BYS 219F24 Exam II_key Flashcards


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1

haplotype

group of genes that are inherited together on the same chromosome

2

fragile sites

areas of chromosome that appears to be susceptible to chromosome breakage

3

inversion

chromosomal aberration

4

gene duplication

groups of contiguous genes whose products perform the same

5

NOR

rDNA genes are all found in a single area of the chromosome

6

duplication

a single locus or a large piece of chromosome

7

translocation

Rearrangement of genetic material in which a chromosome segment is exchanged with a segment of a nonhomologous chromosome

8

diploids, tetraploids

Triploids can be produced under experimental conditions by crossing ___ with ___

9

n, 2n

diploid organisms produce gametes with ____chromosomes, while tetraploids produce _

10

allotetraploid

an organism that is a tetraploid resulting from hybridizing two closely related species

11

Who won the Nobel Prize for deciphering the molecular structure of DNA and suggesting a
mechanism for copying genetic material?

Francis Crick, James Watson and Maurice Wilkins

12

fragile x syndrome

high numbers of
trinucleotide repeats

13

cri du chat syndrome

deletion of a small terminal
portion of chromosome 5

14

Considering the structure of double-stranded DNA, which kind(s) of bonds hold one complementary strand to the other?

hydrogen

15

Which is NOT a major feature of the Watson and Crick DNA model?

a complete turn is 20 angstroms

16

Regarding the structure of DNA, the covalently arranged combination of a deoxyribose and a
nitrogenous base would be called a(n) _______

nucleoside

17

In the classic experiment conducted by Hershey and Chase, why was the pellet radioactive in the centrifuge tube that contained bacteria with viruses?

The bacteria were in the pellet, many of which contained the radioactive viral DNA

18

In 1927 Frederick Griffith combined an extract from heat-killed smooth bacterial cells with live rough cells and injected them into mice. The findings and conclusions of the experiment
were ________.

mice died as a result of a transforming agent picked up by the rough cells from the smooth cell
extract

19

A generalized transduction experiment is set up so that a phage is carrying a donor strain with the
genotype met+ bio+ thr+ . This donor strain is used to transduce a recipient E. coli strain with the genotype
met− bio− thr− . After transduction, the recipient population is plated on a minimal medium containing only
organic salts and a simple carbon source supplemented with methionine and biotin. A large number of
colonies are obtained. Out of the following choices, select the possible genotype of the colonies that grew
on this medium

met− bio− thr+

20

From one F+ strain the following three Hfr strains were derived, each shown with the first three markers transferred in an Hfr X F- cross.
Hfr1...DAG->
Hfr2...GBE->
Hfr3...ECD->
The order of genes on the bacterial chromosome circle must be ________. (A is shown at both
ends to represent circularity)

ADCEBGA

21

An Hfr strain (met+ ,his + , arg + , str S) is mated with an F strain (met - , his - , arg - , str R),grown in
complete media, then plated on minimal media supplemented with streptomycin, histidine, and
arginine. The few colonies that grow on the plate indicate that ________

the wild-type methionine gene has been transferred from Hfr to F

22

Which of the following is a true statement?

a bacterial colony found on minimal media consists of cells derived from a single prototroph
cell.

23

In Drosophila, the X chromosome may become attached to one another (XX) such that they always segregate together. Some flies thus contain a set of attached X chromosomes plus a Y
chromosome. What sex would such a fly be

female

24

Which of the following may be involve with sex determination in mammals, vertebrate or invertebrates?

temperature and ratio of X chromosomes to sets of autosomes

25

The sexual phenotypes in Caenorhabditis elegans include

males and hermaphrodites

26

Which of the following are heterogametic?

none of the above

27

A fruit fly with a chromosome formulation of 2X:3A would be which of the following?

intersex

28

Which of the following has one Barr body?

klinefelter's and normal female

29

For an individual with the XXY chromosomal composition, the expected number of Barr bodies in interphase cells is ________

one

30

The sex of birds, some insects, and other organisms is determined by a ZW chromosomal arrangement in which the males have like sex chromosomes (ZZ) and females are ZW (similar to XY in humans). Assume that a recessive lethal allele on the Z chromosome causes death of an embryo in birds. What sex ratio would result in the offspring if a cross were made between a male heterozygous for the lethal allele and a normal female

2:1 male to female

31

Klinefelter syndrome in humans, which leads to underdeveloped testes and sterility, is caused by which chromosomal condition?

47, XXY

32

Autotriploids can arise by

two of the above

33

A small part of the human Y chromosome contains the gene that is responsible for determining maleness. What is the name of this gene?

sex determining region Y

34

How many chromosomes do Humans have in a somatic cell?

46

35

All the genes that serve as the underlying basis of sex determination are located on only
sex chromosomes.

false