Pharmacology Cough, Congestion, URI allergic response Flashcards


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created 1 year ago by meltyxoxo
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1

Oral antihistamines and what they relieve

  1. First gen - diphenhydramine (Benadryl) zzZZZ
  2. Second gen - cetirizine (Zyrtec)
  3. Third gen - fexofenadine (Allegra)

These relieve sneezing, rhinorrhea, and nasal itching

2

drugs for sympathomimetics (decongestants)

  • pseudoephedrine (oral)
  • pehnylephrine (oral, drops, spray)
  • oxymetazoline (spray)

3

how does sympathomimetics (decongestants) work?

  • Reduce nasal congestion by activating alpha1-adrenergic receptors on nasal blood vessels = vasoconstriction = decreased swelling & drainage

4

side effects of sympathomimetics (decongestants)

  • rebound congestion (use topical agent for 3-5 days)
  • CNS stimulator
  • dangerous for pts w CV events
  • ABUSE - kept locked behind the counter

5

Opioid antitussives (anti cough)

codeine, hydrocodone

6

Nonopioid antitussives (anti cough)

dextromethorphan, benzonatate zzzZZZZZ

7

Drugs for congestion include

  1. Exporants
  2. Mucolytics

8

prototype drug for exporants

guaifenesine

9

what does guaifenesine do?

makes ur cough more productive by stimulating flow of repiratory tract secretions

10

prototype drug for mucolytics

acetylcysteine

11

what does acetylcysteine do?

makes mucus more watery for a more productive cough

12

other drugs that can treat respiratory conditions include

Abx, antiviral drugs, antifungals, diuretics, and O2