracellular matrix
D) nuclear pores and secretory vesicles
Answer: C
55) The extracellular matrix is thought to participate in the regulation of animal cell behavior by communicating information from the outside to the inside of the cell via which of the following?
A) gap junctions
B) the nucleus
C) DNA and RNA
D) integrins
Answer: D
56) Plasmodesmata in plant cells are most similar in function to
which of the following structures in animal cells?
A)
desmosomes
B) gap junctions
C) extracellular matrix
D) tight junctions
Answer: B
57) Ions can travel directly from the cytoplasm of one animal cell to
the cytoplasm of an adjacent cell through _____.
A)
plasmodesmata
B) tight junctions
C) desmosomes
D) gap junctions
Answer: D
58) In plant cells, the middle lamella _____.
A) allows
adjacent cells to adhere to one another
B) prevents dehydration
of adjacent cells
C) maintains the plant's circulatory
system
D) allows for gas and nutrient exchange among adjacent cells
Answer: A
59) Where would you expect to find tight junctions?
A) in the
epithelium of an animal's stomach
B) between the smooth
endoplasmic reticulum and the rough endoplasmic reticulum
C) between plant cells in a woody plant
D) in the plasma
membrane of prokaryotes
Answer: A
60) H. V. Wilson worked with sponges to gain some insight into
exactly what was responsible for holding adjacent cells together. He
exposed two species of differently pigmented sponges to a chemical
that disrupted the cell-cell interaction (cell junctions), and the
cells of the sponges dissociated. Wilson then mixed the cells of the
two species and removed the chemical that caused the cells to
dissociate. Wilson found that the sponges reassembled into two
separate species. The cells from one species did not interact or form
associations with the cells of the other species. How do you explain
the results of Wilson's experiments?
A) The two species of
sponge had different enzymes that functioned in the reassembly process.
B) The molecules responsible for cell-cell adhesion (cell junctions)
were irreversibly destroyed during the experiment.
C) The
molecules responsible for cell-cell adhesion (cell junctions) differed
between the two species of sponge.
D) One cell functioned as the
nucleus for each organism, thereby attracting only cells of the same pigment.
Answer: C
61) Gaucher disease is the most common of lipid storage diseases in humans. It is caused by a deficiency of an enzyme necessary for lipid metabolism. This leads to a collection of fatty material in organs of the body including the spleen, liver, kidneys, lungs, brain, and bone marrow.
Using your knowledge of the structure of eukaryotic cells, identify
the statement below that best explains how internal membranes and the
organelles of cells would be involved in Gaucher disease.
A) The
mitochondria are most likely defective and do not produce adequate
amounts of ATP needed for cellular respiration.
B) The rough endoplasmic reticulum contains too many ribosomes which
results in an overproduction of the enzyme involved in carbohydrate
catalysis.
C) The lysosomes lack sufficient amounts of enzymes
necessary for the metabolism of lipids.
D) The Golgi apparatus produces vesicles with faulty membranes that leak their contents into the cytoplasm of the cell.
Answer: C