What is the most abundant intracellular cation?
Na+
HPO42-
K+
Cl-
K+
What is the most abundant intracellular anion?
HPO42-
K+
Na+
Cl-
HPO4 2-
Which of the following regulates the secretion of K+ into the filtrate?
antidiuretic hormone
atrial natriuretic peptide
(ANP)
parathyroid hormone (PTH)
aldosterone
aldosterone
PTH (parathyroid hormone) acts on the __________ to __________ Ca2+
reabsorption.
liver; decrease
bones; decrease
DCT;
increase
large intestine; increase
DCT; increase
Which of the following does NOT serve as a source of acids in the
body?
aerobic breakdown of glucose
fat metabolism
CO2
in the blood
ingested foods
aerobic breakdown of glucose
The primary buffer of the extracellular fluid (ECF) is the
__________.
phosphate buffer system
protein buffer
system
sodium-potassium buffer system
bicarbonate buffer system
bicarbonate buffer system
Starvation would cause which of the following acid-base conditions?
Also, determine what type of compensation (metabolic or respiratory)
there would be.
metabolic alkalosis with respiratory
compensation
respiratory alkalosis with metabolic
compensation
respiratory acidosis with metabolic
compensation
metabolic acidosis with respiratory compensation
metabolic acidosis with respiratory compensation
A patient is admitted to the hospital with the following plasma
values: pH = 7.2, pCO2 = 55 mmHg, and HCO3¯ = 30 mEq/L. What is the
acid base imbalance?
metabolic acidosis with respiratory
compensation
respiratory alkalosis with metabolic
compensation
respiratory acidosis with metabolic
compensation
metabolic alkalosis with respiratory compensation
respiratory acidosis with metabolic compensation
A patient is admitted to the hospital with the following plasma
values: pH = 7.5, pCO2 = 45 mmHg, and HCO3¯ = 30 mEq/L. What is the
acid-base imbalance?
metabolic alkalosis with no
compensation
respiratory acidosis with metabolic
compensation
metabolic alkalosis with respiratory
compensation
respiratory alkalosis with metabolic compensation
metabolic alkalosis with no compensation
A patient is admitted to the hospital with the following plasma
values: pH = 7.2, pCO2 = 25 mmHg, and HCO3¯ = 18 mEq/L. What is the
acid base imbalance?
metabolic acidosis with respiratory
compensation
respiratory acidosis with metabolic
compensation
metabolic alkalosis with respiratory
compensation
metabolic acidosis with no compensation
metabolic acidosis with respiratory compensation
Diarrhea can lead to which acid/base disturbance? Assuming
compensation, would it be a metabolic or respiratory
compensation?
metabolic acidosis with respiratory
compensation
respiratory acidosis with metabolic
compensation
respiratory alkalosis with metabolic
compensation
metabolic alkalosis with respiratory compensation
metabolic acidosis with respiratory compensation
Emphysema can lead to which acid/base disturbance? What would be the
compensation?
respiratory alkalosis; kidneys will retain more H+
and excrete HCO3
metabolic acidosis; hypoventilation by the
lungs
respiratory acidosis; kidneys will retain more HCO3 and
excrete H+
respiratory acidosis; hyperventilation
respiratory acidosis; kidneys will retain more HCO3 and excrete H+
Of the three buffering mechanisms in the body, which is the
strongest?
respiratory system
chemical buffer
system
renal system
renal system
The bicarbonate buffer system is one of the chemical buffer systems
of the body. How would the bicarbonate buffer system work if sodium
hydroxide were added to a solution?
A hydrogen on carbonic acid
would dissociate and join the hydroxyl group on the base to form water
and sodium bicarbonate.
The hydrogen ion would attach to carbonic
acid.
The hydrogen ion would attach to bicarbonate (HCO3) to form
carbonic acid (H2CO3).
A hydrogen on carbonic acid would dissociate and join the hydroxyl group on the base to form water and sodium bicarbonate.
The respiratory system is one of the three systems that regulate
acid-base balance in the body. How does it work to decrease an
acidosis?
Carbonic acid is converted to bicarbonate, which then
buffers the acid.
Carbonic acid is converted to bicarbonate and
hydrogen ions.
Carbonic acid converts a strong acid to a weak
acid, thus decreasing acidity.
Carbonic acid is broken down into
water and CO2; the CO2 is then exhaled.
Carbonic acid is broken down into water and CO2; the CO2 is then exhaled.
In a respiratory acidosis the kidney would do which of the
following?
The kidney will reabsorb both bicarbonate and hydrogen
ions. When it reabsorbs the hydrogen ion, it also generates more
bicarbonate ions.
The kidney would increase excretion of both
bicarbonate and hydrogen ions.
The kidney would reabsorb
bicarbonate and secrete hydrogen ions.
The kidney would reabsorb bicarbonate and secrete hydrogen ions.
Ingesting too much antacid would cause which of the following
acid-base disturbances?
respiratory alkalosis
metabolic
alkalosis
metabolic acidosis
respiratory acidosis
metabolic alkalosis
Vomiting will cause which type of acid-base
disturbance?
metabolic acidosis
metabolic
alkalosis
respiratory acidosis
respiratory alkalosis
metabolic alkalosis
Severe anxiety would cause which type of acid-base disturbance? What
would be the compensation?
respiratory alkalosis; kidneys would
excrete HCO3
respiratory alkalosis; kidneys would retain
HCO3
respiratory acidosis; kidneys would excrete
HCO3
metabolic alkalosis; hypoventilation by the lungs
respiratory alkalosis; kidneys would excrete HCO3
This chemical equation shows the reaction of a strong acid and weak base in the bicarbonate buffer system. Provide the products of the following reaction. HCl + NaHCO3 -->
H2CO3 + NaCl
NaHCO3 + H2O
NaH2PO4 + NaCl
NaOH + NaH2PO4
H2CO3 + NaCl
In order to buffer a strong acid into a weak acid, which has a less dramatic effect on pH, what chemical should be used as the buffer?
weak base
weak acid
salt
water
weak base
The most abundant cation in intracellular fluid is potassium.
True
False
True
Which of the following describes the distribution of sodium and
potassium between cells and body fluids?
K+ mainly in the cells,
Na+ in the body fluids
little of either in the cells, but large
amounts of each in the body fluids
Na+ mainly in the cells, K+ in
the body fluids
equal amounts of each ion in the cells and body fluids
K+ mainly in the cells, Na+ in the body fluids
Which of the following statements is true regarding fluid
shifts?
There are always more positive electrolytes than negative
in a solution; it is therefore impossible to follow fluid
shifts.
Nonelectrolytes are the controlling factor in directing
fluid shifts.
Electrolytes are not as important as proteins in
regulating fluid shifts in the body.
Electrolytes have greater
osmotic power than nonelectrolytes and therefore have the greatest
ability to cause fluid shifts.
Electrolytes have greater osmotic power than nonelectrolytes and therefore have the greatest ability to cause fluid shifts.
Adipose tissue is one of the most hydrated of all tissues in the
human body.
True
False
False
Electrolytes determine most of the chemical and physical reactions of
body fluids.
True
False
True
What results from increased levels of aldosterone?
increased Na+ reabsorption
decreased Na+
reabsorption
increased K+ reabsorption
increased Ca2+ reabsorption
increased Na+ reabsorption
Atrial natriuretic peptide is a hormone that is made in the atria of
the heart. The influence of this hormone is to ________.
reduce
blood pressure and blood volume by inhibiting sodium and water
retention
enhance atrial contractions
prevent pH changes
caused by organic acids
activate the renin-angiotensin mechanism
reduce blood pressure and blood volume by inhibiting sodium and water retention
Which of the choices below exerts primary control over sodium levels
in the body?
ADH
water levels
glucocorticoids
aldosterone
aldosterone
Although the sodium content of the body may be altered, its
concentration in the ECF remains relatively stable because of
immediate adjustments in water volume.
True
False
True
Interstitial:
Spaces between cells.
Intracellular:
Fluid compartments located within the cell.
Extracellular:
The fluid compartments outside the cell.
Nonelectrolytes:
Do not dissociate.
Electrolytes:
Dissociate in water.