Dextrose (D50, D25, D10)
Duration of Action
- Onset:<1min
- Peak Effect: Variable
- Duration: Variable
Diazepam (Valium)
Duration of Action
- Onset: 1 - 5mins
- Peak Effect: within mins
- Duration: 20 - 50mins
Diphenhydramine hydrochloride (Benadryl)
Duration of Action
- Onset: 15 - 30mins
- Peak Effect: 1hr
- Duration: 3 - 12hrs
Epinephrine (1:1000, 1:10,000)
Duration of Action
- Onset: Immediate
- Peak Effect: Minutes
- Duration: Several minutes
Fentanyl citrate (Sublimaze)
Duration of Action
- Onset: The onset of action is almost immediate when the drug is given intravenously; however, the maximal analgesic and respiratory depressant effect may not be noted for several minutes.
- Peak Effect: The peak respiratory depressant effect of a single intravenous dose of is noted as 5 to 15 minutes following injection.
- Duration: The usual duration of action of the analgesic effect is 30 to 60 minutes after a single intravenous dose of up to 100 mcg.
Glucagon
Duration of Action
- Onset: 1min
- Peak Effect: 30mins
- Duration: Variable (generally 9 - 17mins)
Hydrocortisone sodium succinate (Cortef, Solu-Cortef)
Duration of Action
- Onset: Mins - hrs (depending on indication).
- Peak Effect: 8 - 12hrs
Hydroxocobalamin (Vitamin B 12)
*cyano-kit
Unknown
Ketamine (Ketalar)
Duration of Action
- Onset: 10mins
- Peak Effect: 1 - 2hrs
- Duration: 2 - 6hrs
Lorazepam (Ativan)
Duration of Action
- Onset: 1 - 5mins
- Peak Effect: Variable
- Duration: 6 - 8hrs
Methylprednisolone sodium succinate (Solu-Medrol)
Duration of Action
- Onset: Mins - hrs (depending on indication).
- Peak Effect: 8 - 12hrs
Midazolam (Versed)
Duration of Action
- Onset: 1 - 3mins (IV) & dose dependent
- Peak Effect: Variable
- Duration: 2 - 6hrs & dose dependent
Naloxone (Narcan)
Duration of Action
- Onset: within 2mins
- Peak Effect: Variable
- Duration: 30 - 60 minutes
Ondansetron (Zofran)
Duration of Action
- Onset: Approximately 30 minutes
-
Half-life:
Children <5 years: 2-3 hours
Adults : 3-6 hours
Pralidoxime chloride (2-PAM, Protopam)
Duration of Action
- Onset: Minutes
- Peak Effect: Variable
- Duration: Variable
Tranexamic acid (TXA)
Duration of Action
- Onset: Unknown
- Peak Effect: Unknown
- Duration: 7-8 hours