1) What do we mean when we use the terms monohybrid cross and
dihybrid cross?
A) A monohybrid cross involves a single parent,
whereas a dihybrid cross involves two parents.
B) A monohybrid
cross produces a single progeny, whereas a dihybrid cross produces
two
progeny.
C) A dihybrid cross involves organisms that are
heterozygous for two characters, and a
monohybrid cross involves
only one.
D) A monohybrid cross is performed for one generation,
whereas a dihybrid cross is performed
for two
generations.
E) A monohybrid cross results in a 9:3:3:1 ratio,
whereas a dihybrid cross gives a 3:1 ratio.
A dihybrid cross involves organisms that are heterozygous for two
characters, and a
monohybrid cross involves only one.
What was the most significant conclusion that Gregor Mendel drew from
his experiments with
pea plants?
A) There is considerable
genetic variation in garden peas.
B) Traits are inherited in
discrete units, and are not the results of
"blending."
C) Recessive genes occur more
frequently in the F1 generation than do dominant ones.
D) Genes
are composed of DNA.
E) An organism that is homozygous for many
recessive traits is at a disadvantage.
Traits are inherited in discrete units, and are not the results of "blending."
How many unique gametes could be produced through independent
assortment by an
individual with the genotype AaBbCCDdEE?
A)
4
B) 8
C) 16
D) 32
E) 64
8
The individual with genotype AaBbCCDdEE can make many kinds of
gametes. Which of the
following is the major reason?
A)
segregation of maternal and paternal alleles
B) recurrent
mutations forming new alleles
C) crossing over during prophase
I
D) different possible assortment of chromosomes into
gametes
E) the tendency for dominant alleles to segregate together
different possible assortment of chromosomes into gametes
Why did Mendel continue some of his experiments to the F2 or F3
generation?
A) to obtain a larger number of offspring on which to
base statistics
B) to observe whether or not a recessive trait
would reappear
C) to observe whether or not the dominant trait
would reappear
D) to distinguish which alleles were
segregating
E) to be able to describe the frequency of recombination
to observe whether or not a recessive trait would reappear
When crossing an organism that is homozygous recessive for a single
trait with a
heterozygote, what is the chance of producing an
offspring with the homozygous recessive
phenotype?
A)
0%
B) 25%
C) 50%
D) 75%
E) 100%
50%
Which of the following differentiates between independent assortment
and segregation?
A) The law of independent assortment requires
describing two or more genes relative to one
another.
B) The
law of segregation requires describing two or more genes relative to
one another.
C) The law of segregation requires having two or
more generations to describe.
D) The law of independent
assortment is accounted for by observations of prophase I.
E) The
law of segregation is accounted for by anaphase of mitosis.
The law of independent assortment requires describing two or more
genes relative to one
another.
Two plants are crossed, resulting in offspring with a 3:1 ratio for a
particular trait. What does
this suggest?
A) that the
parents were true-breeding for contrasting traits
B) that the
trait shows incomplete dominance
C) that a blending of traits has
occurred
D) that the parents were both heterozygous for a single
trait
E) that each offspring has the same alleles for each of two traits
that the parents were both heterozygous for a single trait
A sexually reproducing animal has two unlinked genes, one for head
shape (H) and one for
tail length (T). Its genotype is HhTt.
Which of the following genotypes is possible in a gamete
from
this organism?
A) tt
B) Hh
C) HhTt
D) T
E) HT
HT
Mendel accounted for the observation that traits that had disappeared
in the F1 generation
reappeared in the F2 generation by proposing
that
A) new mutations were frequently generated in the F2
progeny, "reinventing" traits that had
been
lost in the F1.
B) the mechanism controlling the
appearance of traits was different between the F1 and the
F2
plants.
C) traits can be dominant or recessive, and the
recessive traits were obscured by the dominant
ones in the
F1.
D) the traits were lost in the F1 due to dominance of the
parental traits.
E) members of the F1 generation had only one
allele for each trait, but members of the F2 had
two alleles for
each trait.
traits can be dominant or recessive, and the recessive traits were
obscured by the dominant
ones in the F1.
The fact that all seven of the pea plant traits studied by Mendel
obeyed the principle of
independent assortment most probably
indicates which of the following?
A) None of the traits obeyed
the law of segregation.
B) The diploid number of chromosomes in
the pea plants was 7.
C) All of the genes controlling the traits
were located on the same chromosome.
D) All of the genes
controlling the traits behaved as if they were on different
chromosomes.
E) The formation of gametes in plants occurs by
mitosis only.
All of the genes controlling the traits behaved as if they were on different chromosomes.
Mendel's observation of the segregation of alleles in gamete
formation has its basis in which
of the following phases of cell
division?
A) prophase I of meiosis
B) anaphase II of
meiosis
C) metaphase I of meiosis
D) anaphase I of
meiosis
E) anaphase of mitosisanaphase I of meiosis
anaphase I of meiosis
Mendel's second law of independent assortment has its basis
in which of the following events
of meiosis I?
A) synapsis
of homologous chromosomes
B) crossing over
C) alignment of
tetrads at the equator
D) separation of homologs at
anaphase
E) separation of cells at telophase
alignment of tetrads at the equator
Why did the F1 offspring of Mendel's classic pea cross always
look like one of the two
parental varieties?
A) No genes
interacted to produce the parental phenotype.
B) Each allele
affected phenotypic expression.
C) The traits blended together
during fertilization.
D) One allele was dominant.
E)
Phenotype was not dependent on genotype.
One allele was dominant.
Black fur in mice (B) is dominant to brown fur (b). Short tails (T)
are dominant to long tails
(t). What fraction of the progeny of
crosses BbTt × BBtt will be expected to have black fur and
long
tails?
A) 1/16
B) 3/16
C) 3/8
D) 1/2
E) 9/16
1/2
In certain plants, tall is dominant to short. If a heterozygous plant
is crossed with a
homozygous tall plant, what is the probability
that the offspring will be short?
A) 1
B) 1/2
C)
1/4
D) 1/6
E) 0
0
17) In the cross AaBbCc × AaBbCc, what is the probability of
producing the genotype AABBCC?
A) 1/4
B) 1/8
C)
1/16
D) 1/32
E) 1/64
1/64
18) Given the parents AABBCc × AabbCc, assume simple dominance for
each trait and
independent assortment. What proportion of the
progeny will be expected to phenotypically
resemble the first
parent?
A) 1/4
B) 1/8
C) 3/4
D) 3/8
E) 1
3/8
19) Which of the following is the best statement of the use of the
addition rule of probability?
A) the probability that two or more
independent events will both occur
B) the probability that two or
more independent events will both occur in the offspring of one
set
of parents
C) the probability that either one of two
independent events will occur
D) the probability of producing two
or more heterozygous offspring
E) the likelihood that a trait is
due to two or more meiotic events
the probability that either one of two independent events will occur
20) Which of the following calculations require that you utilize the
addition rule?
A) Calculate the probability of black offspring
from the cross AaBb × AaBb, when B is the
symbol for
black.
B) Calculate the probability of children with both cystic
fibrosis and polydactyly when parents
are each heterozygous for
both genes.
C) Calculate the probability of each of four children
having cystic fibrosis if the parents are
both
heterozygous.
D) Calculate the probability of a child
having either sickle-cell anemia or cystic fibrosis if
parents
are each heterozygous for both.
E) Calculate the probability of
purple flower color in a plot of 50 plants seeded from a
self-
fertilizing heterozygous parent plant.
Calculate the probability of a child having either sickle-cell anemia
or cystic fibrosis if
parents are each heterozygous for both.
Marfan syndrome in humans is caused by an abnormality of the
connective tissue protein
fibrillin. Patients are usually very
tall and thin, with long spindly fingers, curvature of the
spine,
sometimes weakened arterial walls, and sometimes ocular
problems, such as lens dislocation.
Which of the following would
you conclude about Marfan syndrome from this information?
A) It
is recessive.
B) It is dominant.
C) It has a late age of
onset (> 60).
D) It is pleiotropic.
E) It is epistatic.
It is pleiotropic.
In cattle, roan coat color (mixed red and white hairs) occurs in the
heterozygous (Rr)
offspring of red (RR) and white (rr)
homozygotes. Which of the following crosses would
produce
offspring in the ratio of 1 red:2 roan:1 white?
A) red ×
white
B) roan × roan
C) white × roan
D) red ×
roan
E) The answer cannot be determined from the information provided.
roan × roan
Which of the following describes the ability of a single gene to have
multiple phenotypic
effects?
A) incomplete dominance
B)
multiple alleles
C) pleiotropy
D) epistasis
Answer: C
pleiotropy
Cystic fibrosis affects the lungs, the pancreas, the digestive
system, and other organs,
resulting in symptoms ranging from
breathing difficulties to recurrent infections. Which of
the
following terms best describes this?
A) incomplete
dominance
B) multiple alleles
C) pleiotropy
D)
epistasis
E) codominance
pleiotropy
Which of the following is an example of polygenic
inheritance?
A) pink flowers in snapdragons
B) the ABO blood
group in humans
C) Huntington's disease in humans
D)
white and purple flower color in peas
E) skin pigmentation in humans
skin pigmentation in humans
Hydrangea plants of the same genotype are planted in a large flower
garden. Some of the
plants produce blue flowers and others pink
flowers. This can be best explained by which of
the
following?
A) the knowledge that multiple alleles are
involved
B) the allele for blue hydrangea being completely
dominant
C) the alleles being codominant
D) the fact that a
mutation has occurred
E) environmental factors such as soil pH
environmental factors such as soil pH
Which of the following provides an example of epistasis?
A)
Recessive genotypes for each of two genes (aabb) result in an albino
corn snake.
B) The allele b17 produces a dominant phenotype,
although b1 through b16 do not.
C) In rabbits and many other
mammals, one genotype (ee) prevents any fur color
from
developing.
D) In Drosophila (fruit flies), white eyes
can be due to an X-linked gene or to a combination of
other
genes.
E) In cacti, there are several genes for the type of spines.
In rabbits and many other mammals, one genotype (ee) prevents any fur
color from
developing.
A scientist discovers a DNA-based test for one allele of a particular
gene. This and only this
allele, if homozygous, produces an
effect that results in death at or about the time of birth. Of
the
following, which is the best use of this discovery?
A)
Screen all newborns of an at-risk population.
B) Design a test
for identifying heterozygous carriers of the allele.
C) Introduce
a normal allele into deficient newborns.
D) Follow the
segregation of the allele during meiosis.
E) Test school-age
children for the disorder.
Design a test for identifying heterozygous carriers of the allele.
The frequency of heterozygosity for the sickle-cell anemia allele is
unusually high,
presumably because this reduces the frequency of
malaria. Such a relationship is related to which
of the
following?
A) Mendel's law of independent
assortment
B) Mendel's law of segregation
C)
Darwin's explanation of natural selection
D)
Darwin's observations of competition
E) the malarial
parasite changing the allele
Darwin's explanation of natural selection
One of two major forms of a human condition called neurofibromatosis
(NF 1) is inherited as
a dominant gene, although it may range
from mildly to very severely expressed. If a young child
is the
first in her family to be diagnosed, which of the following is the
best explanation?
A) The mother carries the gene but does not
express it at all.
B) One of the parents has very mild expression
of the gene.
C) The condition skipped a generation in the
family.
D) The child has a different allele of the gene than the parents.
One of the parents has very mild expression of the gene.