According to Beadle and Tatum's hypothesis, how many genes
are necessary for this
pathway?
A) 0
B) 1
C)
2
D) 3
E) It cannot be determined from the pathway.
2
A mutation results in a defective enzyme A. Which of the following
would be a consequence
of that mutation?
A) an accumulation
of A and no production of B and C
B) an accumulation of A and B
and no production of C
C) an accumulation of B and no production
of A and C
D) an accumulation of B and C and no production of
A
E) an accumulation of C and no production of A and B
an accumulation of A and no production of B and C
If A, B, and C are all required for growth, a strain that is mutant
for the gene-encoding
enzyme A would be able to grow on which of
the following media?
A) minimal medium
B) minimal medium
supplemented with nutrient A only
C) minimal medium supplemented
with nutrient B only
D) minimal medium supplemented with nutrient
C only
E) minimal medium supplemented with nutrients A and C
minimal medium supplemented with nutrient B only
If A, B, and C are all required for growth, a strain mutant for the
gene-encoding enzyme B
would be capable of growing on which of
the following media?
A) minimal medium
B) minimal medium
supplemented with A only
C) minimal medium supplemented with B
only
D) minimal medium supplemented with C only
E) minimal
medium supplemented with nutrients A and B
minimal medium supplemented with C only
A possible sequence of nucleotides in the template strand of DNA that
would code for the
polypeptide sequence phe-leu-ile-val would
be
A) 5' TTG-CTA-CAG-TAG 3'
B) 3' AAC-GAC-GUC-AUA 5'
C)
5' AUG-CTG-CAG-TAT 3'
D) 3' AAA-AAT-ATA-ACA 5'
E) 3'
AAA-GAA-TAA-CAA 5'
3' AAA-GAA-TAA-CAA 5'
21
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6) What amino acid sequence will be generated, based on the
following mRNA codon sequence?
5' AUG-UCU-UCG-UUA-UCC-UUG
3'
A) met-arg-glu-arg-glu-arg
B)
met-glu-arg-arg-glu-leu
C) met-ser-leu-ser-leu-ser
D)
met-ser-ser-leu-ser-leu
E) met-leu-phe-arg-glu-glu
met-ser-ser-leu-ser-leu
A peptide has the sequence NH2-phe-pro-lys-gly-phe-pro-COOH. Which of
the following
sequences in the coding strand of the DNA could
code for this peptide?
A) 3' UUU-CCC-AAA-GGG-UUU-CCC
B) 3'
AUG-AAA-GGG-TTT-CCC-AAA-GGG
C) 5' TTT-CCC-AAA-GGG-TTT-CCC
D)
5' GGG-AAA-TTT-AAA-CCC-ACT-GGG
E) 5' ACT-TAC-CAT-AAA-CAT-TAC-UGA
5' TTT-CCC-AAA-GGG-TTT-CCC
Given the locally unwound double strand in Figure 14.3, in which
direction does the RNA
polymerase move?
A) 3' → 5' along the
template strand
B) 5' → 3' along the template strand
C) 3' →
5' along the complementary strand
D) 5' → 3'; along the
complementary strand
E) 5' → 3' along the double-stranded DNA
3' → 5' along the template strand
In the transcription event of the previous DNA, where would the
promoter be located?
A) at the 3' end of the newly made
RNA
B) to the right of the template strand
C) to the left of
the template strand
D) to the right of the sense strand
E)
to the left of the sense strand
to the right of the template strand
The dipeptide that will form will be
A)
cysteine-alanine.
B) proline-threonine.
C)
glycine-cysteine.
D) alanine-alanine.
E) threonine-glycine.
proline-threonine.
The anticodon loop of the first tRNA that will complement this mRNA
is
A) 3' GGC 5'
B) 5' GGC 3'
C) 5' ACG 3'.
D) 5'
UGC 3'.
E) 3' UGC 5'.
3' GGC 5'
What type of bonding is responsible for maintaining the shape of the
tRNA molecule in
Figure 14.5?
A) covalent bonding between
sulfur atoms
B) ionic bonding between phosphates
C) hydrogen
bonding between base pairs
D) van der Waals interactions between
hydrogen atoms
E) peptide bonding between amino acids
hydrogen bonding between base pairs
Figure 14.5 represents tRNA that recognizes and binds a particular
amino acid (in this
instance, phenylalanine). Which codon on the
mRNA strand codes for this amino acid?
A) UGG
B) GUG
C)
GUA
D) UUC
E) CAU
UUC
The tRNA shown in Figure 14.5 has its 3' end projecting beyond its 5
end. What will occur
at this 3' end?
A) The codon and
anticodon complement one another.
B) The amino acid binds
covalently.
C) The excess nucleotides (ACCA) will be cleaved off
at the ribosome.
D) The small and large subunits of the ribosome
will attach to it.
E) The 5' cap of the mRNA will become
covalently bound.
The amino acid binds covalently.
The enzyme polynucleotide phosphorylase randomly assembles
nucleotides into a
polynucleotide polymer.
You add
polynucleotide phosphorylase to a solution of adenosine triphosphate
and guanosine
triphosphate. How many artificial mRNA 3 nucleotide
codons would be possible?
A) 3
B) 4
C) 8
D)
16
E) 64
8
You add polynucleotide phosphorylase to a solution of ATP, GTP, and
UTP. How many
artificial mRNA 3 nucleotide codons would be
possible?
A) 3
B) 6
C) 9
D) 27
E) 81
27
A transfer RNA (#1) attached to the amino acid lysine enters the
ribosome. The lysine binds to
the growing polypeptide on the
other tRNA (#2) already in the ribosome.
3) Where does tRNA #2
move to after this bonding of lysine to the polypeptide?
A) A
site
B) P site
C) E site
D) exit tunnel
E)
directly to the cytosol
E site
Which component of the complex described enters the exit tunnel
through the large subunit of
the ribosome?
A) tRNA with
attached lysine (#1)
B) tRNA with polypeptide (#2)
C) tRNA
that no longer has attached amino acid
D) newly formed
polypeptide
E) initiation and elongation factors
newly formed polypeptide
In eukaryotic cells, transcription cannot begin until
A) the two
DNA strands have completely separated and exposed the
promoter.
B) several transcription factors have bound to the
promoter.
C) the 5' caps are removed from the
mRNA.
D) the DNA introns are removed from the template.
E)
DNA nucleases have isolated the transcription unit.
several transcription factors have bound to the promoter.
Which of the following is not true of a codon?
A) It consists of
three nucleotides.
B) It may code for the same amino acid as
another codon.
C) It never codes for more than one amino
acid.
D) It extends from one end of a tRNA molecule.
E) It
is the basic unit of the genetic code.
It extends from one end of a tRNA molecule.
The anticodon of a particular tRNA molecule is
A) complementary
to the corresponding mRNA codon.
B) complementary to the
corresponding triplet in rRNA.
C) the part of tRNA that bonds to
a specific amino acid.
D) changeable, depending on the amino acid
that attaches to the tRNA.
E) catalytic, making the tRNA a ribozyme.
complementary to the corresponding mRNA codon.
Which of the following is not true of RNA processing?
A) Exons
are cut out before mRNA leaves the nucleus.
B) Nucleotides may be
added at both ends of the RNA.
C) Ribozymes may function in RNA
splicing.
D) RNA splicing can be catalyzed by
spliceosomes.
E) A primary transcript is often much longer than
the final RNA molecule that leaves the
nucleus.
Exons are cut out before mRNA leaves the nucleus.
Which component is not directly involved in translation?
A)
mRNA
B) DNA
C) tRNA
D) ribosomes
E) GTP
DNA
Using the following figure, identify a 5' → 3' sequence of
nucleotides in the DNA template
strand for an mRNA coding for the
polypeptide sequence Phe-Pro-Lys.
A) 5´-UUUGGGAAA-3'
B) 5´-GAACCCCTT-3'
C)
5´-AAAACCTTT-3'
D) 5´-CTTCGGGAA-3'
E) 5´-AAACCCUUU-3'
5´-CTTCGGGAA-3'
Which of the following mutations would be most likely to have a
harmful effect on an
organism?
A) a nucleotide-pair
substitution
B) a deletion of three nucleotides near the middle
of a gene
C) a single nucleotide deletion in the middle of an
intron
D) a single nucleotide deletion near the end of the coding
sequence
E) a single nucleotide insertion downstream of, and
close to, the start of the coding sequence
a single nucleotide insertion downstream of, and close to, the start of the coding sequence