1. Edouard van Beneden proposed that an egg and a sperm, each
containing half the complement of chromosomes found in somatic cells,
fuse to produce a single cell called a(n) ______.
A.
zygote
B. karyotype
C. embryo
D. oocyte
zygote
2. ______ is a process of nuclear division which reduces the number
of chromosomes per cell from 2 sets to 1 set.
A. Mitosis
B.
Meiosis
C. Binary fission
D. Syngamy
meiosis
3. ______ cells contain one set of chromosomes.
A.
Germ-line
B. Somatic
C. Diploid
D. Haploid
D. Haploid
4. In life cycles that alternate between haploid and diploid stages,
fertilization doubles the number of chromosomes per cell while ______
reduces it in half.
A. mitosis
B. meiosis
C. binary
fission
D. syngamy
meiosis
5. Homologous chromosomes pair along their length during prophase I
of meiosis. While two homologues are paired, genetic exchange may
occur between them in a process called ________.
A.
syngamy
B. synapsis
C. independent assortment
D.
crossing over
crossing over
6. Compared to asexual reproduction, the main advantage of sexual
reproduction is that it
A. requires less energy
B.
increases the genetic diversity of the offspring
C. can produce
more complex offspring
D. can produce a greater number of offspring
B. increases the genetic diversity of the offspring
7. If there were no suppression of DNA replication between meiotic
divisions but cytokinesis proceeded normally, what is the most likely
outcome of meiosis?
A. 4 diploid cells
B. 2 diploid
cells
C. 4 haploid cells
D. 2 haploid cells
E. 2
diploid cells and 2 haploid cells
4 diploid cells
8. Evidence of crossing over can often be seen under the light
microscope as a structure called a _______.
A.
kinetochore
B. centromere
C. chiasma
D. centriole
chiasma
9. The fusion of a male gamete with a female gamete is called
A. syngamy.
B. meiosis.
C. mitosis.
D.
recombination.
E. synapsis.
syngamy
10. Diploid organisms use meiosis to produce haploid cells. Meiosis
consists of how many rounds of nuclear division?
A. one
B.
two
C. three
D. four
E. none of these
two
11. The pairing of chromosomes along their lengths, which is
essential for crossing over, is referred to as
A.
syngamy.
B. synapsis.
C. prophase.
D.
recombination.
E. centromere.
synapsis
12. The cell produced by the fusion of an egg and a sperm is the
A. gamete.
B. oocyte.
C. zygote.
D. germ line
cell.
E. somatic cell.
zygote
13. The zygote has
A. one copy of each chromosome.
B. one
full haploid complement of chromosomes.
C. chromosomes identical
to those of a sperm cell.
D. chromosomes identical to those of an
egg cell.
E. two copies of each chromosome.
E. two copies of each chromosome.
14. All animal cells are diploid except
A. gametes.
B.
muscle cells.
C. nerve cells.
D. germ-line cells.
E.
somatic cells.
gametes
16. Which of the following produces new cells that are genetically
identical to the original cell?
A. meiosis
B.
mitosis
C. crossing over
D. independent assortment
E. fertilization
mitosis
17. In animals, the cells that will eventually undergo meiosis to
produce gametes are set aside early in development. These are called
A. somatic cells.
B. germ-line cells.
C. sex
cells.
D. gametophytes.
E. reproductive cells.
germ-line cells
18. Which of the following events occurs first during meiosis?
A. homologous chromosomes separate and are pulled to opposite
poles of the cell
B. sister chromatids separate and are pulled to
opposite poles of the cell
C. chromosomes decondense
D.
synapsis of homologous chromosomes
E. pairs of homologous
chromosomes align along the equatorial plate
D. synapsis of homologous chromosomes
19. Chromosomes exchange genetic information by
A.
fertilization.
B. mitosis.
C. syngamy.
D. DNA
replication.
E. crossing over.
crossing over
20. Crossing over between homologous chromosomes takes place during
A. prophase II.
B. prophase I.
C. interphase
II.
D. interphase I.
E. metaphase II.
B. prophase I.
21. The synaptonemal complex is
A. a cluster of microtubules at
each pole of the cell.
B. a network of microtubules that forms
the spindle apparatus.
C. a network of proteins that holds
homologues together.
D. the area where microtubules attach to the
centromere of each chromosome.
E. a region of highly coiled DNA.
C. a network of proteins that holds homologues together.
23. Which best describes the process of independent assortment?
A. The way one pair of homologues lines up along the metaphase
plate does not affect how any other pair lines up.
B. Segregation
of chromosomes during meiosis I is independent of their segregation
during meiosis II.
C. During synapsis, chromosomes pair up at
random.
D. Crossing over along one pair of chromosomes is
independent of crossing over along the other pairs.
E. During
synapsis, homologues pair independently of each other.
A. The way one pair of homologues lines up along the metaphase plate does not affect how any other pair lines up.
22. At the end of meiosis II, each of the four resulting cells
contains
A. one full set of chromosomes, each with 2 molecules
of DNA.
B. two full sets of chromosomes, each with 2 molecules of
DNA.
C. one full set of chromosomes, each with 1 molecule of
DNA.
D. two full sets of chromosomes, each with 1 molecule of DNA.
C. one full set of chromosomes, each with 1 molecule of DNA.
24. In plants and animals, the zygote develops by which of the
following processes?
A. mitosis
B. meiosis
C.
syngamy
D. synapsis
E. reduction division
mitosis
25. The pairing of homologous chromosomes is called
A.
syngamy.
B. synapsis.
C. alignment.
D. independent
assortment.
E. crossing over.
synapsis
26. Which best explains the process of meiosis?
A. The cells
that result from meiosis I are haploid, and each chromosome consists
of 1 chromatid.
B. The cells that result from meiosis I are
haploid, and each chromosome consists of 2 chromatids.
C. The
cells that result from meiosis II are haploid, and each chromosome
consists of 2 chromatids.
D. The cells that result from meiosis I
are diploid, and each chromosome consists of 2 chromatids.
E. The
cells that result from meiosis I are diploid, and each chromosome
consists of 1 chromatid.
B. The cells that result from meiosis I are haploid, and each chromosome consists of 2 chromatids.
27. During meiosis, sister chromatids are held together by
A. a
common centromere and kinetochore microtubules.
B. a common
centromere and chiasmata.
C. a common centromere and polar
microtubules.
D. a common centromere and a protein called
cohesion.
E. the kinetochores and a protein called cohesion.
D. a common centromere and a protein called cohesion.
28. What immediately follows meiosis I?
A. DNA
replication
B. prophase II
C. metaphase II
D. synapsis
of homologues
E. crossing over of homologues
B. prophase II
29. All of the following increase genetic variation EXCEPT
A.
crossing over.
B. random fertilization.
C. independent
assortment.
D. mitosis.
E. mutation.
mitosis
30. One of a pair of chromosomes with similar genetic information and
from different sources like the sperm and egg.
A.
chiasma
B. homologue
C. kinetochore
D. synapsis
E. synaptonemal
homologue
31. Which structures indicate where crossing over has occurred.
A. chiasmata
B. centromeres
C. kinetochores
D.
centrioles
E. spindle fibers
chiasmata
32. Which structure holds two homologous chromosomes together?
A. centromere
B. kinetochore
C. polar
microtubules
D. spindle apparatus
E. synaptonemal complex
E. synaptonemal complex
33. During anaphase I, which best represents segregation of the
chromatids that make up one pair of homologues? (M represents a
maternal chromatid and P represents a paternal chromatid. Assume no
crossing over occurs.)
A. M and M to one pole; P and P to the
other pole.
B. M and P to one pole; M and P to the other
pole.
C. M to one pole; P to the other pole.
D. half of M
and half of P to each pole.
E. the segregation of these
chromatids is completely random.
A. M and M to one pole; P and P to the other pole.
34. You are studying meiosis in an organism where 2n= 28. How many
chromosomes will be present in each cell after meiosis I is complete
but before meiosis II begins?
A. 7
B. 14
C. 28
D. 56
B. 14
35. You are studying meiosis in an organism where 2n=24. How many
chromosomes will each nucleus have after meiosis II is
complete?
A. 24
B. 12
C. 6
D. 48
B. 12
36. You are comparing the events of meiosis I in cells from several
different organisms. You come across one species in which you do not
observe any chiasmata. The best conclusion to make is
A. there is
no crossing over between non-sister chromatids
B. kinetochores of
sister chromatids do not fuse
C. the chromosome pairs will not
assort independently
D. chiasmata will form during meiosis II
A. there is no crossing over between non-sister chromatids
22. At the end of meiosis II, each of the four resulting cells
contains
A. one full set of chromosomes, each with 2 molecules
of DNA.
B. two full sets of chromosomes, each with 2 molecules of
DNA.
C. one full set of chromosomes, each with 1 molecule of
DNA.
D. two full sets of chromosomes, each with 1 molecule of DNA.
C. one full set of chromosomes, each with 1 molecule of DNA.
37. Which statement about the reductive division of meiosis is
false?
A. During the reductive division, homologues migrate to
opposite poles of the cell.
B. During the reductive division,
sister chromatids migrate to opposite poles of the cell.
C.
During the reductive division, centromeres do not divide.
D. At
the end of the reductive division, each daughter nucleus has one-half
as many centromeres as the parental nucleus.
B. During the reductive division, sister chromatids migrate to opposite poles of the cell.
38. The Rec8 protein holds sister chromatids together during meiosis.
If an individual has a mutation that prevents degradation of Rec8,
this would most likely prevent
A. normal segregation during
meiosis I
B. normal segregation during meiosis II
C.
synapsis of homologous chromosomes
D. crossing over during
prophase I
B. normal segregation during meiosis II
39. Which of the following is likely to occur if you were to prevent
cyclin B from associating with its cyclin-dependent kinase near the
end of meiosis I?
A. failure to maintain sister chromatid
cohesion at the centromere
B. failure to form initiation
complexes necessary for DNA replication to proceed
C. suppression
of DNA replication
D. activation of DNA replication
D. activation of DNA replication
40. Which of the following statements about crossing over is
false?
A. Crossing over takes place between non-sister
chromatids.
B. Crossing over takes place between sister
chromatids.
C. Crossing over occurs during prophase I.
D.
Sites of crossing over are called chiasmata.
E. Crossing over is
also called genetic recombination.
B. Crossing over takes place between sister chromatids.
41. A life cycle that regularly alternates between haploid and
diploid stages is found in all of the following EXCEPT
A.
dogs
B. the bacterium E. coli
C. alfalfa plants
D. the
mold N. crassa
B. the bacterium E. coli
42. In 95% of cases of Down's syndrome, there is one extra chromosome
(number 21) in every cell. This aneuploid condition is most likely the
result of
A. failure to suppress DNA replication between meiosis
I and meiosis II
B. failure of the chromosomes to assort
independently during meiosis
C. failure of 1 homologous pair to
segregate during meiosis.
D. failure of 2 homologous pairs to
segregate during meiosis
E. failure of the cytoplasm to divide at
the end of meiosis II
C. failure of 1 homologous pair to segregate during meiosis.
43. Why does sexual reproduction require both meiosis and
syngamy?
A. The process of meiosis results in the production of
gametes in which the number of chromosomes remains the same. During
syngamy, two gametes fuse to form a new cell, and the number of
chromosomes is restored to the full amount. Therefore, by coupling
meiosis and syngamy, the organism ensures that the proper number of
chromosomes will be maintained.
B. The process of meiosis results
in the production of gametes in which the number of chromosomes is
reduced by half. During syngamy, two gametes fuse to form a new cell,
and the number of chromosomes is restored to the full amount.
Therefore, by coupling meiosis and syngamy, the organism ensures that
the proper number of chromosomes will be maintained.
C. The
process of meiosis results in the production of gametes in which the
number of chromosomes is doubled. During syngamy, gametes are reduced
by half, and the number of chromosomes is restored to the full amount.
Therefore, by coupling meiosis and syngamy, the organism ensures that
the proper number of chromosomes will be maintained.
B. The process of meiosis results in the production of gametes in which the number of chromosomes is reduced by half. During syngamy, two gametes fuse to form a new cell, and the number of chromosomes is restored to the full amount. Therefore, by coupling meiosis and syngamy, the organism ensures that the proper number of chromosomes will be maintained.
44. Which cells never divide by meiosis? (Check all that
apply.)
__X__ haploid cells
_____ diploid cells
__X__
somatic cells
_____ germ-line cells
__X__ zygotes
__X__ haploid cells
__X__ somatic cells
__X__ zygotes
45. A cell biologist examines a skin cell from a lizard during
metaphase of mitosis and determines that 20 chromatids are present.
The role of meiosis in this species is to (Check all that
apply)
__X__ Produce 4 daughter cells that are genetically
different from each other
__X__ Produce 4 daughter cells that are
genetically different from the original parental cell
__X__
Reduce the number of chromosomes per cell from 10 to 5
_____
Reduce the number of chromosomes per cell from 20 to 10
_X__ Produce 4 daughter cells that are genetically different from
each other
__X__ Produce 4 daughter cells that are genetically
different from the original parental cell
__X__ Reduce the number
of chromosomes per cell from 10 to 5
46. A cell biologist examines a leaf cell from an alfalfa plant
during metaphase of mitosis and determines that 32 chromatids are
present. The role of fertilization in this species is to (Check all
that apply)
__X__ Produce a new cell that has a combination of
chromosomes from 2 different parents
_____ Increase the number of
chromosomes per cell from 16 to 32
__X__ Increase the number of
chromosomes per cell from 8 to 16
__X__ Combine the chromosomes
from 2 haploid cells into a single diploid cell
__X__ Produce a new cell that has a combination of chromosomes from 2
different parents
__X__ Increase the number of chromosomes per
cell from 8 to 16
__X__ Combine the chromosomes from 2 haploid
cells into a single diploid cell
47. The most common form of gene therapy involves inserting a normal
gene into cells that contain a defective version of the gene. In order
to use gene therapy to prevent a man from passing a defective gene on
to future generations, you should try to insert normal copies of the
gene into
A. blood cells
B. germ-line cells
C. somatic
cells in the testes
D. bone marrow cells
B. germ-line cells
48. If a germ-line cell from an owl contains 8 picograms of DNA during G1 of interphase, how many picograms of DNA would be present in each cell during prophase I of meiosis? (Enter the number only, not the units.)
16
49. If a somatic cell from a cat contains 40 picograms of DNA during G2 of interphase, how many picograms of DNA would be present in each cell during metaphase II of meiosis? (Enter the number only, not the units.)
20
50. If a germ-line cell from a salamander contains 10 picograms of DNA during G1 of interphase, how many picograms of DNA would be present in each gamete produced by this species? (Enter the number only, not the units.)
5
51. How many tetrads are present in a single elephant cell (2n=56) during metaphase I of meiosis?
28
52. A geneticist examines a somatic cell from a fly during metaphase
of mitosis and determines that 16 chromatids are present. If a
germ-line cell from this species divides by meiosis, then at the end
of meiosis I (including the first cytokinesis) each cell will
contain
A. 8 chromosomes with 8 DNA molecules
B. 8
chromosomes with 16 DNA molecules
C. 4 chromosomes with 4 DNA
molecules
D. 4 chromosomes with 8 DNA molecules
D. 4 chromosomes with 8 DNA molecules
53. Nondisjunction is the failure of homologous chromosomes to
separate during meiosis I, or the failure of sister chromatids to
separate during meiosis II or mitosis. As a result, both homologous
chromosomes or both sister chromatids migrate to the same pole of the
cell. This produces daughter cells with an imbalance of chromosomes. A
cell biologist examines the final products of meiosis in an earthworm
(2n=36) and finds 2 cells with 20 chromosomes, and 2 cells with 16
chromosomes. Most likely this was because
A. 2 pairs of sister
chromatids failed to separate during meiosis II
B. 1 pair of
sister chromatids failed to separate during meiosis II
C. 2 pairs
of homologous chromosomes failed to separate during meiosis I
D.
1 pair of homologous chromosomes failed to separate during meiosis I
C. 2 pairs of homologous chromosomes failed to separate during meiosis I
54. Nondisjunction is the failure of homologous chromosomes to
separate during meiosis I, or the failure of sister chromatids to
separate during meiosis II or mitosis. As a result, both homologous
chromosomes or both sister chromatids migrate to the same pole of the
cell. This produces daughter cells with an imbalance of chromosomes.
If 18 pairs of sister chromatids segregate normally during meiosis II
in cats (n=19) but we have nondisjunction of 1 pair, then at the end
of meiosis II we will have
A. 3 cells with 20 chromosomes and 1
cell with 18
B. 2 cells with 20 chromosomes and 2 cells with
18
C. 2 cells with 19 chromosomes, 1 with 20, and 1 with
18
D. 3 cells with 18 chromosomes and 1 cell with 20
C. 2 cells with 19 chromosomes, 1 with 20, and 1 with 18
55. A cell biologist examines a diploid cell from a particular species of during metaphase of mitosis and determines that 8 centromeres are present. Based on this finding, how many centromeres should be present in a single cell from this species during anaphase II of meiosis?
8
56. A cell biologist examines a diploid cell from a particular species of butterfly during prometaphase of mitosis and determines that 10 centromeres are present. Based on this finding, how many chromatids should be present in a single cell from this species in metaphase I of meiosis?
20
57. Meiosis results in a reassortment of maternal chromosomes
(inherited from the mother) and paternal chromosomes (inherited from
the father.) If n=4 for a given species, and ignoring the effects of
crossing over, what is the probability that a gamete will receive only
paternal chromosomes?
A. 1/2
B. 1/4
C. 1/8
D. 1/16
1/16
58. A cell in G2 before meiosis begins, compared with one of the four
cells produced at the end of meiosis II, has
A. twice as much DNA
and twice as many chromosomes
B. four times as much DNA and twice
as many chromosomes
C. twice as much DNA but the same number of
chromosomes
D. four times as much DNA and four times as many
chromosomes
E. twice as much DNA and half as many chromosomes
B. four times as much DNA and twice as many chromosomes
59. In meiosis, sister kinetochores are attached to the same pole of
the cell during meiosis I, and sister chromatid cohesion is released
during anaphase II. What would be the likely result if sister
kinetochores were attached to different poles of the cell during
meiosis I and sister chromatid cohesion was released during anaphase
I?
A. sister chromatids would migrate to opposite poles during
anaphase I
B. sister chromatids would migrate to opposite poles
during anaphase II
C. sister chromatids would migrate to the same
pole during anaphase I
D. sister chromatids would migrate to the
same pole during anaphase II
A. sister chromatids would migrate to opposite poles during anaphase I
60. Sister chromatids move to opposite poles of the cell during
(Check all that apply.)
_____ anaphase I of meiosis
_____
metaphase I of meiosis
__X__ anaphase II of meiosis
__X__
anaphase of mitosis
__X__ anaphase II of meiosis
__X__ anaphase of mitosis
15. The point of connection between two sister chromatids, before
anaphase II of meiosis separates them, is called the
A.
centriole
B. kinetochore.
C. centromere.
D. spindle
apparatus.
E. centrosome.
C. centromere.