What is unique about the Hepadnaviridae family of viruses?
They contain both single-stranded DNA and double stranded DNA
Which of the following characteristics are common to Poxviridae, Herpesviridae, and Hepadnaviridae?
double-stranded DNA in the virion and the presence of an envelope
Which among the following are the largest DNA viruses that infect humans?
Poxviridae
Which of the following lesions is a hard, raised sore?
papule
High fever, headache, extreme fatigue, and a rash on the face that progresses to fluid and pus filled sores before crusting over and healing are signs and symptoms consistent with infection with
poxvirus
Which of the following statements is true of both molluscum contagiosum and smallpox?
the causative agent is a large dsDNA virus with a complex capsid
Which of the following poxviruses are zoonoses?
both cowpox and monkeypox
A teenager shows up at a clinic with lesions on his face. The sores are raised light colored bumps with a waxy texture. A few similar lesions are present on the torso as well. With which of the following viruses might he be infected?
molluscum contagiosum
Which of the following families of DNA viruses is the most prevalent in humans?
herpesviridae
What cell type can the Simplexviruses infect latently?
epithelial cells
An older adult is complaining of an intensely painful rash that has appeared as a patch on one side of his chest. This description is consistent with
shingles
Which of the following human herpesvirus infections is associated with a 30-80% fatality rate?
neonatal herpes
Characteristic features of the herpesvirus used for diagnosis include the
presence of recurring lesions in the lip or genital regions and syncytia in infected tissue
Shingles or herpes zoster, is caused by the virus that also causes
chickenpox
Human herpesvirus 4 (EBV) is implicated in which of the following diseases?
Burkitt's lymphoma, chronic fatigue syndrome and oral hairy leukoplakia
What is the most prevalent viral infection seen in neonates?
cytomegalovirus
Where does human herpesvirus 4 (EBV) become latent?
in B lymphocytes
Which of the following statements concerning genital warts is FALSE?
the incidence is relatively low because treatment is available
Pinkeye is caused by
an adenovirus
Which of the following statements about the polyoma BK virus is TRUE?
it can reactivate and cause severe urinary tract disease
Which of the following viruses is a DNA virus that infects liver cells?
hepadnaviruses
Adenoviruses infect
both the digestive tract and the respiratory tract
A young man goes to a clinic complaining of discomfort in his foot especially when standing. Upon examination, the clinician observes raised bumps with rough surfaces on the sole of his foot. These lesions are consistent with
warts
Which of the following is the only DNA virus that that can cause viral hepatitis?
hepatitis B virus
Gamma interferon is sometimes used to treat infections with
adenoviruses
Which of the following increases the risk of permanent liver damage with hepatitis B infection?
coinfection with hepatitis D virus
Hepatitis B virus releases a large amount of viral antigen, which benefits the patient by
ensuring plentiful substrate for binding with labeled antibodies in diagnostic tests.
Which of the following statements concerning the hepatitis B vaccine is FALSE?
it must be repeated every five years
Which of the following statements regarding the association of hepatitis B with live cancer is FALSE?
vaccination does not provide protection against the development of hepatic cancer.
Which of the following viruses are the only ssDNA viruses that cause disease in humans?
Parvoviridae
Which of the following viruses is responsible for erythema infectiosum?
B19 virus
A scientist discovers a new virus that causes mild respiratory disease in humans. He is able to isolate, purify, and characterize the virus. the virus preparation contains double stranded DNA and no lipid. to which of the following virus families does this new virus likely belong?
Adenoviridae
The large size of poxviruses allows them to
be potential vectors for introduction of genetic material in vaccinations for gene therapy
Which of the following viruses exist only in laboratory stocks?
smallpox
Which of the following viruses are oncogenic?
both human herpesvirus 4 and papillomavirus
The common name for the disease caused by human parvovirus B19 is
fifth disease
A blood sample showing neutropenia and large B lymphocytes with atypical nuclei is characteristic of infection with
Epstein-Barr virus (EBV)
What conditions may trigger reactivation of latent herpesvirus infections?
Fever, stress, immune suppression, or hormonal changes can all trigger reactivation
Vaccinia, or cowpox, was used to eradicate the related small pox virus. this would make it an
attenuated vaccine
A homeschooled child recently visited an ailing great-grandparent who was complaining of a painful rash. Even though the child had had no contact with children suffering from chickenpox, the child developed chickenpox. how id the child contract the infection?
the adult had shingles and the child was exposed to virus particles
Reactivation of latent _______ in immunosuppressed individuals may result in disease of the brain known as progressive multifocal leukoencephalopathy (PLM).
JC virus
Reactivation of _______ in immunosuppressed persons may produce Kaposi's sarcoma, a cancer of the blood vessels.
HHV-8
Virions known as Dane particles are the infectious form of
hepatitis B
A childhood illness caused by a herpesvirus and characterized by a "rosy" rash all over the body is known as
roseola
Infection of the respiratory system by _____ may develop into symptoms of a common cold
adenoviruses
Immunization with (chickenpox/ cowpox/ monkeypox) will provide protection against smallpox.
cowpox
Painful, blister-like lesions that progressively become filled with pus suggest infection with a (herpesvirus/ poxvirus).
poxvirus
Human herpesvirus (1/ 2/ 3/ 4) is usually associated with lesions on the genitalia.
2
An inflamed blister on the finger caused by either HHV-1 or HHV-2 is known as a (blister/ wart/ whitlow).
whitlow
The condition in which athletes develop herpes lesions on their skin as a result of coming in contact with herpes lesions during wrestling is known as herpes (gladiatorum/ whitlow/ zoster).
gladiatorum
Skin lesions described as "dewdrops on rose petals" are characteristic of (chickenpox/ shingles).
chickenpox
Individuals who have had chickenpox may develop (cancer/ shingles/ whitlow) later in life if they experience severe stress or immune suppression.
shingles
Papillomaviruses are transmitted by (aerosols/ direct contact/ secretions).
direct contact
In infections with human herpesvirus (1/ 2/3 / 4) the virus becomes latent in B lymphocytes and suppresses apoptosis, thus providing one source of lymphomas associated with this virus.
4
The autoimmune disease multiple sclerosis may result from infection with human herpesvirus (3/ 4/ 6/ 8).
6
Cytomegalovirus can be (chronic/ oncogenic/ teratogenic) if it infects fetal stem cells.
teratogenic
The cauliflower-like growths on the genitalia called condylomata acuminate are caused by (herpesviruses/ papillomaviruses/ parvoviruses)
papillomaviruses
The search for cancer-causing viruses led scientists to discover a group of viruses called (papillomaviruses/ parvoviruses/ polyomaviruses) that are capable of causing several different types of tumors in humans.
polyomaviruses
Hepatitis B virus replicates in the liver cells and is released by (exocytosis/ lysis), which contributes to the infection becoming chronic.
exocytosis
The disease caused by B19 virus, a (papilomavirus/ parvovirus/ polyomavirus), is known as erythema infectiosum and produces a distinctive rash.
parvovirus