T/F Microbiology questions Flashcards


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1

An environment may contain some microbes and still be considered sterile.

True

2

Some viruses are inactivated by the same chemical or physical agents that damage
cytoplasmic membranes.

True

3

UV light has the most effect on protein structure.

False

4

Antimicrobial agents usually work best at high temperatures and pH levels.

False

5

The phenol coefficient is one of the most widely used measurements of an antimicrobial
agent's effectiveness.

False

6

No chemical or antimicrobial agents inactivate prions.

False

7

The decimal reduction time is the time required to kill all the microbes in a given sample.

False

8

Slow freezing is more damaging to microbial cells than quick freezing.

True

9

Hydrogen peroxide is an effective antiseptic.

False

10

By themselves, soaps have only degerming activity, not antimicrobial activity.

True

11

Reactions that are both catabolic and anabolic are
amphibolic

True

12

NAD+ and NADP+ are important examples of both coenzymes and electron carriers

True

13

Environmental changes can result in the inactivation of
enzymes.

True

14

As the concentration of substrate increases, the activity of the enzyme decreases

False

15

Ribozymes are enzymes that cleave the subunits of the
ribosome

False

16

During chemiosmosis, electrons are pumped across a membrane to produce ATP

False

17

Fermentation pathways provide a cell with an alternative way to regenerate NAD+ for glycolysis.

True

18

Glucose is used as an energy source only when proteins and fats are not available.

False

19

Essential amino acids are amino acids that cannot be synthesized by an organism and so must be provided as nutrients.

True

20

The pentose phosphate pathway generates all the necessary precursors for nucleotide biosynthesis.

False

21

Paul Erhlich coined the term antibiotics for the "magic bullet" antimicrobials he pursued

False

22

Antisense nucleic acids are designed to have no side effects against humans

True

23

Beta-lactam drugs act by inhibiting formation of the cytoplasmic membrane

False

24

Because all cells engage in protein synthesis, there are few antimicrobial drugs that selectively inhibit this process.

False

25

Many antimicrobial drugs that affect the cytoplasmic membrane are used only externally because they can be toxic to humans

True

26

Some bacterial cells are resistant to a variety of antimicrobials because they actively pump the
drugs out of the cell

True

27

The outer membrane of Gram-negative bacteria enables many antimicrobial drugs to enter the cell more easily.

False

28

If a subculture of an MIC test grows in an MBC test, the concentration of the drug was
bactericidal

False

29

Brain and spinal cord infections are difficult to treat because most antimicrobial drugs cannot diffuse out of the blood into these organs

True

30

Organs that are commonly affected by drug toxicity include the kidneys and the liver

True