Asthma is a heterogenous disease, usually characterized by chronic airway_______.
Inflammation
Asthma pathophysiology include the smooth muscle surrounding the ______ is stimulated by histamines and leukotrienes causing bronchoconstriction.
Bronchioles
The immune system’s response to asthma, include bronchial hyperreactivity, eosinophil and neutrophil infiltration happen during the _________phase.
Late phase
What are some known risk factors for the development of asthma?
- Atopy
- Secondhand smoke (preschool age)
- Dust mites & cockroaches
- RSV in infants
- Obesity
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What are some known allergens and triggers that can cause an asthma attack?
- Dust mites & cockroaches
- Pets/pet dander
- Molds
- Pollen
- Exercise
- Community Acquired Pneumonia
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What are the 4 MAIN consequences of uncontrolled asthma?
- Airway Inflammation (AI)
- Bronchoconstriction
- Airway Hyperresponsiveness (AHR)
- Airway Remodeling
What the hallmark signs/symptoms of asthma?
- SOB
- Wheezing during expiration
- Cough at night
What test is the gold standard for diagnosing asthma?
Spirometry