____________ are the most common type of infection
Infections of the upper respiratory system
True or False
Pathogens that enter the respiratory system can infect other parts of the body.
True
The upper respiratory system consists of ______________
the nose, pharynx, and associated structures, such as the
middle ear and auditory tubes.
True or False
Coarse hairs in the nose filter large particles from air entering the respiratory tract
True
___________ of the nose and throat trap airborne particles and remove them from
the body.
The ciliated mucous membranes
____________ provide immunity to certain infections
. Lymphoid tissue, tonsils, and adenoids
The lower respiratory system consists of the ___________________
larynx, trachea, bronchial tubes, and alveoli.
Microbes in the lungs can be phagocytized by
alveolar macrophages
Respiratory mucus contains _____ antibodies
IgA
The lower respiratory system is usually sterile because of the action of the ___________
ciliary escalator
Specific areas of the upper respiratory system can become infected to produce
pharyngitis, laryngitis,
tonsillitis, sinusitis, and epiglottitis.
True or False
Most respiratory tract infections are self-limiting
True
__________________________ can cause epiglottitis
H. influenza type b
Streptococcal Pharyngitis is caused by
group A beta-hemolytic streptococci
group A beta-hemolytic streptococci consists of
Streptococcus
pyogenes.
Symptoms of Streptococcal Pharyngitis (Strep Throat) are:
inflammation of the mucous membrane
fever
tonsillitis
otitis media
Rapid diagnosis of Strept Throat is made by _______________
enzyme immunoassays
True or False
Rapid Strept Tests are sensitive and specific
False
They are not very sensitive or specific
True or False
Negative tests must be confirmed by culture or another type of test.
True
True or False.
Immunity to streptococcal infections is type-specific
True
Strep throat, if left untreated results in ___________
Scarlet Fever
___________ produces erythrogenic toxin when lysogenized by a phage
S. pyogenes
Symptoms of Scarlet Fever include:
red rash
high fever
red, enlarged tongue
Diphtheria is caused by exotoxin-producing _________
Corynebacterium diphtheriae
Diptheria exotoxin is produced when the bacteria are _______________
lysogenized by a phage
True or False
With Diptheria A membrane, containing fibrin and dead human and bacterial cells, forms in the throat and can block the passage of air.
True
The diptheria exotoxin inhibits ____________, and heart, kidney, or nerve damage may result
protein synthesis
Routine immunization in the United States includes diphtheria toxoid in the ___________
DTaP vaccine
Slow-healing skin ulcerations are characteristic of _________________
cutaneous diphtheria
Bacterial causes of Otitis Media include
Streptococcus pneumoniae, nonencapsulated Haemophilus influenzae, Moraxella
catarrhalis, Streptococcus pyogenes, and Staphylococcus aureus.
Any one of approximately 200 different viruses can cause the common cold
rhinoviruses cause about
50% of all colds.
Symptoms of the Common Cold include
sneezing, nasal secretions, and congestion
Rhinoviruses grow best
slightly below body temperature
True or False
Antibodies are produced against the specific viruses.
True
True or False
Many of the same microorganisms that infect the upper respiratory system also infect the lower respiratory
system
True
Diseases of the lower respiratory system include
bronchitis and pneumonia.
Pertussis is caused by
Bordetella pertussis
The initial stage of pertussis resembles a cold and is called the _____________
catarrhal stage
During Pertussis (Whooping Cough) The accumulation of mucus in the trachea and bronchi causes deep coughs characteristic of the ___________
paroxysmal
(second) stage
The third stage of pertussis is the ________ stage and can last for months
convalescence
True or false
Regular immunization for children has decreased the incidence of pertussis
True
Tuberculosis is caused by ________________
Mycobacterium tuberculosis
In Tuberculosis what accounts for the bacterium’s acid-fast characteristic as well as its resistance to drying and disinfectants?
Large amounts of lipids in the cell wall
M. tuberculosis may be ingested by _________________
alveolar macrophages
True or False
if M. tuberculosis is not killed, the bacteria reproduce in the macrophages.
True
Lesions formed by M. tuberculosis are called ________
tubercles
During Tuberculosis, dead macrophages and bacteria form the caseous lesion that might calcify and appear in an X-ray image as a ___________
Ghon’s complex
____________________ results in a tuberculous cavity in which M. tuberculosis can grow.
Liquefaction of the caseous lesion
New foci of infection can develop when a caseous lesion ruptures and releases bacteria into blood
or lymph vessels; this is called ____________.
miliary tuberculosis.
Miliary tuberculosis is characterized by _______________________________
weight loss, coughing, and loss of vigor
True or False
A positive tuberculin skin test can indicate either an active case of TB, prior infection, or vaccination
and immunity to the disease
True
_____________ causes bovine tuberculosis and can be transmitted to humans by unpasteurized
milk.
Mycobacterium bovis
M. bovis infections usually affect the __________________________________
bones or lymphatic system
True or False
Mycobacterium bovis causes bovine tuberculosis and can be transmitted to humans by unpasteurized
milk.
True
Typical community-acquired pneumonia is caused by
S. pneumoniae
Atypical pneumonias are caused by other microorganisms. Nosocomial pneumonia’s often caused by
gram negative rods.
Pneumococcal pneumonia is caused by __________________
encapsulated Streptococcus pneumoniae.
Syptoms are Pneumococcal Pneumonia are
fever, breathing difficulty, chest pain, and rust-colored sputum.
A vaccine of pneumococcal pneumonia consists of purified capsular material from ___________________________
23 serotypes of S. pneumoniae
Alcoholism, poor nutrition, cancer, and diabetes are predisposing factors for _______________________.
H. influenzae pneumonia
H. influenzae is a gram ______ _________
gram-negative coccobacillus
____________ causes mycoplasmal pneumonia
Mycoplasma pneumoniae
Mycoplasmal Pneumonia is an ____________ disease
endemic
Mycoplasmal Pneumonia Often occurs in adolescents and young adults; may be referred to as __________________.
Walking pneumonia
Legionellosis is caused by ____________________
Legionella pneumophila
Legionellosis is an aerobic gram _______
negative
Legionaries disease can grow in
water, such as air-conditioning cooling towers, and then be disseminated in the air.
Legionella pneumonia :
A) does not appear to be transmitted from person to person
B) does appear to be transmitted from person to person
A) does not appear to be transmitted from person to person
Commercial bird handlers are most susceptible to this disease.
Psittacosis (Ornithosis)
Psittacosis is caused by
Chlamydophila psittaci
Chlamydophila psittaci is transmitted by
contact with contaminated droppings and exudates of fowl.
How does Chlamydophila psittaci {Psittacosis (ornithosis)} bacteria survive outside a host
Elementary bodies
Chlamydophila pneumoniae causes pneumonia
pneumonia
True or False
Chlamydophila pneumoniae is transmitted from person to person.
True
________ causes Q fever
Coxiella burnetii
Q Fever is usually transmitted to humans through
unpasteurized milk or inhalation of aerosols
in dairy barns
_____ is the most common cause of pneumonia in infants
RSV (Respiratory Syncytial Virus)
Influenza is caused by ________ and is characterized by chills, fever, headache, and general muscular
aches.
Influenza virus
_________ and __________ spikes project from the outer lipid bilayer of the virus.
Hemagglutinin (HA) and neuraminidase (NA) spikes
Viral strains are identified by ___________
antigenic differences in the HA and NA spikes
Viral strains are divided by antigenic differences in their __________
protein coats (A, B, and C).
Viral isolates are identified by hemagglutination-inhibition tests and immunofluorescence testing
with _________________
monoclonal antibodies
________________ alter the antigenic nature of the HA and NA spikes
Antigenic shifts
Minor antigenic changes are caused by ________________.
antigenic drift
Deaths during an influenza epidemic are usually from
secondary bacterial infections
________________ are available for older adults and other high-risk groups
Multivalent vaccines
____________ and _____________ are effective prophylactic and curative drugs against influenza A virus
Amantadine and rimantadine
True or False
Fungal spores are easily inhaled; they may germinate in the lower respiratory tract.
True
True or False
The incidence of fungal diseases has been decreasing in recent years
False. It has been increasing
______________ causes Histoplasmosis
Histoplasma capsulatum
what is histoplasmosis
causes a subclinical respiratory infection that only occasionally progresses to a severe, generalized disease.
how do you diagnoses Histoplasmosis
Isolating or identifying the fungus in tissue
___________________________________ can result in coccidioidomycosis
Inhaling the airborne arthroconidia of Coccidioides immitis
If you have coccidioidomycosis when there are predisposing factors such as fatigue and poor nutrition, a progressive disease resembling ___________ can result.
tuberculosis
During Pneumocystis Pneumonia, _______________is found in healthy human lungs
Pneumocystis jirovecii
True or False
P. jirovecii causes disease in immunosuppressed patients.
True
_____________ is the causative agent of blastomycosis
Blastomyces dermatitidis
Blastomycosis infection begins in the _______ and can spread to cause extensive abscesses
lungs
Histoplasmis, Coccidioidomycosis, Pneumocystis Pneumonia, Blastomycosis can be treated with ___________
amphotericin B